Entry | Database: PDB / ID: 6ox6 |
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Title | Crystal structure of the complex between the Type VI effector Tas1 and its immunity protein |
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Components | |
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Keywords | TRANSFERASE / type VI secretion / bacterial warfare / (p)ppApp / alarmone / Pseudomonas aeruginosa / Structural Genomics / Center for Structural Genomics of Infectious Diseases / CSGID |
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Function / homology | Function and homology information
protein secretion by the type VI secretion system / NAD+ glycohydrolase / toxin sequestering activity / NADP+ nucleosidase activity / NAD+ nucleosidase activity / NAD+ nucleotidase, cyclic ADP-ribose generating / membrane => GO:0016020 / membraneSimilarity search - Function |
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Biological species | ![](img/tx_bacteria.gif) Pseudomonas aeruginosa (bacteria) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / SAD / Resolution: 2.17 Å |
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Authors | Ahmad, S. / Stogios, P.J. / Skarina, T. / Whitney, J. / Savchenko, A. / Satchell, K.J.F. / Joachimiak, A. / Center for Structural Genomics of Infectious Diseases (CSGID) |
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Funding support | United States, 2items Organization | Grant number | Country |
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National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) | HHSN272201200026C | United States | National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) | HHSN272201700060C | United States |
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Citation | Journal: Nature / Year: 2019 Title: An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp. Authors: Ahmad, S. / Wang, B. / Walker, M.D. / Tran, H.R. / Stogios, P.J. / Savchenko, A. / Grant, R.A. / McArthur, A.G. / Laub, M.T. / Whitney, J.C. |
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History | Deposition | May 13, 2019 | Deposition site: RCSB / Processing site: RCSB |
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Revision 1.0 | Sep 18, 2019 | Provider: repository / Type: Initial release |
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Revision 1.1 | Nov 6, 2019 | Group: Data collection / Database references / Category: citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.pdbx_database_id_DOI / _citation.title / _citation.year |
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Revision 1.2 | Nov 20, 2019 | Group: Database references / Category: citation / Item: _citation.pdbx_database_id_PubMed / _citation.title |
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Revision 1.3 | Dec 11, 2019 | Group: Database references / Category: citation Item: _citation.journal_volume / _citation.page_first / _citation.page_last |
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Revision 1.4 | Dec 18, 2019 | Group: Author supporting evidence / Category: pdbx_audit_support / Item: _pdbx_audit_support.funding_organization |
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