登録情報 データベース : PDB / ID : 6eoc 構造の表示 ダウンロードとリンクタイトル Crystal structure of AMPylated GRP78 in apo form (Crystal form 2) 要素78 kDa glucose-regulated protein 詳細 キーワード CHAPERONE / GRP78 / BIP / AMPylation / apo機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
negative regulation of IRE1-mediated unfolded protein response / endoplasmic reticulum chaperone complex / post-translational protein targeting to membrane, translocation / non-chaperonin molecular chaperone ATPase / negative regulation of protein-containing complex assembly / endoplasmic reticulum unfolded protein response / ATP-dependent protein folding chaperone / negative regulation of cysteine-type endopeptidase activity involved in apoptotic process / melanosome / endoplasmic reticulum lumen ... negative regulation of IRE1-mediated unfolded protein response / endoplasmic reticulum chaperone complex / post-translational protein targeting to membrane, translocation / non-chaperonin molecular chaperone ATPase / negative regulation of protein-containing complex assembly / endoplasmic reticulum unfolded protein response / ATP-dependent protein folding chaperone / negative regulation of cysteine-type endopeptidase activity involved in apoptotic process / melanosome / endoplasmic reticulum lumen / endoplasmic reticulum membrane / negative regulation of apoptotic process / perinuclear region of cytoplasm / cell surface / ATP hydrolysis activity / mitochondrion / ATP binding / nucleus / cytosol 類似検索 - 分子機能 Endoplasmic reticulum chaperone BIP, nucleotide-binding domain / Substrate Binding Domain Of DNAk; Chain A, domain 1 / Substrate Binding Domain Of DNAk; Chain A, domain 1 / Endoplasmic reticulum targeting sequence. / Heat shock hsp70 proteins family signature 2. / Heat shock hsp70 proteins family signature 1. / Heat shock hsp70 proteins family signature 3. / Heat shock protein 70, conserved site / Heat shock protein 70kD, peptide-binding domain superfamily / Heat shock protein 70 family ... Endoplasmic reticulum chaperone BIP, nucleotide-binding domain / Substrate Binding Domain Of DNAk; Chain A, domain 1 / Substrate Binding Domain Of DNAk; Chain A, domain 1 / Endoplasmic reticulum targeting sequence. / Heat shock hsp70 proteins family signature 2. / Heat shock hsp70 proteins family signature 1. / Heat shock hsp70 proteins family signature 3. / Heat shock protein 70, conserved site / Heat shock protein 70kD, peptide-binding domain superfamily / Heat shock protein 70 family / Hsp70 protein / Heat shock protein 70kD, C-terminal domain superfamily / ATPase, substrate binding domain, subdomain 4 / Actin; Chain A, domain 4 / ATPase, nucleotide binding domain / ATPase, nucleotide binding domain / Nucleotidyltransferase; domain 5 / Alpha-Beta Complex / Sandwich / 2-Layer Sandwich / Mainly Beta / Alpha Beta 類似検索 - ドメイン・相同性 CITRATE ANION / Endoplasmic reticulum chaperone BiP 類似検索 - 構成要素生物種 Cricetulus griseus (モンゴルキヌゲネズミ)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 1.67 Å 詳細データ登録者 Yan, Y. / Preissler, S. / Ron, D. / Read, R.J. 資金援助 英国, 3件 詳細 詳細を隠す組織 認可番号 国 Wellcome Trust 200848/Z/16/Z 英国 Wellcome Trust 082961/Z/07/Z 英国 British Heart Foundation PG/12/41/29679 英国
引用ジャーナル : Elife / 年 : 2017タイトル : AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation.著者 : Preissler, S. / Rohland, L. / Yan, Y. / Chen, R. / Read, R.J. / Ron, D. 履歴 登録 2017年10月9日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2017年11月1日 Provider : repository / タイプ : Initial release改定 1.1 2018年11月7日 Group : Data collection / Source and taxonomy / カテゴリ : entity_src_genItem : _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id / _entity_src_gen.pdbx_host_org_scientific_name改定 1.2 2024年1月17日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / software Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _software.name
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