- PDB-7cml: The Crystal Structure of human JNK2 from Biortus. -
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Basic information
Entry
Database: PDB / ID: 7cml
Title
The Crystal Structure of human JNK2 from Biortus.
Components
Mitogen-activated protein kinase 9
Keywords
TRANSFERASE / Protein kinase-like / transcription factor binding
Function / homology
Function and homology information
protein localization to tricellular tight junction / JUN kinase activity / inflammatory response to wounding / positive regulation of macrophage derived foam cell differentiation / positive regulation of cytokine production involved in inflammatory response / positive regulation of podosome assembly / Activation of the AP-1 family of transcription factors / Fc-epsilon receptor signaling pathway / cellular response to cadmium ion / mitogen-activated protein kinase ...protein localization to tricellular tight junction / JUN kinase activity / inflammatory response to wounding / positive regulation of macrophage derived foam cell differentiation / positive regulation of cytokine production involved in inflammatory response / positive regulation of podosome assembly / Activation of the AP-1 family of transcription factors / Fc-epsilon receptor signaling pathway / cellular response to cadmium ion / mitogen-activated protein kinase / JNK cascade / protein serine/threonine/tyrosine kinase activity / JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 / positive regulation of apoptotic signaling pathway / positive regulation of protein ubiquitination / regulation of circadian rhythm / apoptotic signaling pathway / FCERI mediated MAPK activation / cellular response to reactive oxygen species / modulation of chemical synaptic transmission / Schaffer collateral - CA1 synapse / cellular senescence / rhythmic process / Signaling by ALK fusions and activated point mutants / positive regulation of proteasomal ubiquitin-dependent protein catabolic process / Oxidative Stress Induced Senescence / nuclear speck / protein phosphorylation / protein serine kinase activity / protein serine/threonine kinase activity / positive regulation of gene expression / mitochondrion / nucleoplasm / ATP binding / nucleus / plasma membrane / cytoplasm / cytosol Similarity search - Function
Mitogen-activated protein (MAP) kinase, JNK / : / Mitogen-activated protein (MAP) kinase, conserved site / MAP kinase signature. / Serine/threonine-protein kinase, active site / Serine/Threonine protein kinases active-site signature. / Serine/Threonine protein kinases, catalytic domain / Protein kinase domain / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily Similarity search - Domain/homology
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