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Yorodumi- PDB-7mgq: AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for d... -
+Open data
-Basic information
Entry | Database: PDB / ID: 7mgq | ||||||
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Title | AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans | ||||||
Components | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase | ||||||
Keywords | STRUCTURAL PROTEIN / Isomerase / ligand / complex | ||||||
Function / homology | Function and homology information phosphoribosylaminoimidazolecarboxamide formyltransferase activity / IMP cyclohydrolase activity / 'de novo' IMP biosynthetic process Similarity search - Function | ||||||
Biological species | Cryptococcus neoformans (fungus) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.67 Å | ||||||
Authors | Wizrah, M.S. / Chua, S.M.H. / Luo, Z. / Manik, M.K. / Pan, M. / Whyte, J.M. / Robertson, A.B. / Kappler, U. / Kobe, B. / Fraser, J.A. | ||||||
Funding support | Australia, 1items
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Citation | Journal: J.Biol.Chem. / Year: 2022 Title: AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans. Authors: Wizrah, M.S.I. / Chua, S.M.H. / Luo, Z. / Manik, M.K. / Pan, M. / Whyte, J.M.L. / Robertson, A.A.B. / Kappler, U. / Kobe, B. / Fraser, J.A. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 7mgq.cif.gz | 1.1 MB | Display | PDBx/mmCIF format |
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PDB format | pdb7mgq.ent.gz | 767.8 KB | Display | PDB format |
PDBx/mmJSON format | 7mgq.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/mg/7mgq ftp://data.pdbj.org/pub/pdb/validation_reports/mg/7mgq | HTTPS FTP |
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-Related structure data
Related structure data | 1pkxS S: Starting model for refinement |
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Similar structure data | Similarity search - Function & homologyF&H Search |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: 1
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