登録情報 | データベース: PDB / ID: 6isc |
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タイトル | complex structure of mCD226-ecto and hCD155-D1 |
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要素 | - CD226 antigen
- Poliovirus receptor
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キーワード | IMMUNE SYSTEM / complex structure / mCD226 / CD155 / NK cell receptor |
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機能・相同性 | 機能・相同性情報
positive regulation of Fc receptor mediated stimulatory signaling pathway / susceptibility to T cell mediated cytotoxicity / coreceptor-mediated virion attachment to host cell / establishment of mitochondrion localization / susceptibility to natural killer cell mediated cytotoxicity / positive regulation of immunoglobulin mediated immune response / Nectin/Necl trans heterodimerization / positive regulation of natural killer cell cytokine production / positive regulation of mast cell activation / regulation of viral entry into host cell ...positive regulation of Fc receptor mediated stimulatory signaling pathway / susceptibility to T cell mediated cytotoxicity / coreceptor-mediated virion attachment to host cell / establishment of mitochondrion localization / susceptibility to natural killer cell mediated cytotoxicity / positive regulation of immunoglobulin mediated immune response / Nectin/Necl trans heterodimerization / positive regulation of natural killer cell cytokine production / positive regulation of mast cell activation / regulation of viral entry into host cell / positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target / acrosome assembly / positive regulation of natural killer cell mediated cytotoxicity / apical junction complex / Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell / heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules / positive regulation of T cell receptor signaling pathway / homophilic cell adhesion via plasma membrane adhesion molecules / cell adhesion molecule binding / cytoskeleton organization / adherens junction / Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell / positive regulation of type II interferon production / integrin binding / virus receptor activity / signaling receptor activity / cell adhesion / fusion of virus membrane with host plasma membrane / external side of plasma membrane / focal adhesion / protein kinase binding / cell surface / extracellular space / extracellular exosome / identical protein binding / membrane / plasma membrane / cytoplasm類似検索 - 分子機能 CD226 antigen / CD80-like, immunoglobulin C2-set / CD80-like C2-set immunoglobulin domain / Immunoglobulin V-Type / Immunoglobulin V-set domain / Immunoglobulin V-set domain / Immunoglobulin subtype / Immunoglobulin / Ig-like domain profile. / Immunoglobulin-like domain ...CD226 antigen / CD80-like, immunoglobulin C2-set / CD80-like C2-set immunoglobulin domain / Immunoglobulin V-Type / Immunoglobulin V-set domain / Immunoglobulin V-set domain / Immunoglobulin subtype / Immunoglobulin / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / Immunoglobulins / Immunoglobulin-like fold / Immunoglobulin-like / Sandwich / Mainly Beta類似検索 - ドメイン・相同性 |
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生物種 | ![](img/tx_mammal.gif) Mus musculus (ハツカネズミ)
Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.2 Å |
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データ登録者 | Wang, H. / Qi, J. / Zhang, S. / Li, Y. / Tan, S. / Gao, G.F. |
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資金援助 | 中国, 2件 組織 | 認可番号 | 国 |
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National Natural Science Foundation of China | 31700149 | 中国 | National Natural Science Foundation of China | 31390432 | 中国 |
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引用 | ジャーナル: Proc. Natl. Acad. Sci. U.S.A. / 年: 2019 タイトル: Binding mode of the side-by-side two-IgV molecule CD226/DNAM-1 to its ligand CD155/Necl-5. 著者: Wang, H. / Qi, J. / Zhang, S. / Li, Y. / Tan, S. / Gao, G.F. |
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履歴 | 登録 | 2018年11月16日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
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改定 1.0 | 2018年12月26日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2019年2月13日 | Group: Data collection / Database references / カテゴリ: citation Item: _citation.journal_abbrev / _citation.journal_volume ..._citation.journal_abbrev / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year |
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改定 1.2 | 2020年7月29日 | Group: Data collection / Derived calculations / Structure summary カテゴリ: chem_comp / entity ...chem_comp / entity / pdbx_chem_comp_identifier / pdbx_entity_nonpoly / struct_conn / struct_site / struct_site_gen Item: _chem_comp.name / _chem_comp.type ..._chem_comp.name / _chem_comp.type / _entity.pdbx_description / _pdbx_entity_nonpoly.name / _struct_conn.pdbx_role 解説: Carbohydrate remediation / Provider: repository / タイプ: Remediation |
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改定 1.3 | 2023年11月22日 | Group: Data collection / Database references ...Data collection / Database references / Refinement description / Structure summary カテゴリ: chem_comp / chem_comp_atom ...chem_comp / chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _chem_comp.pdbx_synonyms / _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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