登録情報 | データベース: PDB / ID: 6gxz |
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タイトル | Crystal structure of the human RPAP3(TPR2)-PIH1D1(CS) complex |
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要素 | - PIH1 domain-containing protein 1
- RNA polymerase II-associated protein 3
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キーワード | CHAPERONE / Cochaperone / Complex / TPR domain |
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機能・相同性 | 機能・相同性情報
TORC1 complex assembly / snoRNA localization / positive regulation of glucose mediated signaling pathway / pre-snoRNP complex / positive regulation of transcription of nucleolar large rRNA by RNA polymerase I / negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway / R2TP complex / RPAP3/R2TP/prefoldin-like complex / protein folding chaperone complex / box C/D snoRNP assembly ...TORC1 complex assembly / snoRNA localization / positive regulation of glucose mediated signaling pathway / pre-snoRNP complex / positive regulation of transcription of nucleolar large rRNA by RNA polymerase I / negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway / R2TP complex / RPAP3/R2TP/prefoldin-like complex / protein folding chaperone complex / box C/D snoRNP assembly / histone reader activity / epithelial cell differentiation / positive regulation of TORC1 signaling / phosphoprotein binding / positive regulation of protein serine/threonine kinase activity / rRNA processing / ATPase binding / histone binding / chromatin remodeling / protein stabilization / ribonucleoprotein complex / nucleolus / protein kinase binding / nucleus / cytoplasm / cytosol類似検索 - 分子機能 PIH1D1/2/3, CS-like domain / PIH1 CS-like domain / : / : / PIH1, N-terminal / PIH1 N-terminal domain / RNA-polymerase II-associated protein 3-like, C-terminal domain / Potential Monad-binding region of RPAP3 / Tetratricopeptide repeat / Tetratricopeptide repeat ...PIH1D1/2/3, CS-like domain / PIH1 CS-like domain / : / : / PIH1, N-terminal / PIH1 N-terminal domain / RNA-polymerase II-associated protein 3-like, C-terminal domain / Potential Monad-binding region of RPAP3 / Tetratricopeptide repeat / Tetratricopeptide repeat / Tetratricopeptide repeat / Tetratricopeptide repeat / TPR repeat region circular profile. / TPR repeat profile. / Tetratricopeptide repeats / Tetratricopeptide repeat / Tetratricopeptide-like helical domain superfamily類似検索 - ドメイン・相同性 RNA polymerase II-associated protein 3 / PIH1 domain-containing protein 1類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.965 Å |
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データ登録者 | Henri, J. / Quinternet, M. / Manival, X. / Chagot, M.-E. / Charpentier, B. / Meyer, P. |
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資金援助 | フランス, 2件 組織 | 認可番号 | 国 |
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French National Research Agency | ANR-AA-BSV8-01503 | フランス | French National Research Agency | ANR-16-CE11-0032-02 | フランス |
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引用 | ジャーナル: Structure / 年: 2018 タイトル: Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex. 著者: Henri, J. / Chagot, M.E. / Bourguet, M. / Abel, Y. / Terral, G. / Maurizy, C. / Aigueperse, C. / Georgescauld, F. / Vandermoere, F. / Saint-Fort, R. / Behm-Ansmant, I. / Charpentier, B. / ...著者: Henri, J. / Chagot, M.E. / Bourguet, M. / Abel, Y. / Terral, G. / Maurizy, C. / Aigueperse, C. / Georgescauld, F. / Vandermoere, F. / Saint-Fort, R. / Behm-Ansmant, I. / Charpentier, B. / Pradet-Balade, B. / Verheggen, C. / Bertrand, E. / Meyer, P. / Cianferani, S. / Manival, X. / Quinternet, M. |
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履歴 | 登録 | 2018年6月27日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2018年8月8日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2018年9月12日 | Group: Data collection / Database references / カテゴリ: citation Item: _citation.journal_volume / _citation.page_first / _citation.page_last |
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改定 1.2 | 2018年10月3日 | Group: Data collection / カテゴリ: diffrn_source Item: _diffrn_source.pdbx_synchrotron_beamline / _diffrn_source.type |
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改定 1.3 | 2024年1月17日 | Group: Advisory / Data collection ...Advisory / Data collection / Database references / Derived calculations / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_unobs_or_zero_occ_atoms / struct_conn Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id |
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