登録情報 | データベース: PDB / ID: 6sa5 |
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タイトル | SALSA / DMBT1 / GP340 SRCR domain 8 |
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要素 | Deleted in malignant brain tumors 1 protein |
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キーワード | IMMUNE SYSTEM / Scavenger receptor cysteine-rich / pattern recognition / mucosal immunology / anti-microbial molecule / complement / innate immunity / inflammation / salivary agglutinin / salivary scavenger and agglutinin |
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機能・相同性 | 機能・相同性情報
induction of bacterial agglutination / zymogen granule membrane / scavenger receptor activity / Surfactant metabolism / zymogen binding / pattern recognition receptor activity / epithelial cell differentiation / extracellular matrix / defense response / phagocytic vesicle membrane ...induction of bacterial agglutination / zymogen granule membrane / scavenger receptor activity / Surfactant metabolism / zymogen binding / pattern recognition receptor activity / epithelial cell differentiation / extracellular matrix / defense response / phagocytic vesicle membrane / calcium-dependent protein binding / protein transport / defense response to virus / defense response to Gram-negative bacterium / defense response to Gram-positive bacterium / innate immune response / extracellular space / extracellular exosome / extracellular region / cytoplasm類似検索 - 分子機能 : / Mac-2 Binding Protein / SRCR-like domain / SRCR domain signature. / Scavenger receptor cysteine-rich domain / Zona pellucida domain, conserved site / Zona pellucida, ZP-C domain / ZP domain signature. / Zona pellucida-like domain / Zona pellucida (ZP) domain ...: / Mac-2 Binding Protein / SRCR-like domain / SRCR domain signature. / Scavenger receptor cysteine-rich domain / Zona pellucida domain, conserved site / Zona pellucida, ZP-C domain / ZP domain signature. / Zona pellucida-like domain / Zona pellucida (ZP) domain / ZP domain profile. / Zona pellucida domain / SRCR domain / SRCR domain profile. / SRCR-like domain / SRCR-like domain superfamily / Scavenger receptor Cys-rich / CUB domain / Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein. / CUB domain / CUB domain profile. / Spermadhesin, CUB domain superfamily / Roll / Alpha Beta類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.29 Å |
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データ登録者 | Reichhardt, M.P. / Johnson, S. / Loimaranta, V. / Lea, S.M. |
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資金援助 | フィンランド, 英国, 2件 組織 | 認可番号 | 国 |
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Finnish Cultural Foundation | | フィンランド | Wellcome Trust | 100298 | 英国 |
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引用 | ジャーナル: Life Sci Alliance / 年: 2020 タイトル: Structures of SALSA/DMBT1 SRCR domains reveal the conserved ligand-binding mechanism of the ancient SRCR fold. 著者: Reichhardt, M.P. / Loimaranta, V. / Lea, S.M. / Johnson, S. |
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履歴 | 登録 | 2019年7月16日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2020年3月18日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2024年1月24日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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