- PDB-6y8e: 14-3-3 Sigma in complex with phosphorylated MLF1 peptide -
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基本情報
登録情報
データベース: PDB / ID: 6y8e
タイトル
14-3-3 Sigma in complex with phosphorylated MLF1 peptide
要素
14-3-3 protein sigma
ARG-SER-PHE-SEP-GLU-PRO-PHE-GLY
キーワード
PROTEIN BINDING / 14-3-3 / MLF1 / complex / protein / protein-protein interactions
機能・相同性
機能・相同性情報
regulation of cell cycle G1/S phase transition / myeloid progenitor cell differentiation / regulation of epidermal cell division / protein kinase C inhibitor activity / positive regulation of epidermal cell differentiation / keratinocyte development / keratinization / Regulation of localization of FOXO transcription factors / keratinocyte proliferation / phosphoserine residue binding ...regulation of cell cycle G1/S phase transition / myeloid progenitor cell differentiation / regulation of epidermal cell division / protein kinase C inhibitor activity / positive regulation of epidermal cell differentiation / keratinocyte development / keratinization / Regulation of localization of FOXO transcription factors / keratinocyte proliferation / phosphoserine residue binding / Activation of BAD and translocation to mitochondria / negative regulation of keratinocyte proliferation / establishment of skin barrier / SARS-CoV-2 targets host intracellular signalling and regulatory pathways / Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex / SARS-CoV-1 targets host intracellular signalling and regulatory pathways / negative regulation of stem cell proliferation / RHO GTPases activate PKNs / protein sequestering activity / protein kinase A signaling / negative regulation of innate immune response / protein export from nucleus / TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest / release of cytochrome c from mitochondria / ciliary basal body / positive regulation of protein export from nucleus / regulation of signal transduction by p53 class mediator / stem cell proliferation / Translocation of SLC2A4 (GLUT4) to the plasma membrane / TP53 Regulates Metabolic Genes / negative regulation of protein kinase activity / cilium / intrinsic apoptotic signaling pathway in response to DNA damage / protein localization / positive regulation of cell growth / regulation of cell cycle / cadherin binding / protein domain specific binding / DNA-templated transcription / regulation of DNA-templated transcription / protein kinase binding / perinuclear region of cytoplasm / negative regulation of transcription by RNA polymerase II / signal transduction / DNA binding / extracellular space / extracellular exosome / identical protein binding / nucleus / cytoplasm / cytosol 類似検索 - 分子機能
Myeloid leukemia factor / Myelodysplasia-myeloid leukemia factor 1-interacting protein / 14-3-3 protein sigma / 14-3-3 proteins signature 2. / 14-3-3 protein, conserved site / 14-3-3 proteins signature 1. / 14-3-3 protein / 14-3-3 homologues / 14-3-3 domain / 14-3-3 domain superfamily / 14-3-3 protein 類似検索 - ドメイン・相同性