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Yorodumi- PDB-7lop: Crystal structure of SARS-CoV-2 receptor binding domain in comple... -
+Open data
-Basic information
Entry | Database: PDB / ID: 7lop | ||||||||||||||||||
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Title | Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CV05-163 and CR3022 | ||||||||||||||||||
Components |
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Keywords | VIRAL PROTEIN/IMMUNE SYSTEM / SARS-CoV-2 / receptor binding domain / coronavirus / COVID-19 / antibody / Fab / IMMUNE SYSTEM / VIRAL PROTEIN-IMMUNE SYSTEM complex | ||||||||||||||||||
Function / homology | Function and homology information Maturation of spike protein / viral translation / Translation of Structural Proteins / Virion Assembly and Release / host cell surface / host extracellular space / suppression by virus of host tetherin activity / Induction of Cell-Cell Fusion / structural constituent of virion / entry receptor-mediated virion attachment to host cell ...Maturation of spike protein / viral translation / Translation of Structural Proteins / Virion Assembly and Release / host cell surface / host extracellular space / suppression by virus of host tetherin activity / Induction of Cell-Cell Fusion / structural constituent of virion / entry receptor-mediated virion attachment to host cell / host cell endoplasmic reticulum-Golgi intermediate compartment membrane / receptor-mediated endocytosis of virus by host cell / Attachment and Entry / membrane fusion / positive regulation of viral entry into host cell / receptor-mediated virion attachment to host cell / receptor ligand activity / symbiont-mediated suppression of host innate immune response / host cell surface receptor binding / fusion of virus membrane with host plasma membrane / fusion of virus membrane with host endosome membrane / viral envelope / virion attachment to host cell / SARS-CoV-2 activates/modulates innate and adaptive immune responses / host cell plasma membrane / virion membrane / identical protein binding / membrane / plasma membrane Similarity search - Function | ||||||||||||||||||
Biological species | Homo sapiens (human) Severe acute respiratory syndrome coronavirus 2 | ||||||||||||||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.246 Å | ||||||||||||||||||
Authors | Yuan, M. / Zhu, X. / Wilson, I.A. | ||||||||||||||||||
Funding support | United States, 5items
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Citation | Journal: Science / Year: 2021 Title: Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants. Authors: Yuan, M. / Huang, D. / Lee, C.D. / Wu, N.C. / Jackson, A.M. / Zhu, X. / Liu, H. / Peng, L. / van Gils, M.J. / Sanders, R.W. / Burton, D.R. / Reincke, S.M. / Pruss, H. / Kreye, J. / Nemazee, ...Authors: Yuan, M. / Huang, D. / Lee, C.D. / Wu, N.C. / Jackson, A.M. / Zhu, X. / Liu, H. / Peng, L. / van Gils, M.J. / Sanders, R.W. / Burton, D.R. / Reincke, S.M. / Pruss, H. / Kreye, J. / Nemazee, D. / Ward, A.B. / Wilson, I.A. | ||||||||||||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 7lop.cif.gz | 858 KB | Display | PDBx/mmCIF format |
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PDB format | pdb7lop.ent.gz | 709.7 KB | Display | PDB format |
PDBx/mmJSON format | 7lop.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 7lop_validation.pdf.gz | 531.8 KB | Display | wwPDB validaton report |
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Full document | 7lop_full_validation.pdf.gz | 555.4 KB | Display | |
Data in XML | 7lop_validation.xml.gz | 86.2 KB | Display | |
Data in CIF | 7lop_validation.cif.gz | 124.2 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/lo/7lop ftp://data.pdbj.org/pub/pdb/validation_reports/lo/7lop | HTTPS FTP |
-Related structure data
Related structure data | 6w41S S: Starting model for refinement |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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