登録情報 | データベース: PDB / ID: 6uyh |
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タイトル | Crystal structure of prolyl-tRNA synthetase from Naegleria fowleri in complex with halofuginone and AMPPNP |
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要素 | Prolyl-tRNA synthetase |
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キーワード | LIGASE / SSGCID / Structural Genomics / halofuginone / AMPPNP / Seattle Structural Genomics Center for Infectious Disease |
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機能・相同性 | 機能・相同性情報
proline-tRNA ligase / proline-tRNA ligase activity / prolyl-tRNA aminoacylation / ATP binding / cytoplasm類似検索 - 分子機能 C-terminal domain of ProRS / Proline-tRNA ligase, class IIa / Proline-tRNA ligase, class II, C-terminal / Prolyl-tRNA synthetase, C-terminal / Prolyl-tRNA synthetase, C-terminal / Proline-tRNA ligase, class IIa, archaeal-type / Prolyl-tRNA synthetase, class II / Translation Initiation Factor IF3 / Anticodon-binding domain / Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) ...C-terminal domain of ProRS / Proline-tRNA ligase, class IIa / Proline-tRNA ligase, class II, C-terminal / Prolyl-tRNA synthetase, C-terminal / Prolyl-tRNA synthetase, C-terminal / Proline-tRNA ligase, class IIa, archaeal-type / Prolyl-tRNA synthetase, class II / Translation Initiation Factor IF3 / Anticodon-binding domain / Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) / tRNA synthetase class II core domain (G, H, P, S and T) / Anticodon-binding / Anticodon binding domain / Anticodon-binding domain superfamily / Bira Bifunctional Protein; Domain 2 / BirA Bifunctional Protein; domain 2 / Aminoacyl-tRNA synthetase, class II / Aminoacyl-transfer RNA synthetases class-II family profile. / Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) / Rossmann fold / 2-Layer Sandwich / 3-Layer(aba) Sandwich / Alpha Beta類似検索 - ドメイン・相同性 PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / Chem-HFG / Proline--tRNA ligase類似検索 - 構成要素 |
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生物種 | Naegleria fowleri (フォーラーネグレリア) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.75 Å |
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データ登録者 | Seattle Structural Genomics Center for Infectious Disease (SSGCID) |
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引用 | ジャーナル: TO BE PUBLISHED タイトル: Crystal structure of prolyl-tRNA synthetase from Naegleria fowleri in complex with halofuginone and AMPPNP 著者: Dranow, D.M. / Abendroth, J. / Lorimer, D.D. / Horanyi, P.S. / Edwards, T.E. |
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履歴 | 登録 | 2019年11月13日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2019年11月27日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2023年10月11日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_struct_conn_angle / struct_conn Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr2_auth_seq_id |
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