Entry | Database: PDB / ID: 7ei0 |
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Title | Crystal structure of falcipain 2 from 3D7 strain |
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Components | Cysteine proteinase falcipain 2a |
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Keywords | HYDROLASE / malaria / plasmodium / protease / falcipain 2 / drug target |
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Function / homology | Function and homology information
MHC class II antigen presentation / Neutrophil degranulation / food vacuole / proteolysis involved in protein catabolic process / Hydrolases; Acting on peptide bonds (peptidases); Cysteine endopeptidases / cysteine-type endopeptidase activity / proteolysis / extracellular space / membraneSimilarity search - Function Cathepsin propeptide inhibitor domain (I29) / Cathepsin propeptide inhibitor domain (I29) / Cathepsin propeptide inhibitor domain (I29) / Papain-like cysteine endopeptidase / : / Cysteine peptidase, histidine active site / Eukaryotic thiol (cysteine) proteases histidine active site. / Peptidase C1A, papain C-terminal / Papain family cysteine protease / Papain family cysteine protease ...Cathepsin propeptide inhibitor domain (I29) / Cathepsin propeptide inhibitor domain (I29) / Cathepsin propeptide inhibitor domain (I29) / Papain-like cysteine endopeptidase / : / Cysteine peptidase, histidine active site / Eukaryotic thiol (cysteine) proteases histidine active site. / Peptidase C1A, papain C-terminal / Papain family cysteine protease / Papain family cysteine protease / Cysteine peptidase, cysteine active site / Eukaryotic thiol (cysteine) proteases cysteine active site. / Papain-like cysteine peptidase superfamilySimilarity search - Domain/homology |
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Biological species | ![](img/tx_eukaryote.gif) Plasmodium falciparum (malaria parasite P. falciparum) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3.4 Å |
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Authors | Chakraborty, S. / Biswas, S. |
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Citation | Journal: Biochem.Biophys.Res.Commun. / Year: 2022 Title: New insights of falcipain 2 structure from Plasmodium falciparum 3D7 strain. Authors: Chakraborty, S. / Alam, B. / Biswas, S. |
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History | Deposition | Mar 30, 2021 | Deposition site: PDBJ / Processing site: PDBJ |
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Revision 1.0 | Apr 6, 2022 | Provider: repository / Type: Initial release |
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Revision 1.1 | Oct 19, 2022 | Group: Database references / Category: citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year |
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Revision 1.2 | Nov 29, 2023 | Group: Data collection / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model / struct_ncs_dom_lim Item: _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id ..._struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id |
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