Entry Database : PDB / ID : 6j28 Structure visualization Downloads & linksTitle Crystal structure of the branched-chain polyamine synthase C9 mutein from Thermus thermophilus (Tth-BpsA C9) in complex with N4-aminopropylspermidine and 5'-methylthioadenosine ComponentsN(4)-bis(aminopropyl)spermidine synthase Details Keywords TRANSFERASE / N(4)-bis(aminopropyl)spermidine synthase / POLYAMINE BIOSYNTHESIS / SPERMIDINE / BRANCHED POLYAMINESFunction / homology Function and homology informationFunction Domain/homology Component
N4-bis(aminopropyl)spermidine synthase / polyamine biosynthetic process / transferase activity, transferring alkyl or aryl (other than methyl) groups / cytoplasm Similarity search - Function N(4)-bis(aminopropyl)spermidine synthase, C-terminal / N(4)-bis(aminopropyl)spermidine synthase / Branched-chain polyamine synthase A C-terminal domain / Vaccinia Virus protein VP39 / Winged helix-like DNA-binding domain superfamily / S-adenosyl-L-methionine-dependent methyltransferase superfamily / Rossmann fold / 3-Layer(aba) Sandwich / Alpha Beta Similarity search - Domain/homology : / 5'-DEOXY-5'-METHYLTHIOADENOSINE / N,N-bis(3-aminopropyl)butane-1,4-diamine / N(4)-bis(aminopropyl)spermidine synthase Similarity search - ComponentBiological species Thermus thermophilus (bacteria)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 1.9 Å DetailsAuthors Mizohata, E. / Toyoda, M. / Fujita, J. / Inoue, T. Funding support Japan, 1items Details Hide detailsOrganization Grant number Country Japan Science and Technology JPMJPR17GB Japan
CitationJournal : Febs J. / Year : 2019Title : The C-terminal flexible region of branched-chain polyamine synthase facilitates substrate specificity and catalysis.Authors : Hidese, R. / Toyoda, M. / Yoshino, K.I. / Fukuda, W. / Wihardja, G.A. / Kimura, S. / Fujita, J. / Niitsu, M. / Oshima, T. / Imanaka, T. / Mizohata, E. / Fujiwara, S. History Deposition Dec 31, 2018 Deposition site : PDBJ / Processing site : PDBJRevision 1.0 Jun 26, 2019 Provider : repository / Type : Initial releaseRevision 1.1 Oct 23, 2019 Group : Data collection / Database references / Category : citationItem : _citation.journal_volume / _citation.page_first / _citation.page_lastRevision 1.2 Mar 27, 2024 Group : Data collection / Database references / Derived calculationsCategory : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / struct_conn Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id
Show all Show less