登録情報 | データベース: PDB / ID: 5v0w |
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タイトル | Crystal structure of glycylpeptide N-tetradecanoyltransferase from Plasmodium vivax in complex with inhibitor IMP-0001088 |
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要素 | Glycylpeptide N-tetradecanoyltransferase |
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キーワード | TRANSFERASE/TRANSFERASE INHIBITOR / SSGCID / glycylpeptide N-tetradecanoyltransferase / N-myristoyltransferase / NMT / Plasmodium vival / Salvador I / Structural Genomics / Seattle Structural Genomics Center for Infectious Disease / TRANSFERASE-TRANSFERASE INHIBITOR complex |
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機能・相同性 | 機能・相同性情報
glycylpeptide N-tetradecanoyltransferase / glycylpeptide N-tetradecanoyltransferase activity / metal ion binding / cytoplasm類似検索 - 分子機能 Aminopeptidase - #170 / Glycylpeptide N-tetradecanoyltransferase, conserved site / Myristoyl-CoA:protein N-myristoyltransferase signature 1. / Myristoyl-CoA:protein N-myristoyltransferase signature 2. / Glycylpeptide N-tetradecanoyltransferase / Glycylpeptide N-tetradecanoyltransferase, N-terminal / Glycylpeptide N-tetradecanoyltransferase, C-terminal / Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain / Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain / Acyl-CoA N-acyltransferase ...Aminopeptidase - #170 / Glycylpeptide N-tetradecanoyltransferase, conserved site / Myristoyl-CoA:protein N-myristoyltransferase signature 1. / Myristoyl-CoA:protein N-myristoyltransferase signature 2. / Glycylpeptide N-tetradecanoyltransferase / Glycylpeptide N-tetradecanoyltransferase, N-terminal / Glycylpeptide N-tetradecanoyltransferase, C-terminal / Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain / Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain / Acyl-CoA N-acyltransferase / Aminopeptidase / 3-Layer(aba) Sandwich / Alpha Beta類似検索 - ドメイン・相同性 Chem-KFK / TETRADECANOYL-COA / Glycylpeptide N-tetradecanoyltransferase / Glycylpeptide N-tetradecanoyltransferase類似検索 - 構成要素 |
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生物種 |  Plasmodium vivax (マラリア 病原虫) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.8 Å |
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データ登録者 | Seattle Structural Genomics Center for Infectious Disease (SSGCID) |
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引用 | ジャーナル: Acta Crystallogr.,Sect.F / 年: 2025 タイトル: Structure of Plasmodium vivax N-myristoyltransferase with inhibitor IMP-1088: exploring an NMT inhibitor for antimalarial therapy 著者: Mendez, A. / Bolling, C. / Taylor, S. / Makumire, S. / Staker, B. / Reers, A. / Hammerson, B. / Mayclin, S.J. / Abendroth, J. / Lorimer, D.D. / Edwards, T.E. / Tate, E.W. / Subramanian, S. / ...著者: Mendez, A. / Bolling, C. / Taylor, S. / Makumire, S. / Staker, B. / Reers, A. / Hammerson, B. / Mayclin, S.J. / Abendroth, J. / Lorimer, D.D. / Edwards, T.E. / Tate, E.W. / Subramanian, S. / Bell, A.S. / Myler, P.J. / Asojo, O.A. / Chakafana, G. |
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履歴 | 登録 | 2017年2月28日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2018年3月7日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2023年10月4日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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改定 1.2 | 2025年1月15日 | Group: Database references / Structure summary カテゴリ: citation / citation_author / pdbx_entry_details Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.title / _citation.year |
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