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- PDB-7ew5: immune complex of HPV6 L1 pentamer and neutralizing antibody 13H5 -

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Open data

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Basic information

Entry

Database: PDB / ID: 7ew5

Title

immune complex of HPV6 L1 pentamer and neutralizing antibody 13H5

Components

Heavy chain of 13H5
Light chain of 13H5
Major capsid protein L1

Keywords

VIRAL PROTEIN / immune complex

Function / homology

Function and homology information

T=7 icosahedral viral capsid / endocytosis involved in viral entry into host cell / virion attachment to host cell / host cell nucleus / structural molecule activity
Similarity search - Function

Biological species

Human papillomavirus type 6

Mus musculus (house mouse)

Method

X-RAY DIFFRACTION /

SYNCHROTRON /

MOLECULAR REPLACEMENT / Resolution: 3.606 Å

Authors

Wang, Z.P. / Wang, D.N. / Gu, Y. / Li, S.W.

Funding support

China, 1items

Citation

Journal: Sci Bull (Beijing) / Year: 2024
Title: Rational design of a cross-type HPV vaccine through immunodominance shift guided by a cross-neutralizing antibody.
Authors: Wang, Z. / Wang, D. / Chen, J. / Gao, F. / Jiang, Y. / Yang, C. / Qian, C. / Chi, X. / Zhang, S. / Xu, Y. / Lu, Y. / Shen, J. / Zhang, C. / Li, J. / Zhou, L. / Li, T. / Zheng, Q. / Yu, H. / ...

History

Deposition	May 24, 2021	Deposition site: PDBJ / Processing site: PDBJ
Revision 1.0	Jun 1, 2022	Provider: repository / Type: Initial release
Revision 1.1	Jun 8, 2022	Group: Derived calculations / Category: pdbx_struct_assembly / pdbx_struct_assembly_gen
Revision 1.2	Nov 29, 2023	Group: Data collection / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model / struct_ncs_dom_lim Item: _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id ..._struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id
Revision 1.3	Oct 23, 2024	Group: Structure summary / Category: pdbx_entry_details / pdbx_modification_feature
Revision 1.4	Feb 26, 2025	Group: Database references / Category: citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year

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Structure visualization

Structure viewer	Molecule: MolmilJmol/JSmol

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Downloads & links

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Download

PDBx/mmCIF format	7ew5.cif.gz	3.2 MB	Display	PDBx/mmCIF format
PDB format	pdb7ew5.ent.gz		Display	PDB format
PDBx/mmJSON format	7ew5.json.gz		Tree view	PDBx/mmJSON format
Others	Other downloads

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Validation report

Summary document	7ew5_validation.pdf.gz	689.1 KB	Display	wwPDB validaton report
Full document	7ew5_full_validation.pdf.gz	819.1 KB	Display
Data in XML	7ew5_validation.xml.gz	278.5 KB	Display
Data in CIF	7ew5_validation.cif.gz	370.2 KB	Display
Arichive directory	https://data.pdbj.org/pub/pdb/validation_reports/ew/7ew5 ftp://data.pdbj.org/pub/pdb/validation_reports/ew/7ew5	HTTPS FTP

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Related structure data

Related structure data	7f8iC 1plgS 5y9eS S: Starting model for refinement C: citing same article (ref.)
Similar structure data	Similarity search - Function & homologyF&H Search Similarity search - FunctionF&H Search Similarity search - HomologyF&H Search

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Links

PDB pages	PDBj / wwPDB / NCBI
Related items in Molecule of the Month	#221 - May 2018 Human Papillomavirus and Vaccines similarity (4) #21 - Sep 2001 Antibodies similarity (1) #256 - Apr 2021 SARS-CoV-2 Spike and Antibodies similarity (1) #47 - Nov 2003 Simian Virus 40 similarity (1) #200 - Aug 2016 Quasisymmetry in Icosahedral Viruses similarity (2)

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Assembly

Deposited unit

A: Major capsid protein L1

D: Major capsid protein L1

G: Major capsid protein L1

J: Major capsid protein L1

M: Major capsid protein L1

P: Major capsid protein L1

S: Major capsid protein L1

V: Major capsid protein L1

Y: Major capsid protein L1

b: Major capsid protein L1

B: Heavy chain of 13H5

C: Light chain of 13H5

E: Heavy chain of 13H5

F: Light chain of 13H5

H: Heavy chain of 13H5

I: Light chain of 13H5

K: Heavy chain of 13H5

L: Light chain of 13H5

N: Heavy chain of 13H5

O: Light chain of 13H5

g: Heavy chain of 13H5

j: Light chain of 13H5

Q: Heavy chain of 13H5

R: Light chain of 13H5

T: Heavy chain of 13H5

U: Light chain of 13H5

W: Heavy chain of 13H5

X: Light chain of 13H5

Z: Heavy chain of 13H5

a: Light chain of 13H5

1.02 MDa, 30 polymers
Search similar-shape structures of this assembly by Omokage search (details)

A: Major capsid protein L1

D: Major capsid protein L1

G: Major capsid protein L1

J: Major capsid protein L1

M: Major capsid protein L1

B: Heavy chain of 13H5

C: Light chain of 13H5

E: Heavy chain of 13H5

F: Light chain of 13H5

H: Heavy chain of 13H5

I: Light chain of 13H5

K: Heavy chain of 13H5

L: Light chain of 13H5

N: Heavy chain of 13H5

O: Light chain of 13H5

defined by author
Evidence: gel filtration
512 kDa, 15 polymers
Search similar-shape structures of this assembly by Omokage search (details)

P: Major capsid protein L1

S: Major capsid protein L1

V: Major capsid protein L1

Y: Major capsid protein L1

b: Major capsid protein L1

g: Heavy chain of 13H5

j: Light chain of 13H5

Q: Heavy chain of 13H5

R: Light chain of 13H5

T: Heavy chain of 13H5

U: Light chain of 13H5

W: Heavy chain of 13H5

X: Light chain of 13H5

Z: Heavy chain of 13H5

a: Light chain of 13H5

defined by author
512 kDa, 15 polymers
Search similar-shape structures of this assembly by Omokage search (details)

Unit cell

Length a, b, c (Å)	139.090, 208.309, 205.948
Angle α, β, γ (deg.)	90.000, 95.610, 90.000
Int Tables number	4
Space group name H-M	P12₁1

Noncrystallographic symmetry (NCS)

NCS domain:
NCS domain segments:

Component-ID: 1

Dom-ID	Ens-ID	Beg auth comp-ID	Beg label comp-ID	End auth comp-ID	End label comp-ID	Selection details	Auth asym-ID	Label asym-ID	Auth seq-ID	Label seq-ID
1	1	LYS	LYS	SER	SER	chain A	A	A	12 - 460	15 - 463
2	1	LYS	LYS	SER	SER	chain D	D	B	12 - 460	15 - 463
3	1	LYS	LYS	SER	SER	chain G	G	C	12 - 460	15 - 463
4	1	LYS	LYS	SER	SER	chain J	J	D	12 - 460	15 - 463
5	1	LYS	LYS	SER	SER	chain M	M	E	12 - 460	15 - 463
6	1	LYS	LYS	SER	SER	chain P	P	F	12 - 460	15 - 463
7	1	LYS	LYS	SER	SER	chain S	S	G	12 - 460	15 - 463
8	1	LYS	LYS	SER	SER	chain V	V	H	12 - 460	15 - 463
9	1	LYS	LYS	SER	SER	chain Y	Y	I	12 - 460	15 - 463
10	1	LYS	LYS	SER	SER	chain b	b	J	12 - 460	15 - 463
1	2	GLU	GLU	VAL	VAL	chain B	B	K	1 - 218	1 - 218
2	2	GLU	GLU	VAL	VAL	chain E	E	M	1 - 218	1 - 218
3	2	GLU	GLU	VAL	VAL	chain H	H	O	1 - 218	1 - 218
4	2	GLU	GLU	VAL	VAL	chain K	K	Q	1 - 218	1 - 218
5	2	GLU	GLU	VAL	VAL	chain N	N	S	1 - 218	1 - 218
6	2	GLU	GLU	VAL	VAL	chain Q	Q	W	1 - 218	1 - 218
7	2	GLU	GLU	VAL	VAL	chain T	T	Y	1 - 218	1 - 218
8	2	GLU	GLU	VAL	VAL	chain W	W	AA	1 - 218	1 - 218
9	2	GLU	GLU	VAL	VAL	chain Z	Z	CA	1 - 218	1 - 218
10	2	GLU	GLU	VAL	VAL	chain g	g	U	1 - 218	1 - 218
1	3	ASP	ASP	CYS	CYS	chain C	C	L	1 - 214	1 - 214
2	3	ASP	ASP	CYS	CYS	chain F	F	N	1 - 214	1 - 214
3	3	ASP	ASP	CYS	CYS	chain I	I	P	1 - 214	1 - 214
4	3	ASP	ASP	CYS	CYS	chain L	L	R	1 - 214	1 - 214
5	3	ASP	ASP	CYS	CYS	chain O	O	T	1 - 214	1 - 214
6	3	ASP	ASP	CYS	CYS	chain R	R	X	1 - 214	1 - 214
7	3	ASP	ASP	CYS	CYS	chain U	U	Z	1 - 214	1 - 214
8	3	ASP	ASP	CYS	CYS	chain X	X	BA	1 - 214	1 - 214
9	3	ASP	ASP	CYS	CYS	chain a	a	DA	1 - 214	1 - 214
10	3	ASP	ASP	CYS	CYS	chain j	j	V	1 - 214	1 - 214

NCS ensembles :

ID
1
2
3

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Components

#1: Protein	Major capsid protein L1 Mass: 55098.113 Da / Num. of mol.: 10 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Human papillomavirus type 6 / Gene: L1 / Production host: Escherichia coli (E. coli) / References: UniProt: Q9W9C6
#2: Antibody	Heavy chain of 13H5 Mass: 23721.373 Da / Num. of mol.: 10 / Source method: isolated from a natural source / Source: (natural) Mus musculus (house mouse)
#3: Antibody	Light chain of 13H5 Mass: 23601.086 Da / Num. of mol.: 10 / Source method: isolated from a natural source / Source: (natural) Mus musculus (house mouse)
Has protein modification	Y

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Experimental details

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Experiment

Experiment	Method: X-RAY DIFFRACTION / Number of used crystals: 1

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Sample preparation

Crystal	Density Matthews: 2.9 Å³/Da / Density % sol: 57.57 %
Crystal grow	Temperature: 293.15 K / Method: vapor diffusion / Details: 0.1M Hepes pH 7.0, 8.2% PEG 20000

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Data collection

Diffraction	Mean temperature: 123.15 K / Serial crystal experiment: N
Diffraction source	Source: SYNCHROTRON / Site: SSRF / Beamline: BL17U1 / Wavelength: 0.9795 Å
Detector	Type: DECTRIS PILATUS 2M / Detector: PIXEL / Date: Oct 20, 2013
Radiation	Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
Radiation wavelength	Wavelength: 0.9795 Å / Relative weight: 1
Reflection	Resolution: 3.6→50 Å / Num. obs: 133760 / % possible obs: 99.9 % / Redundancy: 3.8 % / R_sym value: 0.306 / Net I/σ(I): 5.1
Reflection shell	Resolution: 3.61→3.67 Å / Num. unique obs: 12913 / R_sym value: 0.955 / % possible all: 99.9

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Processing

Software

Name	Version	Classification
HKL-2000		data scaling
PHENIX	1.15.2_3472	refinement
PDB_EXTRACT	3.27	data extraction
HKL-2000		data reduction
PHASER		phasing

Refinement

Method to determine structure:

MOLECULAR REPLACEMENT
Starting model: 1PLG, 5Y9E

1plg

5y9e

Resolution: 3.606→49.019 Å / SU ML: 0.55 / Cross valid method: THROUGHOUT / σ(F): 1.35 / Phase error: 30.82 / Stereochemistry target values: ML

	R_factor	Num. reflection	% reflection
R_free	0.293	6718	5.03 %
R_work	0.2522	126901	-
obs	0.2542	133619	99.46 %

Solvent computation

Shrinkage radii: 0.9 Å / VDW probe radii: 1.11 Å / Solvent model: FLAT BULK SOLVENT MODEL

Displacement parameters

B_iso max: 277.92 Å² / B_iso mean: 85.4272 Å² / B_iso min: 22.55 Å²

Refinement step

Cycle: final / Resolution: 3.606→49.019 Å

	Protein	Nucleic acid	Ligand	Solvent	Total
Num. atoms	65550	0	0	0	65550
Num. residues	-	-	-	-	8470

Refine LS restraints NCS

Ens-ID	Dom-ID	Auth asym-ID	Number	Refine-ID	Rms	Type
1	1	A	20081	X-RAY DIFFRACTION	10.265	TORSIONAL
1	2	D	20081	X-RAY DIFFRACTION	10.265	TORSIONAL
1	3	G	20081	X-RAY DIFFRACTION	10.265	TORSIONAL
1	4	J	20081	X-RAY DIFFRACTION	10.265	TORSIONAL
1	5	M	20081	X-RAY DIFFRACTION	10.265	TORSIONAL
1	6	P	20081	X-RAY DIFFRACTION	10.265	TORSIONAL
1	7	S	20081	X-RAY DIFFRACTION	10.265	TORSIONAL
1	8	V	20081	X-RAY DIFFRACTION	10.265	TORSIONAL
1	9	Y	20081	X-RAY DIFFRACTION	10.265	TORSIONAL
1	10	b	20081	X-RAY DIFFRACTION	10.265	TORSIONAL
2	1	B	10036	X-RAY DIFFRACTION	10.265	TORSIONAL
2	2	E	10036	X-RAY DIFFRACTION	10.265	TORSIONAL
2	3	H	10036	X-RAY DIFFRACTION	10.265	TORSIONAL
2	4	K	10036	X-RAY DIFFRACTION	10.265	TORSIONAL
2	5	N	10036	X-RAY DIFFRACTION	10.265	TORSIONAL
2	6	Q	10036	X-RAY DIFFRACTION	10.265	TORSIONAL
2	7	T	10036	X-RAY DIFFRACTION	10.265	TORSIONAL
2	8	W	10036	X-RAY DIFFRACTION	10.265	TORSIONAL
2	9	Z	10036	X-RAY DIFFRACTION	10.265	TORSIONAL
2	10	g	10036	X-RAY DIFFRACTION	10.265	TORSIONAL
3	1	C	10285	X-RAY DIFFRACTION	10.265	TORSIONAL
3	2	F	10285	X-RAY DIFFRACTION	10.265	TORSIONAL
3	3	I	10285	X-RAY DIFFRACTION	10.265	TORSIONAL
3	4	L	10285	X-RAY DIFFRACTION	10.265	TORSIONAL
3	5	O	10285	X-RAY DIFFRACTION	10.265	TORSIONAL
3	6	R	10285	X-RAY DIFFRACTION	10.265	TORSIONAL
3	7	U	10285	X-RAY DIFFRACTION	10.265	TORSIONAL
3	8	X	10285	X-RAY DIFFRACTION	10.265	TORSIONAL
3	9	a	10285	X-RAY DIFFRACTION	10.265	TORSIONAL
3	10	j	10285	X-RAY DIFFRACTION	10.265	TORSIONAL

LS refinement shell

Refine-ID: X-RAY DIFFRACTION / R_factor R_free error: 0

Resolution (Å)	R_factor R_free	Num. reflection R_free	R_factor R_work	Num. reflection R_work	% reflection obs (%)
3.606-3.6467	0.3495	219	0.3388	3773	89
3.6467-3.6895	0.3771	240	0.3524	4216	100
3.6895-3.7345	0.3952	200	0.3398	4264	100
3.7345-3.7818	0.3326	218	0.319	4232	100
3.7818-3.8315	0.3476	244	0.3072	4200	100
3.8315-3.884	0.3798	250	0.3162	4239	100
3.884-3.9395	0.3836	225	0.3226	4236	100
3.9395-3.9982	0.3629	226	0.3242	4207	100
3.9982-4.0607	0.358	224	0.3101	4245	100
4.0607-4.1272	0.3671	229	0.3053	4237	100
4.1272-4.1983	0.3264	213	0.2895	4225	100
4.1983-4.2746	0.332	198	0.276	4241	100
4.2746-4.3568	0.3212	210	0.2716	4278	100
4.3568-4.4457	0.3075	215	0.273	4212	100
4.4457-4.5423	0.2861	255	0.2374	4216	100
4.5423-4.6479	0.2856	242	0.2396	4254	100
4.6479-4.764	0.2828	201	0.2179	4212	100
4.764-4.8927	0.231	244	0.2159	4234	100
4.8927-5.0365	0.2778	232	0.2189	4247	100
5.0365-5.1989	0.2602	211	0.2135	4272	100
5.1989-5.3845	0.2756	212	0.2255	4230	100
5.3845-5.5998	0.2829	237	0.226	4250	100
5.5998-5.8543	0.2913	210	0.2425	4264	100
5.8543-6.1624	0.2717	215	0.2358	4244	100
6.1624-6.5476	0.2765	226	0.2357	4269	100
6.5476-7.0518	0.2853	232	0.2205	4261	100
7.0518-7.759	0.2648	230	0.2243	4257	100
7.759-8.876	0.2278	223	0.185	4286	100
8.876-11.161	0.1934	216	0.1766	4293	100
11.161-49.019	0.2451	221	0.2451	4307	98

Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

ID	L11 (°²)	L12 (°²)	L13 (°²)	L22 (°²)	L23 (°²)	L33 (°²)	S11 (Å °)	S12 (Å °)	S13 (Å °)	S21 (Å °)	S22 (Å °)	S23 (Å °)	S31 (Å °)	S32 (Å °)	S33 (Å °)	T11 (Å²)	T12 (Å²)	T13 (Å²)	T22 (Å²)	T23 (Å²)	T33 (Å²)	Origin x (Å)	Origin y (Å)	Origin z (Å)
1	0.041	0.0576	0.0075	0.3125	-0.0886	0.2905	-0.2423	0.3376	-0.3427	-0.3232	-0.2593	0.0788	0.229	-0.2407	-0.4571	0.3641	-0.0485	0.0421	0.4588	-0.2021	0.4949	-78.4193	17.5281	-87.8262
2	0.3581	-0.1386	-0.195	0.2006	0.0032	0.1581	-0.0317	0.76	-0.1514	-0.1234	-0.0613	-0.0983	0.0894	-0.2749	-0.3634	0.2159	0.1652	0.071	0.3673	-0.5308	0.6477	-78.4324	22.1104	-89.2348
3	0.117	0.1283	-0.133	0.0744	-0.1181	0.1899	0.0906	0.0593	0.0817	-0.1015	-0.1358	-0.0292	-0.2711	0.5628	-0.032	0.3113	0.0973	0.1458	0.5035	-0.0417	0.5092	-55.2582	34.8641	-78.525
4	0.5064	-0.3142	0.2587	0.2561	-0.0727	0.4449	0.0106	0.5302	0.0071	-0.4186	-0.0838	-0.3238	-0.085	0.2206	-0.6203	0.469	-0.0419	0.1791	0.4256	-0.2219	0.3734	-57.7337	35.9782	-82.0123
5	0.3071	0.2683	-0.1578	0.33	-0.146	0.0734	0.0024	0.0718	-0.4285	0.066	-0.2507	-0.1897	0.1244	0.031	-0.3816	0.3058	0.0283	0.0941	0.4928	-0.2781	0.2808	-78.5304	25.3626	-80.0405
6	0.0035	0.0022	-0.0004	0.0112	0.0085	0.0065	0.0461	-0.0576	0.0243	-0.0462	0.098	-0.0726	-0.0118	0.0335	0	1.226	-0.2527	-0.1695	0.6817	-0.2928	0.9595	-72.9089	8.2228	-108.7874
7	0.0143	0.0117	0.0178	0.0152	0.053	0.0681	0.1161	0.0435	0.0419	-0.0762	-0.0285	-0.0546	-0.0559	-0.1301	0.1532	0.8062	-0.1275	-0.0398	0.6137	-0.3916	0.6356	-86.6624	17.8808	-90.7751
8	0.2012	0.055	0.0399	0.0712	0.1364	0.202	0.1816	0.3473	-0.214	-0.1444	0.0331	0.0256	0.1006	0.1849	0.1018	0.8566	0.032	0.1266	0.5829	-0.1034	0.3156	-53.192	44.08	-107.6894
9	0.3641	-0.0796	0.4694	0.1054	-0.1223	0.5987	-0.401	0.1517	0.3131	-0.1933	-0.0714	0.002	-0.3089	-0.0669	-0.5391	0.764	0.041	0.1546	0.5183	-0.0752	0.3107	-53.0023	56.449	-93.1762
10	-0.013	-0.0598	0.0386	0.1259	-0.0374	-0.0029	-0.0508	0.0981	0.2837	-0.5525	0.0306	-0.2791	-0.5748	0.0528	-0.0215	0.6595	-0.0063	0.1164	0.5186	0.0478	0.2565	-55.524	60.825	-91.7499
11	0.0708	0.0977	0.0583	0.0674	0.0134	0.2026	0.16	0.148	0.0389	-0.6144	0.06	-0.2525	-0.2265	0.0758	0.0276	0.5163	0.1213	0.0854	0.4866	-0.0284	0.2837	-51.97	37.7052	-88.7892
12	0.0055	0.0066	-0.0015	0.0112	0.0061	0.0078	-0.1654	-0.0471	-0.0633	0.0441	-0.1695	-0.0573	0.0594	0.059	0	1.218	0.1055	0.073	1.021	-0.0213	0.5636	-51.3386	56.3075	-127.8224
13	0.0301	-0.0365	0.0003	0.0404	-0.0165	0.0379	0.3323	0.0926	0.0994	-0.2906	-0.0499	-0.0175	0.122	0.1429	0	1.2535	0.0843	0.0419	0.9155	-0.1702	0.4758	-59.0261	39.0866	-111.9544
14	0.1705	0.1537	-0.1199	0.3035	-0.253	0.1674	0.1579	0.0908	-0.0525	-0.3845	-0.1307	-0.0456	-0.2671	0.1999	0.2141	0.8702	-0.079	0.08	0.4253	0.1558	0.3502	-68.4323	81.5483	-100.4384
15	0.2816	-0.0922	-0.1035	0.0446	0.0661	0.0826	-0.3186	0.0745	0.2181	0.0934	0.0892	-0.1901	0.1421	-0.1267	0.0531	1.0824	0.047	0.0799	0.1565	0.1235	0.3302	-66.5115	71.4638	-68.4544
16	0.1722	0.0298	-0.0301	0.017	-0.0018	-0.0008	0.0133	-0.1963	0.2368	-0.1101	0.2638	-0.0596	-0.2423	-0.0613	0.0029	0.6858	0.0589	-0.0067	0.3072	0.0751	0.5	-75.653	88.4221	-76.2809
17	0.0734	-0.1147	-0.0414	0.1063	0.0744	0.0329	-0.0855	0.1049	0.1465	0.0357	-0.1371	-0.2194	-0.0878	-0.2981	-0.0001	0.6675	-0.0314	-0.0179	0.4487	0.0562	0.4373	-75.0958	78.7459	-75.548
18	0.5884	-0.1455	0.0622	0.0482	0.117	0.2053	0.0858	0.2178	0.1792	0.0525	-0.1371	0.4565	-0.2143	-0.0384	-0.0029	0.6037	0.0181	-0.0069	0.3072	0.0615	0.4625	-76.1005	71.2741	-81.8459
19	0.1284	0.1058	-0.1608	0.183	-0.0393	0.1528	-0.0226	0.1994	-0.0691	-0.4451	0.044	-0.1185	0.0205	0.2143	0.0101	0.6507	0.023	0.0119	0.4262	0.0771	0.351	-58.0899	74.2842	-91.692
20	0.061	-0.1108	-0.0412	0.3529	0.1569	0.0646	0.0198	-0.0713	0.0816	0.186	0.1861	-0.0921	-0.1263	-0.0519	0.0811	1.3454	-0.025	-0.2334	0.7869	0.192	0.2837	-83.4008	98.1794	-108.9524
21	0.0045	-0.039	-0.0058	0.0587	0.0009	0.004	0.0349	0.2401	-0.0207	-0.1818	-0.0206	-0.1135	0.0381	-0.0032	0.0013	1.0447	0.1251	0.1208	0.7457	0.1588	0.4147	-68.3469	78.6407	-108.6823
22	0.0643	-0.0659	-0.0714	0.1616	0.0796	0.1372	0.2544	0.1445	-0.053	-0.1293	0.1272	0.0972	-0.1113	-0.1718	0.1208	0.7614	0.1276	-0.1262	0.3926	0.133	0.4916	-101.2048	80.2184	-76.858
23	0.3263	0.0935	-0.1983	0.327	0.1059	0.4702	0.0815	0.5453	0.1091	0.0534	0.0204	0.2208	0.0153	-0.3625	-0.0239	0.5772	0.3422	-0.0516	-0.0271	-0.0901	0.3778	-99.8001	75.9113	-78.4919
24	0.0831	0.0518	-0.1088	0.0234	-0.064	0.0923	0.0666	-0.1037	-0.0047	-0.1932	-0.2411	-0.019	-0.2727	-0.2159	-0.0046	0.5346	0.0081	0.0768	0.2391	-0.0201	0.6004	-79.8024	60.6533	-58.3027
25	0.0078	0.0234	0.0328	0.0429	0.063	0.0766	-0.0747	-0.2765	0.1004	0.1965	-0.179	0.1937	0.4384	-0.3219	-0.0017	0.4103	0.0569	0.0336	0.3626	0.0073	0.3065	-97.1593	63.9781	-55.9145
26	0.218	-0.0274	-0.2296	0.0577	-0.2342	0.3927	-0.1245	-0.1216	0.0015	-0.1683	0.043	-0.0037	-0.0604	-0.1425	-0	0.5583	0.0669	-0.1064	0.4037	-0.0142	0.4672	-89.8769	66.7082	-69.394
27	0.0086	0.0094	-0.0087	0.0016	-0.005	0.0125	0.0077	0.0387	-0.0408	0.1318	0.0716	0.0306	-0.0605	0.0682	0	0.5111	-0.0846	-0.1098	1.0623	-0.0219	0.6724	-124.3934	76.3464	-77.9863
28	0.1073	0.0304	0.0829	0.0223	0.0279	0.0469	-0.3023	0.1714	0.1991	-0.0346	0.0813	0.25	0.0304	0.1542	-0.0063	0.7482	0.1996	-0.0172	0.6208	-0.0937	0.6104	-101.5972	82.044	-85.4779
29	0.1666	0.2481	0.1094	0.2187	0.141	0.1051	-0.2535	-0.0037	0.0147	-0.329	-0.0154	0.1608	-0.3758	-0.0305	-0.0334	0.0864	-0.0217	-0.073	0.4604	-0.06	0.3633	-106.9293	40.1282	-70.0949
30	0.062	-0.0949	-0.0081	0.0946	0.0332	0.009	0.1963	0.1869	-0.0277	-0.0137	0.1102	-0.0846	0.0217	-0.1582	0.0166	0.2693	-0.0128	-0.0055	0.4535	0.0027	0.362	-74.8629	41.4401	-60.1896
31	0.081	-0.0627	0.1315	0.0578	-0.0389	0.1189	0.2225	-0.0284	-0.3555	-0.249	0.1311	0.2863	0.2201	-0.0764	0.0226	0.3548	0.0101	-0.0051	0.3204	-0.0705	0.3482	-88.443	27.5265	-64.7931
32	0.2906	0.2518	-0.3967	0.3869	-0.3874	0.5409	-0.2107	-0.0536	-0.1892	-0.081	-0.3264	-0.0849	0.3086	0.1044	-0.4355	0.4156	-0.0282	-0.1294	0.3447	-0.1388	0.3261	-73.0629	37.9377	-66.9461
33	0.1764	0.1133	-0.1414	0.1155	-0.112	0.0878	0.1113	0.1036	0.1015	-0.0319	0.1509	0.0552	-0.0595	-0.1275	0.2439	0.4522	0.0337	-0.13	0.3585	-0.0855	0.3868	-99.8439	46.7789	-66.3665
34	0.0146	0.0052	-0.0005	0.0025	0.0014	0.0021	-0.0365	-0.0816	-0.1391	0.0661	-0.0567	0.1436	-0.0158	0.0005	-0	0.7319	-0.1262	-0.2252	1.2392	-0.1255	0.8918	-118.1205	20.7054	-78.2224
35	0.0358	0.0341	-0.0085	0.0386	0.0044	0.0427	-0.0462	-0.0494	-0.1368	-0.2139	-0.1264	-0.1533	-0.25	-0.2329	0.0006	0.413	0.0545	0.0354	0.6471	0.0714	0.6361	-112.9808	44.5015	-74.5269
36	0.0096	-0.1435	-0.0464	0.0876	0.0612	0.0291	0.2735	-0.457	-0.3847	0.1839	-0.1835	0.1202	0.0012	0.1053	0.0255	0.0945	0.8335	-0.4225	-0.1534	0.699	0.2255	5.128	-81.2246	-8.4331
37	0.0625	0.0296	-0.0237	0.0691	0.025	0.0259	0.0944	0.0027	-0.0064	-0.0413	-0.0754	0.0289	-0.0414	-0.1689	0.031	0.3107	0.3045	-0.0882	0.5784	-0.0229	0.5333	-11.4616	-61.1681	-29.6914
38	0.0049	-0.0321	-0.0107	0.0446	0.0336	0.0135	-0.1073	0.0418	0.0856	-0.2353	-0.2799	-0.212	0.0218	-0.0466	-0.0105	0.3434	0.1392	0.071	0.7203	0.1512	0.6401	-23.3521	-76.869	-14.3748
39	0.1657	0.1073	-0.0087	0.1036	0.0806	0.025	-0.0765	-0.2107	0.0658	-0.1467	-0.016	0.0027	0.1231	0.0559	-0.0001	0.3323	0.1042	-0.033	0.4129	0.1364	0.3668	-14.5992	-65.9428	-19.7943
40	0.3899	0.1694	0.0494	0.3851	0.1609	0.0636	0.1545	-0.0203	0.1414	-0.0065	-0.1491	0.0714	0.211	0.0407	-0.0079	0.3661	0.1656	-0.0866	0.4859	0.2076	0.4652	6.8806	-74.7569	-16.3174
41	0.031	-0.0001	-0.0223	0.0187	0.0338	0.0952	0.0795	-0.0224	0.029	-0.0812	0.0339	0.0102	0.0028	0.0368	0.0885	0.9345	0.047	-0.2832	0.1095	0.1954	1.0562	-4.6528	-93.0868	9.8271
42	0.0311	-0.0363	-0.0382	0.0531	0.0045	0.0767	0.0196	0.1511	0.0146	0.3059	-0.0338	0.2554	0.2208	0.271	-0	0.4516	0.1629	0.078	0.7043	0.2391	0.8151	12.4754	-81.8557	-3.8494
43	0.3107	0.0883	-0.2256	0.0164	-0.0301	0.487	-0.4767	-0.2484	-0.5194	0.0775	0.1626	0.1699	0.0964	-0.1313	-0.4722	0.3854	-0.044	0.075	0.5413	0.3836	0.4037	-24.7661	-57.9814	3.6634
44	0.2474	-0.0606	0.1845	0.2203	-0.1544	0.2308	-0.0752	-0.0736	-0.0054	-0.1085	-0.0826	0.314	-0.4381	0.0723	-0.142	0.4743	0.16	-0.0224	0.3164	0.0742	0.2902	-24.8632	-39.2814	-19.2938
45	0.2396	-0.0635	0.1534	0.1833	-0.103	0.095	0.0304	-0.0471	0.0048	-0.057	-0.079	0.1058	0.1276	0.1494	-0.0094	0.2297	0.0666	0.0216	0.4641	0.0779	0.3553	-21.4916	-47.1894	-11.7998
46	0.0251	0.0018	0.0159	0.0383	0.0142	0.0129	0.0371	0.0734	0.045	0.0651	0.1358	0.0844	0.023	0.0493	0.0603	0.8196	0.1187	-0.0013	1.1831	0.4921	0.5811	-34.0216	-47.2655	22.9963
47	0.0202	0.0004	-0.0037	0.0464	0.01	0.0278	0.1314	-0.128	0.112	-0.1687	-0.1517	-0.1566	0.0197	-0.2323	-0	0.6523	0.1621	0.0705	0.7497	0.2332	0.5765	-21.2696	-63.4765	9.4889
48	0.1434	-0.1349	-0.1021	0.0959	0.0866	0.1217	-0.0783	-0.1796	0.0006	0.0754	-0.2303	-0.1025	-0.037	-0.1663	-0.0109	0.2778	0.0212	-0.0544	0.3225	0.0188	0.3358	-14.3355	-18.9586	1.0956
49	0.3863	-0.0184	0.0479	0.6495	-0.2973	0.8198	0.2414	-0.1426	0.1111	0.521	-0.3036	0.003	-0.3927	-0.0103	-0.3531	-0.0907	0.6123	0.0922	0.2406	-0.1887	0.3862	-10.6778	-22.0188	0.4868
50	0.1113	-0.0592	-0.0479	0.1276	0.0503	0.0627	-0.3879	-0.0475	-0.0734	-0.257	-0.0941	-0.1272	-0.4829	0.3805	-0.0577	0.3762	0.0094	-0.102	0.5521	0.0509	0.4254	-2.6398	-21.3154	-26.8917
51	0.0085	-0.0404	-0.0082	0.0671	0.0039	0.0041	-0.1077	-0.3153	0.1984	-0.0273	-0.1446	-0.2533	-0.1668	-0.058	-0	0.2299	0.0113	-0.0158	0.5508	0.0301	0.4125	-5.3014	-16.4452	-23.3642
52	0.0481	0.031	-0.0558	0.0854	0.0346	0.0124	0.0916	-0.3539	0.059	-0.1769	-0.2777	-0.1034	-0.1695	0.2395	-0.01	0.3427	0.0136	0.014	0.5624	0.025	0.4034	3.8844	-23.6666	-24.6027
53	0.1771	0.0044	-0.0402	0.0089	0.0036	0.0272	-0.2006	-0.2677	0.0233	0.2599	-0.2205	-0.0069	-0.135	0.1621	-0.0615	0.488	0.0135	-0.1235	0.6131	0.0254	0.2938	-3.8325	-26.9638	-2.3988
54	0.136	-0.0556	0.0552	0.0249	-0.0458	0.0788	-0.0215	-0.0936	-0.019	0.1029	0.2444	0.1299	-0.1276	-0.1191	0.1803	0.0767	0.0046	-0.1198	0.4444	-0.0031	0.3064	-22.8465	-30.3015	-12.9869
55	0.0127	0.0149	-0.016	0.0136	-0.0184	0.0135	0.0197	0.0293	0.1072	-0.0264	0.1589	0.1535	-0.0598	-0.003	0	0.9616	0.1607	-0.1827	1.3759	-0.1803	0.6112	-2.4068	-2.3475	12.8591
56	0.0493	0.0322	-0.0231	0.0359	0.0159	0.018	-0.0827	-0.1291	0.2015	0.0716	0.0857	-0.1109	0.1918	-0.116	-0	0.5177	0.1177	0.0325	0.7927	0.022	0.5228	-15.0026	-23.1673	8.7447
57	0.3553	0.0803	0.2449	0.5375	-0.0715	0.2266	0.025	-0.1215	0.4611	-0.1698	-0.2276	-0.6915	0.015	0.0165	-0.0264	0.1732	-0.2128	-0.2644	0.4634	0.1784	1.0152	24.2908	-19.8275	-12.8449
58	0.2013	0.4743	-0.0171	1.1953	-0.057	0.0127	0.3011	0.2456	-0.0838	0.3178	-0.1962	0.0153	-0.0544	-0.0794	0.0212	0.2191	0.203	-0.037	0.725	0.0169	0.3654	10.6999	-38.8892	-36.8891
59	0.0012	0.0066	-0.0011	0.176	-0.1428	0.287	0.0086	-0.1376	-0.0851	-0.208	0.1167	0.0725	0.0969	-0.0437	0.0458	0.4365	0.141	0.1683	0.9181	0.3338	0.8802	35.4729	-36.7136	-34.1722
60	0.2743	-0.0603	0.109	0.3669	0.1133	0.1839	0.0835	0.2304	0.2664	-0.4334	-0.2307	-0.4468	0.0303	0.0743	-0.1251	-0.4081	0.0119	-0.0989	0.6648	0.1591	0.5257	18.5876	-32.5695	-25.983
61	0.0119	-0.0145	-0.0121	0.0076	0.0116	0.0135	0.0457	-0.0047	-0.0493	-0.1502	-0.1218	-0.1559	-0.1179	-0.1186	-0	0.7845	-0.4252	-0.2234	1.3092	0.0593	1.0517	47.1737	-20.3241	-5.9926
62	0.1652	-0.0347	0.0624	0.0572	-0.0041	0.0526	-0.2946	-0.1346	0.2144	0.1068	-0.0105	-0.0705	-0.1649	-0.0574	-0.019	0.5669	-0.1433	-0.2274	0.5423	-0.1144	0.9905	22.8397	-16.6025	-4.89
63	0.0964	-0.1775	-0.1423	0.2268	0.2166	0.1646	0.0757	-0.1725	0.2617	-0.0111	-0.1253	-0.3561	-0.1576	0.1071	0.0138	0.2659	-0.0392	-0.0546	0.764	0.1364	0.6756	37.0541	-57.735	-19.3503
64	0.2186	0.0266	-0.2399	0.1131	-0.0429	0.1707	0.1141	0.1542	-0.2793	0.0897	-0.0325	-0.4398	0.1378	0.0901	-0.1225	-0.0592	0.3055	-0.0877	0.9022	0.3273	0.8592	32.8896	-57.426	-16.9517
65	0.1673	0.1014	-0.0517	0.1374	-0.0592	0.0109	0.0701	-0.0275	0.0612	-0.2903	-0.0393	0.0083	0.0948	0.2012	0.0257	0.4758	0.2425	0.2316	0.5742	0.0843	0.7034	7.1588	-58.4467	-36.3284
66	0.2677	0.2017	-0.0862	0.5673	0.2837	0.2824	0.2662	0.0711	-0.1073	-0.1965	0.12	0.1464	0.3638	-0.1043	0.2476	0.6224	0.2425	-0.0692	0.3039	0.2492	0.5863	19.491	-79.2961	-30.1039
67	0.0173	0.0549	0.0716	0.2311	0.1681	0.1792	0.0287	-0.0122	-0.1186	0.2107	-0.1958	-0.1945	0.1008	-0.1196	-0.4106	0.4877	0.335	-0.047	0.6996	0.3559	0.489	18.1074	-66.487	-26.8907
68	0.0053	-0.0001	-0.0152	0.0233	0.0231	0.0154	-0.0664	-0.043	0.0728	-0.2157	-0.1493	0.406	-0.1809	0.395	-0.0001	0.4864	0.198	-0.0258	0.5777	0.0074	0.6412	-7.2195	-73.1802	-41.9682
69	0.0834	-0.0339	-0.0407	0.0476	0.0078	0.0338	0.4124	-0.1581	-0.0875	0.0362	-0.0829	-0.2402	0.145	0.1935	0.2261	0.2357	0.228	-0.1896	0.6927	0.3811	0.6228	24.4371	-57.7816	-13.9773
70	0.0663	0.0772	0.0743	0.0612	0.0611	0.0328	0.0625	-0.1129	-0.2154	0.0054	-0.0971	-0.1337	-0.0145	-0.0674	0.0469	0.2299	0.3889	0.0525	0.7884	0.4733	0.8708	27.5446	-45.5923	-32.1026
71	0.0102	-0.0032	0.0097	0.0056	0.0043	0.0052	0.0782	0.1599	0.0749	-0.0038	-0.1801	-0.2032	0.0944	-0.1427	-0	0.2661	-0.0097	-0.143	0.8609	0.1665	0.7666	45.7537	-76.3155	-7.9532
72	0.4084	-0.0973	-0.3085	0.4006	0.1287	0.2789	0.4174	0.1432	-0.0231	-0.1183	0.0469	0.0601	0.1782	0.3602	0.3672	0.4085	0.1456	-0.3603	0.8035	0.4409	0.9631	39.8934	-52.901	-12.5661
73	0.0715	0.0474	0.1157	0.1825	0.1366	0.156	0.0082	0.1634	0.0118	0.0481	0.133	-0.1034	0.2331	0.0428	0.028	0.2113	-0.178	0.0033	0.2265	-0.0463	0.794	-47.9429	6.0916	-40.6572
74	0.0188	0.0008	-0.0464	0.2188	-0.1512	0.3045	-0.2003	-0.0754	-0.0961	0.0071	-0.2323	0.0215	-0.0523	-0.1057	-0.3844	0.1816	0.0621	0.0276	0.1921	-0.218	0.983	-53.9172	15.8641	-43.2581
75	0.1224	0.0151	-0.054	0.0425	0.0237	0.0938	-0.0802	0.125	-0.0039	0.0416	0.066	-0.2732	0.1781	-0.0511	0.0349	0.356	-0.283	-0.0314	0.0765	0.128	0.3326	-46.7819	17.5788	-46.9139
76	0.24	-0.019	0.0558	0.0283	0.0019	0.0154	-0.0736	-0.0648	0.0119	0.0408	0.0753	0.0775	0.0302	0.0547	-0.0334	0.1951	0.3447	-0.1425	0.2181	-0.1782	0.6453	-47.5459	14.3299	-36.164
77	0.0973	0.0072	-0.0067	0.0076	-0.0661	0.0892	0.0528	-0.0893	0.1426	0.066	0.0571	-0.0249	0.2119	-0.324	-0.0014	0.3457	-0.0689	0.0587	0.335	-0.0424	0.4696	-48.344	5.1393	-21.1556
78	0.1563	0.0623	-0.1969	0.0468	-0.0765	0.2556	-0.1166	-0.0354	-0.0056	-0.0797	-0.2079	0.0709	0.038	-0.0941	-0.0098	0.2639	-0.0159	-0.1132	0.8344	0.0121	0.4794	-51.2632	-4.59	-16.0917
79	0.1393	0.105	0.0298	0.3726	0.1505	0.3038	-0.0603	0.0245	0.0185	-0.1238	-0.0283	-0.1165	-0.0656	-0.0086	-0.2497	0.6066	-0.2165	-0.0217	0.3194	-0.4017	0.3877	-43.4874	5.52	-15.5654
80	0.0177	-0.0132	-0.0067	0.0025	0.0048	0.012	0.2791	0.1413	-0.1793	0.1297	-0.3095	0.4079	-0.1465	-0.1084	0	0.3521	-0.0292	0.0333	0.509	0.0345	0.4334	-47.7307	-7.7559	-9.6765
81	0.0661	-0.1212	-0.0478	0.1994	0.0828	0.0445	-0.1188	-0.0658	0.1731	0.1265	-0.0519	-0.0542	0.0142	-0.1135	-0.1738	-0.2216	-0.126	0.3143	0.5848	0.0552	0.6708	-56.7261	27.8037	-20.7421
82	0.0026	-0.001	0.0201	0.3227	-0.0478	0.0909	0.0234	-0.1249	-0.052	0.0584	0.0875	-0.1213	-0.141	0.0867	0.0509	0.2999	-0.0352	0.0651	0.0677	0.0933	0.4883	-58.9445	31.2865	-29.0317
83	0.0727	-0.0235	0.015	0.0118	0.0081	0.0268	-0.0221	0.0203	0.1412	-0.0249	-0.0259	0.0858	-0.0053	-0.0364	-0.072	-0.005	-0.096	0.229	0.2175	0.0569	0.5481	-66.5682	22.2011	-32.2138
84	0.0956	-0.0071	-0.012	-0.0002	0.0117	0.0227	-0.1349	-0.0487	0.0942	0.0404	-0.0219	-0.0937	0.1954	-0.0149	-0.0445	0.1305	-0.2291	0.2452	0.5926	-0.0813	0.4835	-63.7454	27.1868	-25.535
85	0.3141	0.0773	-0.1669	0.2939	0.2047	0.3828	0.0503	-0.085	0.1178	0.0591	0.1301	-0.3953	0.1813	0.2397	0.4035	0.1563	-0.0725	-0.0742	0.2364	-0.092	0.3758	-48.4658	11.586	-12.2272
86	0.0055	-0.0048	-0.023	0.005	0.0278	0.0729	-0.0795	0.0517	0.1166	0.0828	-0.1322	-0.2049	0.2021	0.0072	-0.0139	0.2914	0.0442	-0.2196	0.539	0.0078	0.5501	-45.4167	12.9845	-5.1665
87	0.0345	-0.0057	-0.0448	0.0034	0.0051	0.0524	0.0644	0.0179	0.0182	-0.0006	0.072	-0.0942	-0.0757	0.0029	0.034	0.2812	-0.1568	-0.1021	0.9354	-0.1535	0.5594	-34.6912	4.7603	-3.7929
88	0.0244	0.0102	0.0288	0.0003	0.0011	0.0094	0.0504	-0.1973	0.0711	0.0601	-0.0097	-0.0115	-0.0406	0.1963	-0	0.4429	0.198	-0.11	0.7245	-0.0642	0.7021	-41.3106	8.6059	6.0088
89	0.1047	0.0329	0.0082	0.0275	-0.0305	0.0857	0.0092	0.1893	-0.0523	0.0125	-0.209	-0.0426	0.027	0.1064	-0.0334	0.4485	-0.3892	0.4774	0.6858	-0.1871	1.0021	-10.0165	40.7947	-70.2953
90	0.0419	0.0305	-0.0223	0.0482	-0.0081	0.0083	-0.1216	0.061	0.0178	-0.0773	0.0291	-0.553	0.0019	0.1267	-0.0031	0.5456	-0.0627	0.2293	0.6224	-0.1544	0.8176	-21.6004	40.56	-68.0827
91	0.1158	0.0401	-0.0184	0.1348	0.1804	0.3271	-0.0665	-0.0935	-0.0909	-0.0212	-0.1917	0.0783	-0.1166	0.0225	-0.288	0.3546	-0.0138	0.1599	0.6069	0.0215	0.3962	-22.8102	49.4562	-65.5828
92	0.3013	0.0775	0.0115	0.1012	-0.039	0.1911	0.0793	-0.0879	-0.1787	0.0745	0.1516	-0.1666	0.1584	0.2942	0.2028	0.1565	0.1092	0.3053	0.9843	0.2679	1.2397	-6.7893	34.5902	-60.9027
93	0.0269	0.0224	-0.0864	0.0217	-0.1032	0.5214	-0.0972	0.062	-0.0193	-0.085	0.0545	0.1415	0.4376	0.1685	-0.0194	0.5634	0.4416	-0.1783	1.5213	-0.0635	1.4561	7.3022	21.5327	-55.9359
94	0.0188	0.0086	0.0335	0.1899	0.0054	0.1072	-0.1205	-0.1854	-0.2175	0.0799	-0.0443	-0.2966	0.0441	0.3258	-0.1803	-0.3555	-0.0317	0.3155	0.2143	0.0764	0.5441	-28.9552	30.4863	-50.9
95	0.0539	0.0055	0.0708	-0.0017	0.0003	0.0749	0.1322	0.0183	0.1676	-0.1228	0.0364	0.0726	-0.1643	0.1871	0.0491	0.514	-0.0867	0.052	0.2186	-0.0109	0.5792	-25.305	32.8037	-52.952
96	0.0074	0.0004	-0.0037	-0.0013	-0.0022	0.0023	0.0647	-0.0579	0.0268	0.0453	0.0393	0.0772	-0.0278	0.0823	-0.0001	1.0111	0.1914	-0.08	0.8668	0.1761	1.0996	-13.2277	18.2578	-40.7912
97	0.0208	-0.0011	0.0252	0.0089	-0.0011	0.0126	0.0215	-0.1087	0.0723	0.2521	0.0814	0.188	0.0274	0.0661	0	1.0031	0.0649	0.0764	1.8959	-0.0143	0.9577	8.2664	24.5255	-41.2865
98	0.0268	-0.0256	-0.0227	0.0168	0.0193	0.0126	-0.0093	-0.1352	-0.148	0.0623	0.0121	0.2099	-0.0148	0.1378	-0	0.7677	0.2291	-0.1214	1.0023	-0.096	1.1192	1.3194	26.9666	-41.0523
99	0.0077	0.0049	0.0117	-0.002	-0.0006	0.0334	0.0941	-0.0663	0.146	0.0004	0.1272	-0.2399	0.0287	-0.1749	0.0001	0.7419	-0.1748	-0.0437	1.1852	-0.0455	1.0022	13.8473	30.4927	-41.5807
100	0.0044	0.0065	0.0094	-0.0019	0.0109	0.0142	-0.0038	0.009	-0.0001	0.0795	-0.0594	0.0328	0.0128	0.0431	-0	0.8951	0.0999	0.0288	1.9226	0.0103	1.2565	11.3515	21.997	-32.7803
101	0.0048	0.0168	-0.0121	0.0326	-0.0305	0.0241	-0.0909	0.0825	-0.0707	-0.019	-0.2468	-0.0072	-0.0238	0.1017	0	1.1401	-0.1101	0.0918	0.6825	-0.0008	0.7455	-27.408	97.1466	-61.9362
102	0.1905	0.0307	-0.23	-0.0005	-0.032	0.2821	0.2311	-0.1567	0.0654	-0.097	-0.2744	0.0255	-0.2685	0.2312	-0.0615	1.1865	-0.1615	0.0094	0.4306	-0.1097	0.6182	-32.5013	86.6365	-63.7495
103	0.0138	0.006	0.012	0.0505	0.0296	0.0363	-0.0197	0.1166	0.1069	-0.0286	0.0156	-0.006	0.0968	-0.0996	-0.1451	0.4724	-0.2512	0.2205	0.1412	0.2921	0.3477	-38.967	87.038	-57.0403
104	0.002	-0.0004	-0.0039	0.0117	0	0.0043	-0.0658	0.1216	0.002	-0.0108	0.0531	0.0063	0.0324	-0.0262	0	0.7989	-0.1706	-0.0039	0.6247	0.0657	0.8367	-36.308	95.8507	-62.0944
105	0.0043	-0.0042	-0.0055	0.0017	0.0119	0.0029	-0.0158	0.1667	-0.1512	0.0904	-0.0917	-0.054	-0.0587	-0.0885	0.0001	0.82	0.035	-0.1753	0.5041	0.1535	0.7079	-27.0752	89.7183	-56.3007
106	0.0866	-0.0884	-0.0046	0.0683	0.0085	0.2165	0.1517	0.256	-0.0395	-0.0923	0.2222	-0.1802	0.2762	0.1126	0.1366	0.6705	-0.18	0.1667	0.46	-0.332	0.9494	-10.5824	92.7291	-60.9698
107	0.0252	-0.0304	0.0151	0.0439	-0.0314	0.0169	-0.1053	-0.0722	0.007	-0.2337	-0.5157	0.0384	-0.1795	-0.0508	0	1.2294	-0.2287	0.3167	0.6298	-0.1548	1.1477	-1.0702	94.5243	-62.5217
108	0.0273	-0.0207	0.0522	0.0139	-0.0439	0.1025	-0.1203	0.0638	0.0549	0.0343	-0.1102	0.1624	-0.0531	0.1538	-0.0083	1.2104	-0.1287	-0.0672	0.5297	-0.2603	1.2075	-2.9238	102.9719	-65.4543
109	0.0133	-0.022	0.0143	0.1368	0.0535	0.0237	0.0242	-0.2002	0.2086	0.1762	-0.0775	-0.0845	0.1451	0.0709	0.0259	0.4183	-0.235	-0.0269	0.4439	0.1149	0.7602	-21.8617	68.8425	-53.5444
110	0.0415	0.049	-0.0542	0.028	-0.0462	0.0735	0.0721	0.0093	-0.0133	-0.0525	-0.173	0.0588	0.1408	-0.0319	-0.0218	0.3981	0.0021	0.2602	0.2502	-0.0326	0.6873	-22.5191	71.9562	-66.5947
111	0.0237	0.007	0.0469	0.0082	0.0011	0.0671	-0.0599	0.0414	0.0563	-0.0285	-0.2569	-0.1056	0.1846	-0.0713	-0.109	0.5358	-0.263	0.1686	0.5085	0.0912	0.9047	-23.0156	69.9913	-57.8187
112	0.0004	0.006	0.0006	0.0096	-0.0092	0.0033	0.0011	-0.02	-0.0524	0.0019	0.0423	0.0146	0.1311	0.0293	0	0.7395	-0.1205	-0.1413	0.3803	-0.039	1.0677	-0.7441	72.5922	-56.1793
113	0.0227	0.0013	0.0221	0.0024	-0.0019	0.006	-0.0569	0.0012	-0.0561	0.0823	-0.041	-0.0034	-0.2699	0.1009	0	0.924	-0.1041	-0.2748	0.6428	-0.0416	1.7122	7.5623	96.8976	-54.843
114	0.0602	-0.0377	-0.0161	0.0402	-0.0181	0.017	-0.3295	0.1551	-0.1225	0.2156	-0.0905	-0.146	-0.0395	0.0774	0	1.0209	-0.1881	0.1937	0.749	-0.2247	0.8991	4.206	86.2353	-48.5859
115	0.0134	0.0004	0.0048	0.0033	0.0109	-0.0029	0.1369	-0.1418	-0.0887	0.0972	0.0932	0.0593	-0.2307	0.0647	0.0001	0.752	-0.2146	0.0361	1.2539	-0.032	0.821	7.0562	99.4571	-47.4659
116	0.0252	-0.017	0.0158	0.0094	-0.009	0.0088	0.0965	0.0099	-0.1115	-0.015	0.0523	-0.003	0.138	0.0162	0	1.1394	0.0914	-0.1676	1.1781	-0.07	1.7414	16.0073	90.8894	-48.8549
117	0.3219	0.0419	-0.0761	0.072	0.0112	0.0186	0.165	-0.3722	0.3691	-0.2632	0.0456	-0.0929	-0.2613	0.0876	0.244	0.5719	0.1116	-0.0371	-0.3983	-0.4014	0.2039	-72.6274	90.5756	-32.044
118	0.0233	0.0051	0.0335	-0.0071	-0.0081	0.0117	-0.0728	0.0239	0.0101	0.2402	0.0426	-0.0728	-0.2822	-0.1054	0	1.8228	-0.7203	0.5394	1.7828	-0.8157	2.3654	-57.2868	118.3921	-13.1941
119	0.1555	0.0909	0.0105	0.027	0.0129	0.1989	0.102	-0.0285	0.0482	0.0102	-0.017	0.1134	0.0604	0.3021	0.0067	0.1458	-0.5604	-0.0279	-0.4683	-0.2626	0.3443	-50.4324	92.0435	-38.4555
120	0.0881	0.0154	0.0033	0.0285	-0.0208	0.0897	-0.2535	0.1224	0.2189	0.1564	0.183	0.0474	-0.0076	0.3665	-0.0207	2.0554	-0.7108	0.2996	1.62	-0.6909	1.529	-46.2997	109.8875	-6.3939
121	0.0497	0.0209	0.0405	0.0128	0.0133	0.047	0.0163	-0.0377	0.0206	0.056	-0.0048	-0.0383	0.0443	-0.1817	0.0876	0.5184	0.1114	0.3286	0.4908	0.0388	0.4907	-88.5392	40.7379	-14.8012
122	0.0717	0.0502	0.0451	0.3116	-0.1569	0.1316	0.0718	-0.1585	-0.1243	-0.0326	0.1046	-0.1255	-0.1158	0.1713	0.036	0.1287	0.0614	0.1056	0.3125	-0.04	0.2489	-82.3617	45.2292	-26.2756
123	0.1662	-0.2318	-0.0371	0.3073	-0.1566	0.0907	0.1092	-0.2106	0.0563	-0.0588	0.0579	-0.326	-0.273	-0.3894	0.0248	0.3875	0.0016	0.0286	0.672	-0.0798	0.3133	-81.5348	46.7461	-8.1573
124	0.0478	-0.0098	0.0271	0.0212	-0.0328	0.0419	0.1187	-0.4329	-0.0535	-0.1659	0.2116	0.3329	-0.0259	-0.3065	0.0022	0.7588	-0.0921	0.0294	0.8261	-0.0155	0.3894	-85.9841	54.4717	13.8618
125	0.1456	-0.0505	0.0274	0.1515	0.0157	0.0141	-0.1135	-0.0295	0.2046	-0.021	-0.3351	0.0286	-0.0226	0.1626	-0.0358	0.6092	0.0883	0.0784	0.3853	-0.0927	0.3526	-69.8435	65.1253	-14.2126
126	0.0756	0.0879	-0.0365	0.1603	-0.208	0.4056	-0.0961	-0.1303	-0.077	0.0492	-0.2369	-0.0859	-0.0687	0.1717	-0.3806	0.3416	-0.1105	0.174	0.471	-0.1646	0.1571	-70.7018	63.198	-23.1873
127	-0.0062	0.0294	0.0053	0.021	-0.0171	0.0368	0.0077	-0.074	0.0866	0.142	-0.2876	0.3062	-0.1769	-0.0047	-0.5228	0.3827	0.0479	0.0319	0.1911	-0.1755	0.1226	-76.9277	65.1466	-19.0367
128	-0.0037	-0.0001	0.0093	0.0014	-0.012	0.0003	-0.04	-0.3009	-0.3554	0.0012	0.0597	0.0228	-0.0077	-0.0258	-0	1.0762	0.1352	0.0191	1.1125	0.0082	0.6281	-74.4994	54.589	18.64
129	0.0093	0.0031	0.0083	0.0098	0.0108	0.0095	-0.0461	-0.1824	-0.0661	-0.1138	-0.1086	-0.0163	-0.0949	-0.0312	-0	1.3849	-0.2498	0.014	1.1791	0.0285	0.6985	-64.8882	61.4278	8.9893
130	0.0113	0.0022	-0.0124	0.0136	0.0019	0.0116	0.0802	-0.1176	0.0108	0.0353	0.0159	-0.0454	0.0774	0.0827	0	0.8111	0.0339	0.0584	1.2241	-0.1758	0.6219	-70.4912	58.2866	8.1703
131	0.0874	0.0183	0.1261	-0.0026	0.0149	0.1827	-0.1787	-0.1296	0.1751	-0.018	-0.0294	-0.1855	-0.0081	0.2062	-0.2102	0.9645	-0.1497	-0.4374	1.0245	-0.0399	0.5349	-65.9998	56.1192	19.2297
132	0.0304	-0.0135	-0.005	0.0065	0.0002	0.0026	-0.059	-0.0775	0.2163	-0.0081	-0.0128	-0.1246	0.1173	-0.0216	0	0.5946	0.0629	0.1691	0.8941	-0.1953	0.7397	33.2109	-56.5726	-76.0554
133	0.0136	0.0422	-0.0044	0.1898	-0.0024	-0.0009	-0.0879	-0.1017	-0.0797	-0.2296	0.1787	-0.2123	-0.0185	0.0785	0.0071	0.3913	0.1436	-0.0341	0.9085	0.1346	0.4365	26.1137	-51.3735	-68.284
134	0.0777	-0.0624	-0.0283	0.0606	0.018	0.0068	0.113	0.0934	-0.0368	-0.0578	-0.1235	0.0051	-0.0463	-0.0479	-0.0205	0.5173	0.474	0.0817	0.5469	0.2598	0.3908	19.1925	-57.6628	-68.0416
135	0.0527	-0.0037	-0.0373	0.0274	0.0217	0.0285	0.1369	0.0092	0.0295	-0.1165	-0.0218	-0.0876	0.0575	0.1284	0.1026	0.3828	0.5605	0.2281	1.2075	0.0415	0.4563	27.2963	-57.3979	-73.0896
136	0.1115	0.0516	-0.1269	0.1264	0.0687	0.1758	0.0953	0.2636	0.0729	0.2381	0.0785	0.055	-0.1189	0.1796	-0.0808	0.4619	0.2291	0.6179	0.7271	0.0427	0.8561	27.9183	-50.6231	-75.808
137	0.0128	0.0111	0.0165	0.0075	-0.0025	0.0089	-0.3141	-0.0969	0.1868	-0.3395	-0.0445	0.0564	-0.1975	0.1587	-0	1.3865	0.2699	0.1516	1.237	0.4658	1.2983	38.3697	-40.4054	-105.2616
138	0.0045	0.0019	0.0026	0.0059	-0.0083	0.0116	-0.115	0.0545	-0.0391	0.022	-0.0928	0.0408	0.1324	0.0448	0	1.7171	-0.1543	0.0963	1.3803	0.4036	1.1876	29.7837	-46.64	-98.5992
139	0.0111	-0.0029	0.003	0.027	0.021	0.0138	-0.0235	0.2418	0.0931	0.3354	-0.0196	-0.0913	0.1683	0.0381	-0	1.4611	0.0366	0.5633	1.4318	0.438	1.1482	42.3575	-41.481	-105.1787
140	0.0462	-0.0306	0.0297	0.0436	0.0073	0.0189	-0.0875	-0.0642	0.0624	-0.2849	0.1428	0.2716	-0.0811	-0.0645	-0.0024	0.8344	0.044	0.2424	0.7294	0.1961	0.5434	12.1436	-35.2893	-77.1614
141	0.0716	0.0142	-0.0532	0.3082	-0.0588	0.0002	0.1633	0.6766	-0.4373	-1.0252	-0.0666	-0.2645	0.0147	0.3563	0.0961	0.7825	0.4427	0.0455	0.3873	0.5513	-0.5683	22.1988	-37.917	-95.7814
142	0.0021	-0.0159	-0.0037	0.0672	0.004	0.0127	-0.0667	-0.0484	0.1058	0.0798	0.0697	-0.139	0.0096	0.0142	0	0.7649	0.2326	0.0616	0.6066	0.1311	1.1879	-10.2577	-95.1373	-62.5791
143	0.0139	0.0048	-0.007	0.0296	-0.0013	0.0042	0.0569	-0.0098	-0.4226	-0.2248	-0.0954	0.1289	-0.1411	0.1109	-0	0.8317	0.2206	-0.0307	0.5638	0.0252	0.3545	-6.0215	-85.0095	-58.3789
144	0.094	-0.0292	-0.0049	0.0401	0.0118	0.0015	-0.1619	-0.1198	0.0003	0.0334	0.1031	-0.0182	0.0568	-0.0097	0.0289	0.6807	0.3093	-0.1444	0.2602	-0.1148	0.3074	-11.1499	-79.5611	-55.1976
145	0.0645	-0.0199	-0.0855	0.0423	0.0003	0.1325	-0.1144	-0.1042	-0.0017	0.1627	-0.0338	0.1854	0.0902	0.0676	-0.0126	1.0318	0.4437	0.0074	0.3596	0.0112	0.7274	-15.8504	-87.0225	-57.8418
146	0.0309	-0.0207	-0.0509	0.0223	0.0496	0.0726	0.3381	-0.0422	0.0854	-0.0549	0.4375	-0.159	-0.1029	0.0221	0.0091	0.9306	0.1993	-0.0036	0.7053	0.0317	0.8816	-7.4636	-88.1589	-65.6609
147	0.0047	-0.005	-0.0078	0.0149	-0.0017	0.0016	0.0623	0.0556	-0.059	-0.0751	0.2515	0.0718	-0.0626	-0.0016	-0	1.004	0.3282	0.0457	0.8785	0.1394	1.058	0.8537	-105.6261	-97.1809
148	0.0096	-0.0177	0.0068	-0.0037	-0.0094	0.0229	-0.0837	-0.0505	-0.1556	0.1037	-0.413	-0.0965	0.302	-0.0603	-0.0001	0.9751	0.175	0.0701	1.0799	-0.1718	0.9664	0.6767	-105.8932	-87.6146
149	0.006	0.0119	-0.0026	0.0294	-0.0185	0.0177	-0.1297	-0.0335	0.0073	-0.1741	-0.0501	-0.0041	0.0214	-0.1043	0.0017	0.3148	0.267	-0.0198	1.0741	0.1437	0.7297	1.7462	-72.253	-79.2799
150	0.2364	0.2261	0.0308	0.3029	0.0629	0.0203	0.0795	0.0757	0.1614	0.0069	0.0066	0.0723	0.0762	0.1408	-0.1235	0.0746	0.6673	0.2253	0.2177	-0.0387	0.1072	4.2615	-72.8512	-69.3532
151	0.0117	-0.0147	0.038	0.0104	-0.0089	0.0154	0.0504	0.0237	-0.1279	-0.043	0.213	0.0809	-0.1521	0.1262	0	1.2213	0.1409	-0.0831	1.0842	0.0544	0.8009	1.2552	-95.7364	-95.5638
152	0.0623	-0.0218	-0.021	0.0519	0.0522	0.0382	-0.1421	0.1365	0.1073	-0.4139	0.2295	0.248	0.1944	-0.1593	0.0054	1.3125	0.3006	-0.1458	1.2776	0.0022	0.5372	-3.9194	-94.0961	-101.1076
153	0.0234	-0.0005	-0.033	0.0314	-0.0381	0.0635	-0.0947	0.1279	0.1347	-0.1001	-0.1062	0.3653	-0.0967	0.0048	-0.0961	0.2947	-0.0101	-0.1236	0.2387	0.0193	0.7717	-48.7316	-62.1762	-42.8325
154	0.0105	0.0052	0.004	0.0021	0.033	0.0082	0.1569	-0.3424	-0.2307	0.0366	-0.0993	0.2172	0.0419	-0.1993	0.0727	0.3304	0.0481	-0.2792	0.516	-0.0862	1.1973	-51.4489	-61.9401	-46.0761
155	0.0102	-0.0022	-0.0024	0.0018	-0.0068	0.0141	0.0021	-0.0973	-0.0865	0.0163	-0.0987	0.0458	-0.0787	-0.0137	0	1.3265	-0.2923	0.1856	1.089	-0.5059	1.3004	-70.2177	-91.9836	-62.5515
156	0.0007	-0.0081	0.0022	0.0128	0.0177	0.0139	0.0649	-0.1905	0.1427	-0.0051	0.0298	-0.016	0.1197	0.0752	0	1.4346	-0.2239	-0.1152	1.1061	-0.1357	1.0081	-63.5621	-82.2958	-56.2508
157	0.0356	-0.0035	0.0225	0.0107	-0.0162	0.0269	-0.321	-0.0489	0.1245	-0.0488	-0.1093	0.0071	0.2954	-0.016	-0	1.2127	-0.0438	0.23	0.7804	-0.2013	1.364	-69.4346	-89.6635	-54.7512
158	0	0.0069	0.0137	0.0019	0.0211	0.0263	0.0137	0.3704	0.1728	-0.086	-0.1629	-0.0255	0.0403	0.0222	-0	0.674	0.1558	0.0383	0.4829	-0.0364	0.4947	-34.4706	-70.3198	-61.583
159	0.0142	-0.0124	-0.0018	-0.0023	-0.0095	0.0174	0.0071	0.0072	-0.1299	0.1082	-0.0251	0.2878	0.154	0.0014	-0.069	0.5557	0.3315	-0.1877	-0.0403	-0.2233	0.5581	-34.8212	-73.4175	-54.4507
160	0.0202	-0.0266	-0.0082	0.0446	-0.0281	0.063	0.1746	0.1576	0.0495	0.0557	0.24	-0.0279	0.0356	-0.2059	0.0001	1.2959	-0.1702	-0.0223	1.4121	-0.2053	1.0976	-61.4875	-86.3308	-70.2456
161	-0.0011	-0.0154	0.0189	0.1437	-0.1187	0.0892	-0.0826	0.2292	0.0431	-0.1203	-0.2137	-0.1517	0.0736	-0.1525	-0.0318	1.277	-0.1915	-0.4681	1.1182	-0.3375	0.9904	-70.4028	-88.9377	-75.6933
162	0.2016	0.0869	0.013	0.1321	-0.0867	0.2456	-0.4516	-0.1877	0.0628	0.1842	-0.0617	-0.0065	0.1037	-0.0783	-0.2153	0.3738	0.0946	0.1065	0.1818	-0.2519	0.8316	-44.6131	-6.9701	-46.0417
163	0.4723	-0.0701	-0.0328	0.0174	0.0064	0.0025	0.1432	0.2629	0.1601	0.1752	-0.2789	-0.0173	-0.1501	-0.1046	-0.1834	0.5863	0.1351	-0.1715	0.1344	-0.1178	0.1166	-39.0831	-16.9665	-43.208
164	0.1754	0.1462	-0.0978	0.1364	-0.0746	0.1424	-0.1032	-0.1448	-0.0082	-0.1241	-0.0403	-0.0031	0.0364	0.0931	-0.1867	0.3236	0.1246	-0.0388	0.1962	-0.0527	0.4234	-31.3441	-15.8862	-48.1638
165	0.0277	-0.0097	0.0008	-0.0012	-0.002	-0.0002	-0.0613	0.0175	-0.1228	0.0289	0.0058	0.0435	0.0306	-0.0184	-0.0554	0.4821	0.4647	-0.0104	0.4311	-0.183	0.3499	-35.9242	-7.3916	-43.7741
166	0.0198	-0.0155	-0.0095	0.0094	0.0041	0.0046	-0.2043	0.0685	-0.0438	0.0852	0.0439	0.1063	0.0501	0.0756	-0.0041	0.5315	0.0163	-0.257	0.5436	-0.0641	0.5553	-42.9127	-14.1741	-51.6955
167	-0.0013	-0.0036	0.0014	0.0114	-0.0121	0.0082	0.1161	-0.0984	-0.0598	0.056	-0.1916	-0.0485	0.0215	-0.0564	-0.0001	0.564	0.0481	-0.0649	0.3583	-0.0458	0.7908	-39.7164	-24.3045	-40.8567
168	0.1855	0.1855	-0.0043	0.1287	0.1081	0.3496	-0.1161	-0.0335	-0.2297	0.0103	-0.1604	0.792	0.2667	-0.1905	-0.128	0.5616	0.1277	-0.3508	0.3286	-0.1546	1.1271	-70.6967	-7.7711	-61.6039
169	0.0783	0.026	0.0273	0.121	0.1339	0.1382	0.0575	-0.001	-0.0584	-0.066	0.1773	0.0681	0.0005	0.0372	0.1519	0.7952	-0.014	-0.3504	0.4771	-0.0272	0.2525	-46.2343	-32.7569	-60.441
170	0.0174	0.0042	0.0233	0.0163	0.0092	0.0265	0.0113	0.0533	-0.0031	-0.0172	-0.1266	0.0356	-0.0395	0.0823	-0.0637	0.3592	-0.0501	-0.4804	0.3713	-0.008	0.854	-51.7778	-40.2445	-55.3801
171	0.0582	0.0231	0.0953	0.0246	0.0783	0.1336	-0.1975	-0.1107	-0.0454	0.0034	-0.0774	0.0714	-0.0455	-0.0174	-0.3034	-0.0721	0.5004	-0.2493	-0.446	0.1418	0.4782	-44.7146	-34.9301	-47.3839
172	0.1296	-0.0721	-0.2005	0.0673	0.1125	0.2836	0.0993	0.0181	-0.1432	-0.5217	-0.0807	0.2077	-0.3461	0.0661	0.011	0.6699	0.064	-0.5099	0.257	-0.2458	0.4156	-60.0657	-23.5506	-61.0289
173	0.028	-0.033	0.0876	0.0691	-0.0852	0.1968	-0.0912	0.4019	-0.0358	-0.1946	-0.2299	-0.0998	0.047	-0.0775	-0.0074	0.9425	0.0576	-0.3988	0.5474	-0.1772	0.7068	-65.8366	-21.4373	-72.1061
174	0.2539	-0.1286	-0.0623	0.1145	-0.0154	0.057	-0.0039	0.241	0.1632	0.0097	0.0137	-0.0023	0.068	-0.0026	0.0511	1.1117	-0.2393	-0.5283	0.6603	-0.03	1.0025	-68.0313	-9.2609	-77.7467
175	0.0459	0.0221	0.0134	0.0303	0.0363	0.0545	0.0092	0.1428	0.0624	0.0269	-0.0109	0.0132	0.142	-0.1496	-0.0316	1.3501	-0.1099	-0.9968	0.7879	-0.1562	0.931	-75.1908	-19.0982	-80.376
176	0.1024	0.0172	-0.0519	0.0758	-0.0418	0.0279	-0.1203	0.089	0.148	-0.1352	-0.0935	-0.3198	0.2891	0.172	-0.1898	0.2385	0.066	0.0837	0.255	0.1629	0.2341	8.8685	-10.6765	-63.0752
177	0.0975	-0.0682	0.0162	0.0468	-0.0056	0.0021	0.0765	-0.0023	0.1396	0.2592	-0.0263	-0.0528	0.0152	-0.017	0.0743	0.9369	-0.0812	0.2352	0.4291	0.0873	0.1964	3.4059	-6.2417	-67.2308
178	0.0188	-0.026	-0.0129	0.0281	0.0081	0.0121	-0.1411	-0.055	0.1304	0.0175	-0.1	0.0767	-0.1657	-0.0812	0	1.0623	-0.1037	0.0025	0.9653	0.169	1.3839	-8.5135	16.0947	-88.2546
179	0.0017	-0.0008	-0.0199	0.0133	0.0358	0.0795	0.0936	-0.0268	0.2137	-0.1286	0.0054	-0.0009	-0.159	0.5415	0.009	1.2773	0.2456	0.1677	0.7926	0.3353	1.283	-5.6119	15.8041	-87.3717
180	0.1409	-0.0563	-0.058	0.2819	-0.0659	0.0531	-0.1628	-0.2636	-0.1258	0.0965	-0.4483	0.0211	0.1562	-0.1088	-0.0324	0.7782	0.0848	0.0224	0.4255	-0.0812	0.3638	-18.6407	-10.9371	-69.7598
181	0.0587	-0.061	0.0496	0.0837	-0.0486	0.0863	0.0774	0.0843	-0.1322	-0.0918	-0.1418	0.0426	-0.1197	0.1033	-0.0809	0.5095	0.0426	-0.1772	0.1489	0.1842	0.4389	-15.464	-15.9314	-62.672
182	0.0212	0.0142	-0.0282	0.0505	-0.027	0.0773	-0.2747	-0.0503	0.1246	0.0809	-0.0766	-0.0749	-0.0285	0.0695	-0.0552	0.2983	0.0665	-0.0164	0.3555	0.0955	0.3911	-12.215	-6.2757	-55.726
183	1.0358	0.3246	-0.5054	0.5196	-0.1548	0.2434	-0.2974	-0.1701	-0.1464	-0.1645	-0.1718	-0.1117	-0.2316	0.1131	-0.1415	0.5757	-0.0171	-0.098	0.3117	-0.0111	0.2843	-18.2005	-9.3169	-61.3772
184	0.0479	-0.1281	-0.0511	0.3632	0.057	0.1378	-0.0287	-0.0379	-0.1896	0.0732	-0.1202	-0.0865	0.0023	-0.0415	-0.0368	0.7862	0.1175	-0.0593	0.1303	0.0086	0.44	-6.163	-18.6174	-64.1901
185	0.0821	0.0121	-0.0381	0.0389	0.0406	0.0742	0.0552	0.1327	0.0364	0.0043	0.0172	0.0016	0.0461	0.012	0.0338	0.5356	0.3615	0.0681	0.5159	-0.3564	0.3824	-25.1754	3.0831	-75.7129
186	0.0489	-0.0956	-0.0615	0.2426	0.1386	0.0807	-0.0139	0.1199	0.0838	-0.0405	-0.2035	-0.0053	0.0634	0.092	-0.0555	0.4567	-0.2501	-0.1668	1.3746	0.4048	0.6264	-11.3068	11.3652	-95.8947
187	0.0322	-0.0084	-0.0007	0.0369	-0.0328	0.0215	-0.1218	0.3224	-0.0124	0.2337	-0.0427	-0.0447	-0.0135	0.131	0	1.0347	0.089	-0.1187	0.9319	-0.1602	0.4542	-17.724	1.7876	-90.2893
188	0.0077	-0.0004	0.003	0.0138	-0.0029	0.0018	-0.0797	0.1385	-0.0604	0.2639	0.0847	-0.0651	0.0275	0.0616	0	0.4879	0.2864	-0.12	0.7912	0.1206	0.7867	-9.3226	5.2791	-100.3416
189	0.0234	0.0166	-0.0056	0.0185	-0.0009	-0.0002	-0.0072	0.1533	0.0673	-0.1896	-0.1576	-0.0592	-0.0047	-0.0418	-0.0264	0.8366	-0.0698	0.0141	1.1798	0.2941	0.5665	-21.5368	7.6057	-100.9169

Refinement TLS group

ID	Refine-ID	Refine TLS-ID	Selection details	Auth asym-ID	Auth seq-ID
1	X-RAY DIFFRACTION	1	chain 'A' and (resid 12 through 77 )	A	12 - 77
2	X-RAY DIFFRACTION	2	chain 'A' and (resid 78 through 115 )	A	78 - 115
3	X-RAY DIFFRACTION	3	chain 'A' and (resid 116 through 170 )	A	116 - 170
4	X-RAY DIFFRACTION	4	chain 'A' and (resid 171 through 295 )	A	171 - 295
5	X-RAY DIFFRACTION	5	chain 'A' and (resid 296 through 370 )	A	296 - 370
6	X-RAY DIFFRACTION	6	chain 'A' and (resid 371 through 427 )	A	371 - 427
7	X-RAY DIFFRACTION	7	chain 'A' and (resid 428 through 460 )	A	428 - 460
8	X-RAY DIFFRACTION	8	chain 'D' and (resid 12 through 77 )	D	12 - 77
9	X-RAY DIFFRACTION	9	chain 'D' and (resid 78 through 170 )	D	78 - 170
10	X-RAY DIFFRACTION	10	chain 'D' and (resid 171 through 324 )	D	171 - 324
11	X-RAY DIFFRACTION	11	chain 'D' and (resid 325 through 370 )	D	325 - 370
12	X-RAY DIFFRACTION	12	chain 'D' and (resid 371 through 427 )	D	371 - 427
13	X-RAY DIFFRACTION	13	chain 'D' and (resid 428 through 460 )	D	428 - 460
14	X-RAY DIFFRACTION	14	chain 'G' and (resid 12 through 115 )	G	12 - 115
15	X-RAY DIFFRACTION	15	chain 'G' and (resid 116 through 149 )	G	116 - 149
16	X-RAY DIFFRACTION	16	chain 'G' and (resid 150 through 198 )	G	150 - 198
17	X-RAY DIFFRACTION	17	chain 'G' and (resid 199 through 266 )	G	199 - 266
18	X-RAY DIFFRACTION	18	chain 'G' and (resid 267 through 313 )	G	267 - 313
19	X-RAY DIFFRACTION	19	chain 'G' and (resid 314 through 370 )	G	314 - 370
20	X-RAY DIFFRACTION	20	chain 'G' and (resid 371 through 427 )	G	371 - 427
21	X-RAY DIFFRACTION	21	chain 'G' and (resid 428 through 460 )	G	428 - 460
22	X-RAY DIFFRACTION	22	chain 'J' and (resid 12 through 77 )	J	12 - 77
23	X-RAY DIFFRACTION	23	chain 'J' and (resid 78 through 115 )	J	78 - 115
24	X-RAY DIFFRACTION	24	chain 'J' and (resid 116 through 149 )	J	116 - 149
25	X-RAY DIFFRACTION	25	chain 'J' and (resid 150 through 217 )	J	150 - 217
26	X-RAY DIFFRACTION	26	chain 'J' and (resid 218 through 370 )	J	218 - 370
27	X-RAY DIFFRACTION	27	chain 'J' and (resid 371 through 427 )	J	371 - 427
28	X-RAY DIFFRACTION	28	chain 'J' and (resid 428 through 460 )	J	428 - 460
29	X-RAY DIFFRACTION	29	chain 'M' and (resid 12 through 115 )	M	12 - 115
30	X-RAY DIFFRACTION	30	chain 'M' and (resid 116 through 149 )	M	116 - 149
31	X-RAY DIFFRACTION	31	chain 'M' and (resid 150 through 236 )	M	150 - 236
32	X-RAY DIFFRACTION	32	chain 'M' and (resid 237 through 298 )	M	237 - 298
33	X-RAY DIFFRACTION	33	chain 'M' and (resid 299 through 370 )	M	299 - 370
34	X-RAY DIFFRACTION	34	chain 'M' and (resid 371 through 427 )	M	371 - 427
35	X-RAY DIFFRACTION	35	chain 'M' and (resid 428 through 460 )	M	428 - 460
36	X-RAY DIFFRACTION	36	chain 'P' and (resid 12 through 115 )	P	12 - 115
37	X-RAY DIFFRACTION	37	chain 'P' and (resid 116 through 149 )	P	116 - 149
38	X-RAY DIFFRACTION	38	chain 'P' and (resid 150 through 170 )	P	150 - 170
39	X-RAY DIFFRACTION	39	chain 'P' and (resid 171 through 295 )	P	171 - 295
40	X-RAY DIFFRACTION	40	chain 'P' and (resid 296 through 370 )	P	296 - 370
41	X-RAY DIFFRACTION	41	chain 'P' and (resid 371 through 427 )	P	371 - 427
42	X-RAY DIFFRACTION	42	chain 'P' and (resid 428 through 460 )	P	428 - 460
43	X-RAY DIFFRACTION	43	chain 'S' and (resid 12 through 115 )	S	12 - 115
44	X-RAY DIFFRACTION	44	chain 'S' and (resid 116 through 170 )	S	116 - 170
45	X-RAY DIFFRACTION	45	chain 'S' and (resid 171 through 370 )	S	171 - 370
46	X-RAY DIFFRACTION	46	chain 'S' and (resid 371 through 427 )	S	371 - 427
47	X-RAY DIFFRACTION	47	chain 'S' and (resid 428 through 460 )	S	428 - 460
48	X-RAY DIFFRACTION	48	chain 'V' and (resid 12 through 77 )	V	12 - 77
49	X-RAY DIFFRACTION	49	chain 'V' and (resid 78 through 115 )	V	78 - 115
50	X-RAY DIFFRACTION	50	chain 'V' and (resid 116 through 170 )	V	116 - 170
51	X-RAY DIFFRACTION	51	chain 'V' and (resid 171 through 217 )	V	171 - 217
52	X-RAY DIFFRACTION	52	chain 'V' and (resid 218 through 279 )	V	218 - 279
53	X-RAY DIFFRACTION	53	chain 'V' and (resid 280 through 324 )	V	280 - 324
54	X-RAY DIFFRACTION	54	chain 'V' and (resid 325 through 370 )	V	325 - 370
55	X-RAY DIFFRACTION	55	chain 'V' and (resid 371 through 427 )	V	371 - 427
56	X-RAY DIFFRACTION	56	chain 'V' and (resid 428 through 460 )	V	428 - 460
57	X-RAY DIFFRACTION	57	chain 'Y' and (resid 12 through 115 )	Y	12 - 115
58	X-RAY DIFFRACTION	58	chain 'Y' and (resid 116 through 149 )	Y	116 - 149
59	X-RAY DIFFRACTION	59	chain 'Y' and (resid 150 through 170 )	Y	150 - 170
60	X-RAY DIFFRACTION	60	chain 'Y' and (resid 171 through 370 )	Y	171 - 370
61	X-RAY DIFFRACTION	61	chain 'Y' and (resid 371 through 427 )	Y	371 - 427
62	X-RAY DIFFRACTION	62	chain 'Y' and (resid 428 through 460 )	Y	428 - 460
63	X-RAY DIFFRACTION	63	chain 'b' and (resid 12 through 77 )	b	12 - 77
64	X-RAY DIFFRACTION	64	chain 'b' and (resid 78 through 115 )	b	78 - 115
65	X-RAY DIFFRACTION	65	chain 'b' and (resid 116 through 149 )	b	116 - 149
66	X-RAY DIFFRACTION	66	chain 'b' and (resid 150 through 170 )	b	150 - 170
67	X-RAY DIFFRACTION	67	chain 'b' and (resid 171 through 251 )	b	171 - 251
68	X-RAY DIFFRACTION	68	chain 'b' and (resid 252 through 279 )	b	252 - 279
69	X-RAY DIFFRACTION	69	chain 'b' and (resid 280 through 324 )	b	280 - 324
70	X-RAY DIFFRACTION	70	chain 'b' and (resid 325 through 370 )	b	325 - 370
71	X-RAY DIFFRACTION	71	chain 'b' and (resid 371 through 427 )	b	371 - 427
72	X-RAY DIFFRACTION	72	chain 'b' and (resid 428 through 460 )	b	428 - 460
73	X-RAY DIFFRACTION	73	chain 'B' and (resid 1 through 20 )	B	1 - 20
74	X-RAY DIFFRACTION	74	chain 'B' and (resid 21 through 43 )	B	21 - 43
75	X-RAY DIFFRACTION	75	chain 'B' and (resid 44 through 87 )	B	44 - 87
76	X-RAY DIFFRACTION	76	chain 'B' and (resid 88 through 99 )	B	88 - 99
77	X-RAY DIFFRACTION	77	chain 'B' and (resid 100 through 152 )	B	100 - 152
78	X-RAY DIFFRACTION	78	chain 'B' and (resid 153 through 169 )	B	153 - 169
79	X-RAY DIFFRACTION	79	chain 'B' and (resid 170 through 180 )	B	170 - 180
80	X-RAY DIFFRACTION	80	chain 'B' and (resid 181 through 218 )	B	181 - 218
81	X-RAY DIFFRACTION	81	chain 'C' and (resid 1 through 17 )	C	1 - 17
82	X-RAY DIFFRACTION	82	chain 'C' and (resid 18 through 38 )	C	18 - 38
83	X-RAY DIFFRACTION	83	chain 'C' and (resid 39 through 61 )	C	39 - 61
84	X-RAY DIFFRACTION	84	chain 'C' and (resid 62 through 90 )	C	62 - 90
85	X-RAY DIFFRACTION	85	chain 'C' and (resid 91 through 139 )	C	91 - 139
86	X-RAY DIFFRACTION	86	chain 'C' and (resid 140 through 172 )	C	140 - 172
87	X-RAY DIFFRACTION	87	chain 'C' and (resid 173 through 188 )	C	173 - 188
88	X-RAY DIFFRACTION	88	chain 'C' and (resid 189 through 214 )	C	189 - 214
89	X-RAY DIFFRACTION	89	chain 'E' and (resid 1 through 20 )	E	1 - 20
90	X-RAY DIFFRACTION	90	chain 'E' and (resid 21 through 43 )	E	21 - 43
91	X-RAY DIFFRACTION	91	chain 'E' and (resid 44 through 71 )	E	44 - 71
92	X-RAY DIFFRACTION	92	chain 'E' and (resid 72 through 152 )	E	72 - 152
93	X-RAY DIFFRACTION	93	chain 'E' and (resid 153 through 218 )	E	153 - 218
94	X-RAY DIFFRACTION	94	chain 'F' and (resid 1 through 76 )	F	1 - 76
95	X-RAY DIFFRACTION	95	chain 'F' and (resid 77 through 102 )	F	77 - 102
96	X-RAY DIFFRACTION	96	chain 'F' and (resid 103 through 113 )	F	103 - 113
97	X-RAY DIFFRACTION	97	chain 'F' and (resid 114 through 150 )	F	114 - 150
98	X-RAY DIFFRACTION	98	chain 'F' and (resid 151 through 172 )	F	151 - 172
99	X-RAY DIFFRACTION	99	chain 'F' and (resid 173 through 188 )	F	173 - 188
100	X-RAY DIFFRACTION	100	chain 'F' and (resid 189 through 214 )	F	189 - 214
101	X-RAY DIFFRACTION	101	chain 'H' and (resid 1 through 20 )	H	1 - 20
102	X-RAY DIFFRACTION	102	chain 'H' and (resid 21 through 43 )	H	21 - 43
103	X-RAY DIFFRACTION	103	chain 'H' and (resid 44 through 71 )	H	44 - 71
104	X-RAY DIFFRACTION	104	chain 'H' and (resid 72 through 87 )	H	72 - 87
105	X-RAY DIFFRACTION	105	chain 'H' and (resid 88 through 99 )	H	88 - 99
106	X-RAY DIFFRACTION	106	chain 'H' and (resid 100 through 152 )	H	100 - 152
107	X-RAY DIFFRACTION	107	chain 'H' and (resid 153 through 200 )	H	153 - 200
108	X-RAY DIFFRACTION	108	chain 'H' and (resid 201 through 218 )	H	201 - 218
109	X-RAY DIFFRACTION	109	chain 'I' and (resid 1 through 38 )	I	1 - 38
110	X-RAY DIFFRACTION	110	chain 'I' and (resid 39 through 61 )	I	39 - 61
111	X-RAY DIFFRACTION	111	chain 'I' and (resid 62 through 102 )	I	62 - 102
112	X-RAY DIFFRACTION	112	chain 'I' and (resid 103 through 113 )	I	103 - 113
113	X-RAY DIFFRACTION	113	chain 'I' and (resid 114 through 139 )	I	114 - 139
114	X-RAY DIFFRACTION	114	chain 'I' and (resid 140 through 172 )	I	140 - 172
115	X-RAY DIFFRACTION	115	chain 'I' and (resid 173 through 188 )	I	173 - 188
116	X-RAY DIFFRACTION	116	chain 'I' and (resid 189 through 214 )	I	189 - 214
117	X-RAY DIFFRACTION	117	chain 'K' and (resid 1 through 126 )	K	1 - 126
118	X-RAY DIFFRACTION	118	chain 'K' and (resid 127 through 218 )	K	127 - 218
119	X-RAY DIFFRACTION	119	chain 'L' and (resid 1 through 113 )	L	1 - 113
120	X-RAY DIFFRACTION	120	chain 'L' and (resid 114 through 214 )	L	114 - 214
121	X-RAY DIFFRACTION	121	chain 'N' and (resid 1 through 20 )	N	1 - 20
122	X-RAY DIFFRACTION	122	chain 'N' and (resid 21 through 60 )	N	21 - 60
123	X-RAY DIFFRACTION	123	chain 'N' and (resid 61 through 152 )	N	61 - 152
124	X-RAY DIFFRACTION	124	chain 'N' and (resid 153 through 218 )	N	153 - 218
125	X-RAY DIFFRACTION	125	chain 'O' and (resid 1 through 17 )	O	1 - 17
126	X-RAY DIFFRACTION	126	chain 'O' and (resid 18 through 38 )	O	18 - 38
127	X-RAY DIFFRACTION	127	chain 'O' and (resid 39 through 113 )	O	39 - 113
128	X-RAY DIFFRACTION	128	chain 'O' and (resid 114 through 139 )	O	114 - 139
129	X-RAY DIFFRACTION	129	chain 'O' and (resid 140 through 150 )	O	140 - 150
130	X-RAY DIFFRACTION	130	chain 'O' and (resid 151 through 172 )	O	151 - 172
131	X-RAY DIFFRACTION	131	chain 'O' and (resid 173 through 214 )	O	173 - 214
132	X-RAY DIFFRACTION	132	chain 'g' and (resid 1 through 20 )	g	1 - 20
133	X-RAY DIFFRACTION	133	chain 'g' and (resid 21 through 43 )	g	21 - 43
134	X-RAY DIFFRACTION	134	chain 'g' and (resid 44 through 71 )	g	44 - 71
135	X-RAY DIFFRACTION	135	chain 'g' and (resid 72 through 99 )	g	72 - 99
136	X-RAY DIFFRACTION	136	chain 'g' and (resid 100 through 126 )	g	100 - 126
137	X-RAY DIFFRACTION	137	chain 'g' and (resid 127 through 169 )	g	127 - 169
138	X-RAY DIFFRACTION	138	chain 'g' and (resid 170 through 180 )	g	170 - 180
139	X-RAY DIFFRACTION	139	chain 'g' and (resid 181 through 218 )	g	181 - 218
140	X-RAY DIFFRACTION	140	chain 'j' and (resid 1 through 38 )	j	1 - 38
141	X-RAY DIFFRACTION	141	chain 'j' and (resid 39 through 214 )	j	39 - 214
142	X-RAY DIFFRACTION	142	chain 'Q' and (resid 1 through 20 )	Q	1 - 20
143	X-RAY DIFFRACTION	143	chain 'Q' and (resid 21 through 43 )	Q	21 - 43
144	X-RAY DIFFRACTION	144	chain 'Q' and (resid 44 through 60 )	Q	44 - 60
145	X-RAY DIFFRACTION	145	chain 'Q' and (resid 61 through 87 )	Q	61 - 87
146	X-RAY DIFFRACTION	146	chain 'Q' and (resid 88 through 126 )	Q	88 - 126
147	X-RAY DIFFRACTION	147	chain 'Q' and (resid 127 through 152 )	Q	127 - 152
148	X-RAY DIFFRACTION	148	chain 'Q' and (resid 153 through 218 )	Q	153 - 218
149	X-RAY DIFFRACTION	149	chain 'R' and (resid 1 through 17 )	R	1 - 17
150	X-RAY DIFFRACTION	150	chain 'R' and (resid 18 through 102 )	R	18 - 102
151	X-RAY DIFFRACTION	151	chain 'R' and (resid 103 through 128 )	R	103 - 128
152	X-RAY DIFFRACTION	152	chain 'R' and (resid 129 through 214 )	R	129 - 214
153	X-RAY DIFFRACTION	153	chain 'T' and (resid 1 through 60 )	T	1 - 60
154	X-RAY DIFFRACTION	154	chain 'T' and (resid 61 through 126 )	T	61 - 126
155	X-RAY DIFFRACTION	155	chain 'T' and (resid 127 through 152 )	T	127 - 152
156	X-RAY DIFFRACTION	156	chain 'T' and (resid 153 through 180 )	T	153 - 180
157	X-RAY DIFFRACTION	157	chain 'T' and (resid 181 through 218 )	T	181 - 218
158	X-RAY DIFFRACTION	158	chain 'U' and (resid 1 through 38 )	U	1 - 38
159	X-RAY DIFFRACTION	159	chain 'U' and (resid 39 through 102 )	U	39 - 102
160	X-RAY DIFFRACTION	160	chain 'U' and (resid 103 through 172 )	U	103 - 172
161	X-RAY DIFFRACTION	161	chain 'U' and (resid 173 through 214 )	U	173 - 214
162	X-RAY DIFFRACTION	162	chain 'W' and (resid 1 through 20 )	W	1 - 20
163	X-RAY DIFFRACTION	163	chain 'W' and (resid 21 through 43 )	W	21 - 43
164	X-RAY DIFFRACTION	164	chain 'W' and (resid 44 through 71 )	W	44 - 71
165	X-RAY DIFFRACTION	165	chain 'W' and (resid 72 through 87 )	W	72 - 87
166	X-RAY DIFFRACTION	166	chain 'W' and (resid 88 through 99 )	W	88 - 99
167	X-RAY DIFFRACTION	167	chain 'W' and (resid 100 through 113 )	W	100 - 113
168	X-RAY DIFFRACTION	168	chain 'W' and (resid 114 through 218 )	W	114 - 218
169	X-RAY DIFFRACTION	169	chain 'X' and (resid 1 through 13 )	X	1 - 13
170	X-RAY DIFFRACTION	170	chain 'X' and (resid 14 through 25 )	X	14 - 25
171	X-RAY DIFFRACTION	171	chain 'X' and (resid 26 through 75 )	X	26 - 75
172	X-RAY DIFFRACTION	172	chain 'X' and (resid 76 through 139 )	X	76 - 139
173	X-RAY DIFFRACTION	173	chain 'X' and (resid 140 through 172 )	X	140 - 172
174	X-RAY DIFFRACTION	174	chain 'X' and (resid 173 through 188 )	X	173 - 188
175	X-RAY DIFFRACTION	175	chain 'X' and (resid 189 through 214 )	X	189 - 214
176	X-RAY DIFFRACTION	176	chain 'Z' and (resid 1 through 87 )	Z	1 - 87
177	X-RAY DIFFRACTION	177	chain 'Z' and (resid 88 through 126 )	Z	88 - 126
178	X-RAY DIFFRACTION	178	chain 'Z' and (resid 127 through 169 )	Z	127 - 169
179	X-RAY DIFFRACTION	179	chain 'Z' and (resid 170 through 218 )	Z	170 - 218
180	X-RAY DIFFRACTION	180	chain 'a' and (resid 1 through 17 )	a	1 - 17
181	X-RAY DIFFRACTION	181	chain 'a' and (resid 18 through 38 )	a	18 - 38
182	X-RAY DIFFRACTION	182	chain 'a' and (resid 39 through 61 )	a	39 - 61
183	X-RAY DIFFRACTION	183	chain 'a' and (resid 62 through 90 )	a	62 - 90
184	X-RAY DIFFRACTION	184	chain 'a' and (resid 91 through 102 )	a	91 - 102
185	X-RAY DIFFRACTION	185	chain 'a' and (resid 103 through 113 )	a	103 - 113
186	X-RAY DIFFRACTION	186	chain 'a' and (resid 114 through 139 )	a	114 - 139
187	X-RAY DIFFRACTION	187	chain 'a' and (resid 140 through 172 )	a	140 - 172
188	X-RAY DIFFRACTION	188	chain 'a' and (resid 173 through 188 )	a	173 - 188
189	X-RAY DIFFRACTION	189	chain 'a' and (resid 189 through 214 )	a	189 - 214

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