登録情報 データベース : PDB / ID : 6jv7 構造の表示 ダウンロードとリンクタイトル Chimeric Rat C5a 要素Chimeric-rC5a D-anaphylatoxin C5a 詳細キーワード IMMUNE SYSTEM / C5aR / Immune / Chimeric機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
C5a anaphylatoxin chemotactic receptor binding / Terminal pathway of complement / Activation of C3 and C5 / Regulation of Complement cascade / Peptide ligand-binding receptors / negative regulation of norepinephrine secretion / membrane attack complex / negative regulation of dopamine secretion / inflammatory response to wounding / leukocyte migration involved in inflammatory response ... C5a anaphylatoxin chemotactic receptor binding / Terminal pathway of complement / Activation of C3 and C5 / Regulation of Complement cascade / Peptide ligand-binding receptors / negative regulation of norepinephrine secretion / membrane attack complex / negative regulation of dopamine secretion / inflammatory response to wounding / leukocyte migration involved in inflammatory response / positive regulation of chemotaxis / negative regulation of macrophage chemotaxis / glomerulus development / neutrophil homeostasis / complement activation, alternative pathway / G alpha (i) signalling events / endopeptidase inhibitor activity / positive regulation of vascular endothelial growth factor production / positive regulation of chemokine production / complement activation, classical pathway / kidney development / intracellular calcium ion homeostasis / positive regulation of angiogenesis / chemotaxis / positive regulation of cytosolic calcium ion concentration / in utero embryonic development / killing of cells of another organism / extracellular space 類似検索 - 分子機能 Anaphylotoxins (complement system) / Influenza Virus Matrix Protein; Chain A, domain 1 / : / Complement component 5, CUB domain / Complement C3/4/5, macroglobulin domain MG1 / Macroglobulin domain MG1 / Anaphylatoxin domain signature. / Anaphylatoxin, complement system / Anaphylatoxin/fibulin / Anaphylotoxin-like domain ... Anaphylotoxins (complement system) / Influenza Virus Matrix Protein; Chain A, domain 1 / : / Complement component 5, CUB domain / Complement C3/4/5, macroglobulin domain MG1 / Macroglobulin domain MG1 / Anaphylatoxin domain signature. / Anaphylatoxin, complement system / Anaphylatoxin/fibulin / Anaphylotoxin-like domain / Anaphylatoxin domain profile. / Anaphylatoxin homologous domain / : / Alpha-macroglobulin, receptor-binding / Alpha-macroglobulin, receptor-binding domain superfamily / Macroglobulin domain MG4 / Macroglobulin domain MG3 / A-macroglobulin receptor / Macroglobulin domain MG4 / Macroglobulin domain MG3 / A-macroglobulin receptor binding domain / Netrin C-terminal Domain / Netrin module, non-TIMP type / UNC-6/NTR/C345C module / Alpha-2-macroglobulin / Macroglobulin domain / Alpha-2-macroglobulin, bait region domain / Alpha-macroglobulin-like, TED domain / Alpha-2-Macroglobulin / Alpha-2-macroglobulin family / Alpha-2-macroglobulin family / A-macroglobulin TED domain / Alpha-2-macroglobulin bait region domain / MG2 domain / Netrin domain / NTR domain profile. / Tissue inhibitor of metalloproteinases-like, OB-fold / Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid / Immunoglobulin-like fold / Up-down Bundle / Mainly Alpha 類似検索 - ドメイン・相同性 polypeptide(D) / polypeptide(D) (> 10) / Complement C5 / Complement C5 類似検索 - 構成要素生物種 Rattus norvegicus (ドブネズミ)手法 X線回折 / 解像度 : 1.309 Å 詳細データ登録者 Zuo, C. 資金援助 中国, 4件 詳細 詳細を隠す組織 認可番号 国 National Natural Science Foundation of China 21532004 中国 National Natural Science Foundation of China 91753205 中国 National Natural Science Foundation of China 81621002 中国 National Natural Science Foundation of China 21621003 中国
引用ジャーナル : To Be Published タイトル : Chimeric protein probes for C5a receptors through fusion of anaphylatoxin C5a core region with a small-molecule antagonist著者 : Zuo, C. 履歴 登録 2019年4月16日 登録サイト : PDBJ / 処理サイト : PDBJ改定 1.0 2020年4月22日 Provider : repository / タイプ : Initial release改定 2.0 2023年11月15日 Group : Atomic model / Data collection ... Atomic model / Data collection / Database references / Derived calculations カテゴリ : atom_site / chem_comp_atom ... atom_site / chem_comp_atom / chem_comp_bond / database_2 / struct_conn Item : _atom_site.auth_atom_id / _atom_site.label_atom_id ... _atom_site.auth_atom_id / _atom_site.label_atom_id / _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.pdbx_dist_value / _struct_conn.pdbx_leaving_atom_flag / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_conn.ptnr2_symmetry