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TitleRational design of a cross-type HPV vaccine through immunodominance shift guided by a cross-neutralizing antibody.
Journal, issue, pagesSci Bull (Beijing), Vol. 69, Page 512-525, Year 2024
Publish dateMay 24, 2021 (structure data deposition date)
AuthorsWang, Z. / Wang, D. / Chen, J. / Gao, F. / Jiang, Y. / Yang, C. / Qian, C. / Chi, X. / Zhang, S. / Xu, Y. ...Wang, Z. / Wang, D. / Chen, J. / Gao, F. / Jiang, Y. / Yang, C. / Qian, C. / Chi, X. / Zhang, S. / Xu, Y. / Lu, Y. / Shen, J. / Zhang, C. / Li, J. / Zhou, L. / Li, T. / Zheng, Q. / Yu, H. / Li, S. / Xia, N. / Gu, Y.
External linksSci Bull (Beijing) / PubMed:38160175
MethodsX-ray diffraction
Resolution3.366 - 3.606 Å
Structure data

PDB-7ew5:
immune complex of HPV6 L1 pentamer and neutralizing antibody 13H5
Method: X-RAY DIFFRACTION / Resolution: 3.606 Å

PDB-7f8i:
Crystal structure of HPV6 L1 pentamer
Method: X-RAY DIFFRACTION / Resolution: 3.366 Å

Source
  • human papillomavirus type 6
  • mus musculus (house mouse)
KeywordsVIRAL PROTEIN / immune complex

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