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- PDB-5znf: ALTERNATING ZINC FINGERS IN THE HUMAN MALE ASSOCIATED PROTEIN ZFY... -
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Open data
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Basic information
Entry | Database: PDB / ID: 5znf | ||||||
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Title | ALTERNATING ZINC FINGERS IN THE HUMAN MALE ASSOCIATED PROTEIN ZFY: 2D NMR STRUCTURE OF AN EVEN FINGER AND IMPLICATIONS FOR "JUMPING-LINKER" DNA RECOGNITION | ||||||
![]() | ZINC FINGER | ||||||
![]() | ZINC FINGER DNA BINDING DOMAIN | ||||||
Function / homology | ![]() DNA-binding transcription repressor activity, RNA polymerase II-specific / DNA-binding transcription activator activity, RNA polymerase II-specific / sequence-specific DNA binding / DNA-binding transcription factor activity, RNA polymerase II-specific / RNA polymerase II cis-regulatory region sequence-specific DNA binding / chromatin / nucleolus / regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / nucleoplasm ...DNA-binding transcription repressor activity, RNA polymerase II-specific / DNA-binding transcription activator activity, RNA polymerase II-specific / sequence-specific DNA binding / DNA-binding transcription factor activity, RNA polymerase II-specific / RNA polymerase II cis-regulatory region sequence-specific DNA binding / chromatin / nucleolus / regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / nucleoplasm / nucleus / metal ion binding Similarity search - Function | ||||||
Biological species | ![]() | ||||||
Method | SOLUTION NMR | ||||||
![]() | Kochoyan, M. / Keutmann, H.T. / Weiss, M.A. | ||||||
![]() | ![]() Title: Alternating zinc fingers in the human male associated protein ZFY: 2D NMR structure of an even finger and implications for "jumping-linker" DNA recognition. Authors: Kochoyan, M. / Havel, T.F. / Nguyen, D.T. / Dahl, C.E. / Keutmann, H.T. / Weiss, M.A. #1: ![]() Title: Alternating Zinc Fingers in the Human Male Associated Protein Zfy: Refinement of the NMR Structure of an Even Finger by Selective Deuterium Labeling and Implications for DNA Recognition Authors: Kochoyan, M. / Keutmann, H.T. / Weiss, M.A. #2: ![]() Title: Architectural Rules of the Zinc-Finger Motif: Comparative Two-Dimensional NMR Studies of Native and "Aromatic-Swap" Domains Define a "Weakly Polar Switch" Authors: Kochoyan, M. / Keutmann, H.T. / Weiss, M.A. | ||||||
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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PDBx/mmCIF format | ![]() | 134 KB | Display | ![]() |
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PDB format | ![]() | 108.9 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
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-Validation report
Summary document | ![]() | 348.7 KB | Display | ![]() |
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Full document | ![]() | 423 KB | Display | |
Data in XML | ![]() | 8.2 KB | Display | |
Data in CIF | ![]() | 13.2 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
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Links
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Assembly
Deposited unit | ![]()
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NMR ensembles |
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Components
#1: Protein/peptide | Mass: 3615.080 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() |
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#2: Chemical | ChemComp-ZN / |
-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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Processing
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NMR software |
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NMR ensemble | Conformers submitted total number: 13 |