Entry Database : PDB / ID : 7eif Structure visualization Downloads & linksTitle Crystal structure of GAS41 YEATS domain ComponentsYEATS domain-containing protein 4 Details Keywords NUCLEAR PROTEIN / YEATS domain / Transcription / Complex / Histone modificationFunction / homology Function and homology informationFunction Domain/homology Component
modification-dependent protein binding / regulation of double-strand break repair / Activation of the TFAP2 (AP-2) family of transcription factors / NuA4 histone acetyltransferase complex / positive regulation of double-strand break repair via homologous recombination / lysine-acetylated histone binding / structural constituent of cytoskeleton / nuclear matrix / nucleosome / mitotic cell cycle ... modification-dependent protein binding / regulation of double-strand break repair / Activation of the TFAP2 (AP-2) family of transcription factors / NuA4 histone acetyltransferase complex / positive regulation of double-strand break repair via homologous recombination / lysine-acetylated histone binding / structural constituent of cytoskeleton / nuclear matrix / nucleosome / mitotic cell cycle / HATs acetylate histones / histone binding / regulation of apoptotic process / nuclear membrane / regulation of cell cycle / chromatin remodeling / regulation of DNA-templated transcription / regulation of transcription by RNA polymerase II / positive regulation of DNA-templated transcription / nucleoplasm / nucleus Similarity search - FunctionBiological species Homo sapiens (human)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 1.58 Å DetailsAuthors Kikuchi, M. / Umehara, T. Funding support Japan, 1items Details Hide detailsOrganization Grant number Country Japan Society for the Promotion of Science (JSPS) Japan
CitationJournal : Proc.Natl.Acad.Sci.USA / Year : 2023Title : GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain.Authors : Kikuchi, M. / Takase, S. / Konuma, T. / Noritsugu, K. / Sekine, S. / Ikegami, T. / Ito, A. / Umehara, T. History Deposition Mar 30, 2021 Deposition site : PDBJ / Processing site : PDBJRevision 1.0 Apr 6, 2022 Provider : repository / Type : Initial releaseRevision 1.1 Nov 1, 2023 Group : Data collection / Database referencesCategory : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / citation / citation_author Item : _citation.country / _citation.journal_abbrev ... _citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year / _citation_author.identifier_ORCID / _citation_author.name Revision 1.2 Nov 29, 2023 Group : Refinement description / Category : pdbx_initial_refinement_model
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