Entry Database : PDB / ID : 6k2g Structure visualization Downloads & linksTitle Structure of FraE in the monomer state ComponentsFraE Details Keywords TOXIN / actinoporin / pore forming protein / protein evolution / hemolysisFunction / homology Function and homology informationFunction Domain/homology Component
nematocyst / pore complex assembly / cytolysis in another organism / other organism cell membrane / channel activity / pore complex / monoatomic cation transport / toxin activity / lipid binding / extracellular region / identical protein binding Similarity search - Function Sea anemone actinoporin-like / Sea anemone cytotoxic protein / Cytolysin/lectin / Cytolysin/lectin / Mutm (Fpg) Protein; Chain: A, domain 2 / Sandwich / Mainly Beta Similarity search - Domain/homologyBiological species Actinia fragacea (sea anemone)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.22 Å DetailsAuthors Caaveiro, J.M.M. / Morante, K. / Tsumoto, K. Funding support Japan, 2items Details Hide detailsOrganization Grant number Country Japan Society for the Promotion of Science 15K06962 Japan Japan Society for the Promotion of Science 16H02420 Japan
CitationJournal : Toxins / Year : 2019Title : The Isolation of New Pore-Forming Toxins from the Sea AnemoneActinia fragaceaProvides Insights into the Mechanisms of Actinoporin Evolution.Authors : Morante, K. / Bellomio, A. / Viguera, A.R. / Gonzalez-Manas, J.M. / Tsumoto, K. / Caaveiro, J.M.M. History Deposition May 14, 2019 Deposition site : PDBJ / Processing site : PDBJRevision 1.0 Mar 25, 2020 Provider : repository / Type : Initial releaseRevision 1.1 Nov 22, 2023 Group : Data collection / Database references / Refinement descriptionCategory : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ncs_dom_lim Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id
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