Entry Database : PDB / ID : 5vzx Structure visualization Downloads & linksTitle Crystal structure of crenezumab Fab Components(Crenezumab Fab ...) x 2 Details Keywords IMMUNE SYSTEM / immunoglobulinFunction / homology Function and homology informationFunction Domain/homology Component
immunoglobulin complex, circulating / immunoglobulin receptor binding / complement activation, classical pathway / antigen binding / antibacterial humoral response / blood microparticle / immune response / extracellular space / extracellular exosome / plasma membrane Similarity search - Function : / : / Immunoglobulin V-Type / Immunoglobulin V-set domain / Immunoglobulin V-set domain / Immunoglobulin/major histocompatibility complex, conserved site / Immunoglobulin subtype / Immunoglobulin / Immunoglobulins and major histocompatibility complex proteins signature. / Immunoglobulin C-Type ... : / : / Immunoglobulin V-Type / Immunoglobulin V-set domain / Immunoglobulin V-set domain / Immunoglobulin/major histocompatibility complex, conserved site / Immunoglobulin subtype / Immunoglobulin / Immunoglobulins and major histocompatibility complex proteins signature. / Immunoglobulin C-Type / Immunoglobulin C1-set / Immunoglobulin C1-set domain / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / Immunoglobulins / Immunoglobulin-like fold / Immunoglobulin-like / Sandwich / Mainly Beta Similarity search - Domain/homologyBiological species Homo sapiens (human)Method X-RAY DIFFRACTION / SYNCHROTRON / Resolution : 2.501 Å DetailsAuthors Ultsch, M. / Wang, W. CitationJournal : Sci Rep / Year : 2016Title : Structure of Crenezumab Complex with Abeta Shows Loss of beta-Hairpin.Authors: Ultsch, M. / Li, B. / Maurer, T. / Mathieu, M. / Adolfsson, O. / Muhs, A. / Pfeifer, A. / Pihlgren, M. / Bainbridge, T.W. / Reichelt, M. / Ernst, J.A. / Eigenbrot, C. / Fuh, G. / Atwal, J.K. ... Authors : Ultsch, M. / Li, B. / Maurer, T. / Mathieu, M. / Adolfsson, O. / Muhs, A. / Pfeifer, A. / Pihlgren, M. / Bainbridge, T.W. / Reichelt, M. / Ernst, J.A. / Eigenbrot, C. / Fuh, G. / Atwal, J.K. / Watts, R.J. / Wang, W. History Deposition May 29, 2017 Deposition site : RCSB / Processing site : RCSBSupersession Aug 9, 2017 ID : 5KMV Revision 1.0 Aug 9, 2017 Provider : repository / Type : Initial release