+Open data
-Basic information
Entry | Database: PDB / ID: 6vwf | |||||||||
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Title | Structure of ALDH9A1 complexed with NAD+ in space group C222 | |||||||||
Components | 4-trimethylaminobutyraldehyde dehydrogenase | |||||||||
Keywords | OXIDOREDUCTASE / ALDEHYDE DEHYDROGENASE | |||||||||
Function / homology | Function and homology information formaldehyde dehydrogenase / 1-pyrroline dehydrogenase activity / 4-trimethylammoniobutyraldehyde dehydrogenase / 4-trimethylammoniobutyraldehyde dehydrogenase activity / formaldehyde dehydrogenase activity / Carnitine synthesis / carnitine biosynthetic process / aminobutyraldehyde dehydrogenase activity / aminobutyraldehyde dehydrogenase / cellular aldehyde metabolic process ...formaldehyde dehydrogenase / 1-pyrroline dehydrogenase activity / 4-trimethylammoniobutyraldehyde dehydrogenase / 4-trimethylammoniobutyraldehyde dehydrogenase activity / formaldehyde dehydrogenase activity / Carnitine synthesis / carnitine biosynthetic process / aminobutyraldehyde dehydrogenase activity / aminobutyraldehyde dehydrogenase / cellular aldehyde metabolic process / glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity / aldehyde dehydrogenase (NAD+) / aldehyde dehydrogenase (NAD+) activity / small molecule binding / protein homotetramerization / extracellular exosome / cytosol / cytoplasm Similarity search - Function | |||||||||
Biological species | Homo sapiens (human) | |||||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.64 Å | |||||||||
Authors | Wyatt, J.W. / Tanner, J.J. | |||||||||
Funding support | United States, 2items
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Citation | Journal: Arch.Biochem.Biophys. / Year: 2020 Title: Inhibition, crystal structures, and in-solution oligomeric structure of aldehyde dehydrogenase 9A1. Authors: Wyatt, J.W. / Korasick, D.A. / Qureshi, I.A. / Campbell, A.C. / Gates, K.S. / Tanner, J.J. | |||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 6vwf.cif.gz | 349.7 KB | Display | PDBx/mmCIF format |
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PDB format | pdb6vwf.ent.gz | 284.1 KB | Display | PDB format |
PDBx/mmJSON format | 6vwf.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/vw/6vwf ftp://data.pdbj.org/pub/pdb/validation_reports/vw/6vwf | HTTPS FTP |
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-Related structure data
Related structure data | 6vr6C 1a4sS S: Starting model for refinement C: citing same article (ref.) |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: 1
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