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- PDB-6iyz: Structural basis for activity of TRIC counter-ion channels in cal... -
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Open data
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Basic information
Entry | Database: PDB / ID: 6iyz | |||||||||
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Title | Structural basis for activity of TRIC counter-ion channels in calcium release | |||||||||
![]() | Trimeric intracellular cation channel type A | |||||||||
![]() | MEMBRANE PROTEIN / TRIC / cation channel | |||||||||
Function / homology | TRIC channel / TRIC channel / potassium channel activity / sarcoplasmic reticulum membrane / nuclear membrane / identical protein binding / Trimeric intracellular cation channel type A![]() | |||||||||
Biological species | ![]() ![]() | |||||||||
Method | ![]() ![]() ![]() | |||||||||
![]() | Wang, X.H. / Zeng, Y. / Qin, L. / Gao, F. / Su, M. / Chen, Y.H. | |||||||||
Funding support | ![]()
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![]() | ![]() Title: Structural basis for activity of TRIC counter-ion channels in calcium release. Authors: Wang, X.H. / Su, M. / Gao, F. / Xie, W. / Zeng, Y. / Li, D.L. / Liu, X.L. / Zhao, H. / Qin, L. / Li, F. / Liu, Q. / Clarke, O.B. / Lam, S.M. / Shui, G.H. / Hendrickson, W.A. / Chen, Y.H. | |||||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 61.3 KB | Display | ![]() |
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PDB format | ![]() | 44.6 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Arichive directory | ![]() ![]() | HTTPS FTP |
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-Related structure data
Related structure data | ![]() 6iyuSC ![]() 6iyxC ![]() 6iz0C ![]() 6iz1C ![]() 6iz3C ![]() 6iz4C ![]() 6iz5C ![]() 6iz6C ![]() 6izfC S: Starting model for refinement C: citing same article ( |
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Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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1 | ![]()
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Unit cell |
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Components on special symmetry positions |
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Components
#1: Protein | Mass: 36957.551 Da / Num. of mol.: 1 / Mutation: C245S Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() | ||
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#2: Chemical | #3: Water | ChemComp-HOH / | |
-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 5.44 Å3/Da / Density % sol: 77.38 % |
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Crystal grow | Temperature: 278 K / Method: vapor diffusion, sitting drop / Details: NaH2PO4, K2HPO4, phosphate-citrate pH 4.2 |
-Data collection
Diffraction | Mean temperature: 100 K / Serial crystal experiment: N | ||||||||||||||||||||||||||||||
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Diffraction source | Source: ![]() ![]() ![]() | ||||||||||||||||||||||||||||||
Detector | Type: DECTRIS PILATUS 300K / Detector: PIXEL / Date: Jan 14, 2017 | ||||||||||||||||||||||||||||||
Radiation | Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray | ||||||||||||||||||||||||||||||
Radiation wavelength | Wavelength: 0.9785 Å / Relative weight: 1 | ||||||||||||||||||||||||||||||
Reflection | Resolution: 2.2→47.41 Å / Num. obs: 42420 / % possible obs: 100 % / Redundancy: 147.2 % / CC1/2: 0.999 / Rmerge(I) obs: 0.392 / Rpim(I) all: 0.032 / Rrim(I) all: 0.394 / Net I/σ(I): 24.3 / Num. measured all: 6242648 / Scaling rejects: 5 | ||||||||||||||||||||||||||||||
Reflection shell | Diffraction-ID: 1
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Processing
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Refinement | Method to determine structure: ![]() Starting model: 6IYU Resolution: 2.2→47.413 Å / SU ML: 0.32 / Cross valid method: THROUGHOUT / σ(F): 1.33 / Phase error: 29.41 / Stereochemistry target values: ML
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Solvent computation | Shrinkage radii: 0.9 Å / VDW probe radii: 1.11 Å / Solvent model: FLAT BULK SOLVENT MODEL | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Displacement parameters | Biso max: 137.89 Å2 / Biso mean: 60.6597 Å2 / Biso min: 33.02 Å2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refinement step | Cycle: final / Resolution: 2.2→47.413 Å
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LS refinement shell | Refine-ID: X-RAY DIFFRACTION / Rfactor Rfree error: 0 / Total num. of bins used: 16 / % reflection obs: 100 %
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