Entry Database : PDB / ID : 5tg4 Structure visualization Downloads & linksTitle OXA-24/40 in Complex with Boronic Acid BA16 ComponentsBeta-lactamase Details Keywords hydrolase/hydrolase inhibitor / Inhibitor / Complex / Lactamase / OXA / hydrolase-hydrolase inhibitor complexFunction / homology Function and homology informationFunction Domain/homology Component
Penicillin-binding protein, transpeptidase / Penicillin binding protein transpeptidase domain / Beta-lactamase / DD-peptidase/beta-lactamase superfamily / Beta-lactamase/transpeptidase-like / Prokaryotic membrane lipoprotein lipid attachment site profile. / 3-Layer(aba) Sandwich / Alpha Beta Similarity search - Domain/homologyBiological species Acinetobacter baumannii (bacteria)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 1.44 Å DetailsAuthors Powers, R.A. / Werner, J.P. / Mitchell, J.M. Funding support United States, 1items Details Hide detailsOrganization Grant number Country National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) 2R15AI094489 United States
CitationJournal : Protein Sci. / Year : 2017Title : Exploring the potential of boronic acids as inhibitors of OXA-24/40 beta-lactamase.Authors : Werner, J.P. / Mitchell, J.M. / Taracila, M.A. / Bonomo, R.A. / Powers, R.A. History Deposition Sep 27, 2016 Deposition site : RCSB / Processing site : RCSBRevision 1.0 Jan 11, 2017 Provider : repository / Type : Initial releaseRevision 1.1 Mar 8, 2017 Group : Database referencesRevision 1.2 Sep 20, 2017 Group : Author supporting evidence / Category : pdbx_audit_supportItem : _pdbx_audit_support.funding_organization / _pdbx_audit_support.grant_numberRevision 1.3 Dec 11, 2019 Group : Author supporting evidence / Category : pdbx_audit_support / Item : _pdbx_audit_support.funding_organizationRevision 2.0 Jul 8, 2020 Group : Atomic model / Derived calculations / Structure summaryCategory : atom_site / atom_site_anisotrop ... atom_site / atom_site_anisotrop / chem_comp / entity / pdbx_entity_nonpoly Item : _atom_site.auth_atom_id / _atom_site.label_atom_id ... _atom_site.auth_atom_id / _atom_site.label_atom_id / _atom_site_anisotrop.pdbx_auth_atom_id / _atom_site_anisotrop.pdbx_label_atom_id / _chem_comp.name / _chem_comp.pdbx_synonyms / _chem_comp.type / _entity.pdbx_description / _pdbx_entity_nonpoly.name Revision 2.1 Oct 4, 2023 Group : Data collection / Database references / Refinement descriptionCategory : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accessionRevision 2.2 Nov 15, 2023 Group : Data collection / Category : chem_comp_atom / chem_comp_bond / Item : _chem_comp_atom.atom_id / _chem_comp_bond.atom_id_2
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