登録情報 | データベース: PDB / ID: 7np1 |
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タイトル | Crystal Structure of the SARS-CoV-2 Receptor Binding Domain in Complex with Antibody ION-360 |
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要素 | - Immunoblobulin light chain
- Immunoglobulin gamma-1 heavy chain
- Spike protein S1
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キーワード | VIRAL PROTEIN / Antibody Immune System |
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機能・相同性 | 機能・相同性情報
Maturation of spike protein / viral translation / Translation of Structural Proteins / Virion Assembly and Release / host cell surface / host extracellular space / suppression by virus of host tetherin activity / Induction of Cell-Cell Fusion / structural constituent of virion / entry receptor-mediated virion attachment to host cell ...Maturation of spike protein / viral translation / Translation of Structural Proteins / Virion Assembly and Release / host cell surface / host extracellular space / suppression by virus of host tetherin activity / Induction of Cell-Cell Fusion / structural constituent of virion / entry receptor-mediated virion attachment to host cell / host cell endoplasmic reticulum-Golgi intermediate compartment membrane / receptor-mediated endocytosis of virus by host cell / Attachment and Entry / membrane fusion / positive regulation of viral entry into host cell / receptor-mediated virion attachment to host cell / receptor ligand activity / symbiont-mediated suppression of host innate immune response / host cell surface receptor binding / fusion of virus membrane with host plasma membrane / fusion of virus membrane with host endosome membrane / viral envelope / virion attachment to host cell / SARS-CoV-2 activates/modulates innate and adaptive immune responses / host cell plasma membrane / virion membrane / identical protein binding / membrane / plasma membrane類似検索 - 分子機能 Spike (S) protein S1 subunit, receptor-binding domain, SARS-CoV-2 / Spike (S) protein S1 subunit, N-terminal domain, SARS-CoV-like / Betacoronavirus spike (S) glycoprotein S1 subunit N-terminal (NTD) domain profile. / Spike glycoprotein, N-terminal domain superfamily / Betacoronavirus spike (S) glycoprotein S1 subunit C-terminal (CTD) domain profile. / Spike glycoprotein, betacoronavirus / Spike (S) protein S1 subunit, receptor-binding domain, betacoronavirus / Spike S1 subunit, receptor binding domain superfamily, betacoronavirus / Betacoronavirus spike glycoprotein S1, receptor binding / Spike glycoprotein S1, N-terminal domain, betacoronavirus-like ...Spike (S) protein S1 subunit, receptor-binding domain, SARS-CoV-2 / Spike (S) protein S1 subunit, N-terminal domain, SARS-CoV-like / Betacoronavirus spike (S) glycoprotein S1 subunit N-terminal (NTD) domain profile. / Spike glycoprotein, N-terminal domain superfamily / Betacoronavirus spike (S) glycoprotein S1 subunit C-terminal (CTD) domain profile. / Spike glycoprotein, betacoronavirus / Spike (S) protein S1 subunit, receptor-binding domain, betacoronavirus / Spike S1 subunit, receptor binding domain superfamily, betacoronavirus / Betacoronavirus spike glycoprotein S1, receptor binding / Spike glycoprotein S1, N-terminal domain, betacoronavirus-like / Betacoronavirus-like spike glycoprotein S1, N-terminal / Spike glycoprotein S2, coronavirus, heptad repeat 1 / Spike glycoprotein S2, coronavirus, heptad repeat 2 / Coronavirus spike (S) glycoprotein S2 subunit heptad repeat 2 (HR2) region profile. / Coronavirus spike (S) glycoprotein S2 subunit heptad repeat 1 (HR1) region profile. / Spike glycoprotein S2 superfamily, coronavirus / Spike glycoprotein S2, coronavirus / Coronavirus spike glycoprotein S2 / Coronavirus spike glycoprotein S1, C-terminal / Coronavirus spike glycoprotein S1, C-terminal類似検索 - ドメイン・相同性 |
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生物種 | ![](img/tx_virus.gif) Severe acute respiratory syndrome coronavirus 2 (ウイルス)
Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.8 Å |
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データ登録者 | Hall, G. / Cowan, R. / Carr, M. |
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引用 | ジャーナル: Front Immunol / 年: 2021 タイトル: Cross-Reactive SARS-CoV-2 Neutralizing Antibodies From Deep Mining of Early Patient Responses. 著者: Bullen, G. / Galson, J.D. / Hall, G. / Villar, P. / Moreels, L. / Ledsgaard, L. / Mattiuzzo, G. / Bentley, E.M. / Masters, E.W. / Tang, D. / Millett, S. / Tongue, D. / Brown, R. / ...著者: Bullen, G. / Galson, J.D. / Hall, G. / Villar, P. / Moreels, L. / Ledsgaard, L. / Mattiuzzo, G. / Bentley, E.M. / Masters, E.W. / Tang, D. / Millett, S. / Tongue, D. / Brown, R. / Diamantopoulos, I. / Parthiban, K. / Tebbutt, C. / Leah, R. / Chaitanya, K. / Ergueta-Carballo, S. / Pazeraitis, D. / Surade, S.B. / Ashiru, O. / Crippa, L. / Cowan, R. / Bowler, M.W. / Campbell, J.I. / Lee, W.J. / Carr, M.D. / Matthews, D. / Pfeffer, P. / Hufton, S.E. / Sawmynaden, K. / Osbourn, J. / McCafferty, J. / Karatt-Vellatt, A. |
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履歴 | 登録 | 2021年2月26日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2021年11月17日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2024年1月31日 | Group: Data collection / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model |
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