Entry | Database: PDB / ID: 6a04 |
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Title | Structure of pSTING complex |
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Components | Stimulator of interferon genes protein |
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Keywords | SIGNALING PROTEIN / pSTING |
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Function / homology | Function and homology information
proton channel activity / 2',3'-cyclic GMP-AMP binding / cyclic-di-GMP binding / cGAS/STING signaling pathway / reticulophagy / autophagosome membrane / positive regulation of macroautophagy / autophagosome assembly / autophagosome / positive regulation of type I interferon production ...proton channel activity / 2',3'-cyclic GMP-AMP binding / cyclic-di-GMP binding / cGAS/STING signaling pathway / reticulophagy / autophagosome membrane / positive regulation of macroautophagy / autophagosome assembly / autophagosome / positive regulation of type I interferon production / signaling adaptor activity / activation of innate immune response / positive regulation of interferon-beta production / endoplasmic reticulum-Golgi intermediate compartment membrane / cytoplasmic vesicle / defense response to virus / mitochondrial outer membrane / Golgi membrane / innate immune response / endoplasmic reticulum membrane / perinuclear region of cytoplasm / protein homodimerization activity / plasma membrane / cytoplasmSimilarity search - Function Stimulator of interferon genes protein / : / Stimulator of interferon genes protein / Stimulator of interferon genes protein, C-terminal domain superfamily / Transmembrane protein 173 / Rossmann fold / 3-Layer(aba) Sandwich / Alpha BetaSimilarity search - Domain/homology |
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Biological species | ![](img/tx_mammal.gif) Sus scrofa (pig) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / Resolution: 1.9 Å |
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Authors | Yuan, Z.L. / Shang, G.J. / Cong, X.Y. / Gu, L.C. |
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Funding support | 1items Organization | Grant number | Country |
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National Natural Science Foundation of China | | |
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Citation | Journal: J.Biol.Chem. / Year: 2019 Title: Crystal structures of porcine STINGCBD-CDN complexes reveal the mechanism of ligand recognition and discrimination of STING proteins. Authors: Cong, X. / Yuan, Z. / Du, Y. / Wu, B. / Lu, D. / Wu, X. / Zhang, Y. / Li, F. / Wei, B. / Li, J. / Wu, J. / Xu, S. / Wang, J. / Qi, J. / Shang, G. / Gu, L. |
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History | Deposition | Jun 5, 2018 | Deposition site: PDBJ / Processing site: PDBJ |
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Revision 1.0 | Jun 19, 2019 | Provider: repository / Type: Initial release |
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Revision 1.1 | Aug 7, 2019 | Group: Data collection / Database references / Category: citation Item: _citation.journal_volume / _citation.page_first / _citation.page_last |
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Revision 1.2 | Mar 27, 2024 | Group: Data collection / Database references / Structure summary Category: chem_comp / chem_comp_atom ...chem_comp / chem_comp_atom / chem_comp_bond / database_2 Item: _chem_comp.pdbx_synonyms / _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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