- PDB-7lru: Crystal structure of SFPQ-NONO-SFPQ chimeric protein homodimer -
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Basic information
Entry
Database: PDB / ID: 7lru
Title
Crystal structure of SFPQ-NONO-SFPQ chimeric protein homodimer
Components
Splicing factor, proline- and glutamine-rich,Isoform 2 of Non-POU domain-containing octamer-binding protein,Isoform Short of Splicing factor, proline- and glutamine-rich
Keywords
RNA BINDING PROTEIN / DBHS Protein / Nuclear Protein / Nucleic Acid Binding / Paraspeckle Formation
Function / homology
Function and homology information
PTK6 Regulates Proteins Involved in RNA Processing / negative regulation of circadian rhythm / alternative mRNA splicing, via spliceosome / paraspeckles / Suppression of apoptosis / positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway / negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway / activation of innate immune response / RNA splicing / double-strand break repair via homologous recombination ...PTK6 Regulates Proteins Involved in RNA Processing / negative regulation of circadian rhythm / alternative mRNA splicing, via spliceosome / paraspeckles / Suppression of apoptosis / positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway / negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway / activation of innate immune response / RNA splicing / double-strand break repair via homologous recombination / regulation of circadian rhythm / mRNA processing / fibrillar center / nuclear matrix / histone deacetylase binding / circadian rhythm / RNA polymerase II transcription regulator complex / rhythmic process / chromosome / DNA recombination / transcription cis-regulatory region binding / nuclear speck / chromatin remodeling / DNA repair / innate immune response / negative regulation of DNA-templated transcription / chromatin binding / regulation of DNA-templated transcription / chromatin / negative regulation of transcription by RNA polymerase II / protein homodimerization activity / positive regulation of transcription by RNA polymerase II / DNA binding / RNA binding / nucleoplasm / identical protein binding / membrane / nucleus / cytosol Similarity search - Function
B: Splicing factor, proline- and glutamine-rich,Isoform 2 of Non-POU domain-containing octamer-binding protein,Isoform Short of Splicing factor, proline- and glutamine-rich
B: Splicing factor, proline- and glutamine-rich,Isoform 2 of Non-POU domain-containing octamer-binding protein,Isoform Short of Splicing factor, proline- and glutamine-rich
B: Splicing factor, proline- and glutamine-rich,Isoform 2 of Non-POU domain-containing octamer-binding protein,Isoform Short of Splicing factor, proline- and glutamine-rich
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