登録情報 | データベース: PDB / ID: 6d2k |
---|
タイトル | Crystal structure of the FERM domain of mouse FARP2 |
---|
要素 | FERM, ARHGEF and pleckstrin domain-containing protein 2 |
---|
キーワード | SIGNALING PROTEIN / membrane targeting |
---|
機能・相同性 | 機能・相同性情報
regulation of integrin activation / hair cycle process / RAC1 GTPase cycle / SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion / podosome assembly / neuron remodeling / Rac protein signal transduction / semaphorin-plexin signaling pathway / cytoskeletal protein binding / osteoclast differentiation ...regulation of integrin activation / hair cycle process / RAC1 GTPase cycle / SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion / podosome assembly / neuron remodeling / Rac protein signal transduction / semaphorin-plexin signaling pathway / cytoskeletal protein binding / osteoclast differentiation / guanyl-nucleotide exchange factor activity / actin cytoskeleton organization / cytoskeleton / cell adhesion / cytosol / cytoplasm類似検索 - 分子機能 : / FARP1/FARP2/FRMD7, FERM domain C-lobe / FERM adjacent (FA) / FERM adjacent (FA) / FERM adjacent (FA) / Acyl-CoA Binding Protein - #10 / Ezrin/radixin/moesin-like / Acyl-CoA Binding Protein / FERM, C-terminal PH-like domain / FERM C-terminal PH-like domain ...: / FARP1/FARP2/FRMD7, FERM domain C-lobe / FERM adjacent (FA) / FERM adjacent (FA) / FERM adjacent (FA) / Acyl-CoA Binding Protein - #10 / Ezrin/radixin/moesin-like / Acyl-CoA Binding Protein / FERM, C-terminal PH-like domain / FERM C-terminal PH-like domain / FERM C-terminal PH-like domain / FERM, N-terminal / FERM N-terminal domain / FERM domain signature 1. / FERM conserved site / Dbl homology (DH) domain superfamily / RhoGEF domain / Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases / Dbl homology (DH) domain / FERM central domain / Dbl homology (DH) domain profile. / FERM/acyl-CoA-binding protein superfamily / Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) / PH-domain like / FERM central domain / FERM superfamily, second domain / FERM domain / FERM domain profile. / Band 4.1 domain / Band 4.1 homologues / PH domain / Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 / PH domain profile. / Pleckstrin homology domain. / Pleckstrin homology domain / Ubiquitin-like (UB roll) / PH-like domain superfamily / Ubiquitin-like domain superfamily / Roll / Roll / Up-down Bundle / Mainly Beta / Mainly Alpha / Alpha Beta類似検索 - ドメイン・相同性 FERM, ARHGEF and pleckstrin domain-containing protein 2類似検索 - 構成要素 |
---|
生物種 | ![](img/tx_mammal.gif) Mus musculus (ハツカネズミ) |
---|
手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.55 Å |
---|
データ登録者 | He, X. / Zhang, X. |
---|
資金援助 | 米国, 中国, 3件 組織 | 認可番号 | 国 |
---|
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | GM088197 | 米国 | Welch Foundation | I-1702 | 米国 | National Natural Science Foundation of China (NSFC) | #31500605 | 中国 |
|
---|
引用 | ジャーナル: Sci Rep / 年: 2018 タイトル: Structural analyses of FERM domain-mediated membrane localization of FARP1. 著者: Kuo, Y.C. / He, X. / Coleman, A.J. / Chen, Y.J. / Dasari, P. / Liou, J. / Biederer, T. / Zhang, X. |
---|
履歴 | 登録 | 2018年4月13日 | 登録サイト: RCSB / 処理サイト: RCSB |
---|
改定 1.0 | 2018年7月18日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2020年1月1日 | Group: Author supporting evidence / カテゴリ: pdbx_audit_support / Item: _pdbx_audit_support.funding_organization |
---|
改定 1.2 | 2023年10月4日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
---|
|
---|