Entry Database : PDB / ID : 6ie3 Structure visualization Downloads & linksTitle Crystal structure of methyladenine demethylase ComponentsNucleic acid dioxygenase ALKBH1 Details Keywords OXIDOREDUCTASE / demethylase / DNA binding proteinFunction / homology Function and homology informationFunction Domain/homology Component
regulation of translational initiation by tRNA modification / DNA N6-methyladenine demethylase / regulation of translational elongation / 5-methylcytosine dioxygenase activity / tRNA demethylase activity / regulation of mitochondrial translation / tRNA wobble cytosine modification / DNA oxidative demethylase / : / oxidative RNA demethylation ... regulation of translational initiation by tRNA modification / DNA N6-methyladenine demethylase / regulation of translational elongation / 5-methylcytosine dioxygenase activity / tRNA demethylase activity / regulation of mitochondrial translation / tRNA wobble cytosine modification / DNA oxidative demethylase / : / oxidative RNA demethylation / oxidative RNA demethylase activity / broad specificity oxidative DNA demethylase activity / Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor / RNA repair / : / oxidative demethylation / 2-oxoglutarate-dependent dioxygenase activity / DNA alkylation repair / regulation of translational initiation / chemoattractant activity / developmental growth / class I DNA-(apurinic or apyrimidinic site) endonuclease activity / DNA-(apurinic or apyrimidinic site) lyase / neuron migration / euchromatin / ferrous iron binding / placenta development / neuron projection development / in utero embryonic development / negative regulation of neuron apoptotic process / tRNA binding / DNA repair / endoplasmic reticulum / mitochondrion / nucleoplasm / nucleus / cytoplasm Similarity search - Function Alkylated DNA repair protein AlkB / Alpha-ketoglutarate-dependent dioxygenase AlkB-like / 2OG-Fe(II) oxygenase superfamily / Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily / Oxoglutarate/iron-dependent dioxygenase / Fe(2+) 2-oxoglutarate dioxygenase domain profile. Similarity search - Domain/homologyBiological species Homo sapiens (human)Method X-RAY DIFFRACTION / SYNCHROTRON / SAD / Resolution : 1.97 Å DetailsAuthors Tian, L.F. / Tang, Q. / Chen, Z.Z. / Yan, X.X. CitationJournal : Cell Res. / Year : 2020Title : Structural basis of nucleic acid recognition and 6mA demethylation by human ALKBH1.Authors : Tian, L.F. / Liu, Y.P. / Chen, L. / Tang, Q. / Wu, W. / Sun, W. / Chen, Z. / Yan, X.X. History Deposition Sep 13, 2018 Deposition site : PDBJ / Processing site : PDBJRevision 1.0 Sep 18, 2019 Provider : repository / Type : Initial releaseRevision 1.1 Jul 8, 2020 Group : Database references / Category : citation / citation_authorItem : _citation.country / _citation.journal_abbrev ... _citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year Revision 1.2 Mar 27, 2024 Group : Data collection / Database references / Category : chem_comp_atom / chem_comp_bond / database_2Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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