+Open data
-Basic information
Entry | Database: PDB / ID: 7csr | ||||||
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Title | Structure of Ephexin4 R676L | ||||||
Components | Rho guanine nucleotide exchange factor 16 | ||||||
Keywords | SIGNALING PROTEIN / Ephexin4 / GEF / Autoinhibition | ||||||
Function / homology | Function and homology information CDC42 GTPase cycle / NRAGE signals death through JNK / RHOG GTPase cycle / G alpha (12/13) signalling events / activation of GTPase activity / cell chemotaxis / guanyl-nucleotide exchange factor activity / PDZ domain binding / positive regulation of protein localization to plasma membrane / receptor tyrosine kinase binding ...CDC42 GTPase cycle / NRAGE signals death through JNK / RHOG GTPase cycle / G alpha (12/13) signalling events / activation of GTPase activity / cell chemotaxis / guanyl-nucleotide exchange factor activity / PDZ domain binding / positive regulation of protein localization to plasma membrane / receptor tyrosine kinase binding / small GTPase binding / cytoplasm Similarity search - Function | ||||||
Biological species | Mus musculus (house mouse) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3 Å | ||||||
Authors | Zhang, M. / Lin, L. / Wang, C. / Zhu, J. | ||||||
Citation | Journal: Proc.Natl.Acad.Sci.USA / Year: 2021 Title: Double inhibition and activation mechanisms of Ephexin family RhoGEFs. Authors: Zhang, M. / Lin, L. / Wang, C. / Zhu, J. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 7csr.cif.gz | 261.1 KB | Display | PDBx/mmCIF format |
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PDB format | pdb7csr.ent.gz | 209.9 KB | Display | PDB format |
PDBx/mmJSON format | 7csr.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/cs/7csr ftp://data.pdbj.org/pub/pdb/validation_reports/cs/7csr | HTTPS FTP |
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-Related structure data
Related structure data | 7csoSC 7cspC S: Starting model for refinement C: citing same article (ref.) |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: 1
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