登録情報 | データベース: PDB / ID: 5s4v |
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タイトル | Tubulin-Z57040482-complex |
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要素 | - Stathmin-4
- Tubulin alpha-1B chain
- Tubulin beta-2B chain
- Tubulin-Tyrosine Ligase
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キーワード | CELL CYCLE / TUBULIN FOLD / CYTOSKELETON / MICROTUBULE |
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機能・相同性 | 機能・相同性情報
tubulin-tyrosine ligase activity / positive regulation of axon guidance / microtubule depolymerization / microtubule-based process / regulation of microtubule polymerization or depolymerization / tubulin binding / spindle microtubule / 加水分解酵素; 酸無水物に作用; GTPに作用・細胞または細胞小器官の運動に関与 / protein modification process / structural constituent of cytoskeleton ...tubulin-tyrosine ligase activity / positive regulation of axon guidance / microtubule depolymerization / microtubule-based process / regulation of microtubule polymerization or depolymerization / tubulin binding / spindle microtubule / 加水分解酵素; 酸無水物に作用; GTPに作用・細胞または細胞小器官の運動に関与 / protein modification process / structural constituent of cytoskeleton / microtubule cytoskeleton organization / microtubule cytoskeleton / neuron projection development / mitotic cell cycle / nervous system development / growth cone / microtubule / neuron projection / protein heterodimerization activity / nucleotide binding / GTPase activity / GTP binding / Golgi apparatus / metal ion binding / cytosol / cytoplasm類似検索 - 分子機能 Tubulin-tyrosine ligase/Tubulin polyglutamylase / Tubulin-tyrosine ligase family / TTL domain profile. / Stathmin family / Stathmin, conserved site / Stathmin superfamily / Stathmin family / Stathmin family signature 1. / Stathmin family signature 2. / Stathmin-like (SLD) domain profile. ...Tubulin-tyrosine ligase/Tubulin polyglutamylase / Tubulin-tyrosine ligase family / TTL domain profile. / Stathmin family / Stathmin, conserved site / Stathmin superfamily / Stathmin family / Stathmin family signature 1. / Stathmin family signature 2. / Stathmin-like (SLD) domain profile. / Alpha tubulin / Tubulin-beta mRNA autoregulation signal. / Beta tubulin, autoregulation binding site / Beta tubulin / Tubulin / Tubulin, C-terminal / Tubulin C-terminal domain / Tubulin, conserved site / Tubulin subunits alpha, beta, and gamma signature. / Tubulin/FtsZ family, C-terminal domain / Tubulin/FtsZ-like, C-terminal domain / Tubulin/FtsZ, C-terminal / Tubulin/FtsZ, 2-layer sandwich domain / Tubulin/FtsZ family, GTPase domain / Tubulin/FtsZ family, GTPase domain / Tubulin/FtsZ, GTPase domain / Tubulin/FtsZ, GTPase domain superfamily類似検索 - ドメイン・相同性 N-(2-hydroxyphenyl)acetamide / PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER / GUANOSINE-5'-DIPHOSPHATE / GUANOSINE-5'-TRIPHOSPHATE / Tubulin tyrosine ligase / Stathmin-4 / Tubulin alpha-1B chain / Tubulin beta-2B chain類似検索 - 構成要素 |
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生物種 | ![](img/tx_mammal.gif) Rattus norvegicus (ドブネズミ)
![](img/tx_bird.gif) Gallus gallus (ニワトリ)
![](img/tx_mammal.gif) Bos taurus (ウシ) |
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手法 | X線回折 / シンクロトロン / フーリエ合成 / 解像度: 2.3 Å |
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データ登録者 | Muehlethaler, T. / Gioia, D. / Prota, A.E. / Sharpe, M.E. / Cavalli, A. / Steinmetz, M.O. |
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資金援助 | European Union, イタリア, スイス, 4件 組織 | 認可番号 | 国 |
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iNEXT/Horizon 2020 | PID2692 | European Union | NEON/Regione Lombardia | ID239047 | イタリア | Swiss National Science Foundation | 31003A_166608 | スイス | Swiss National Science Foundation | 31030A_192566 | スイス |
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引用 | ジャーナル: Angew.Chem.Int.Ed.Engl. / 年: 2021 タイトル: Comprehensive Analysis of Binding Sites in Tubulin. 著者: Muhlethaler, T. / Gioia, D. / Prota, A.E. / Sharpe, M.E. / Cavalli, A. / Steinmetz, M.O. |
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履歴 | 登録 | 2020年11月8日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2021年6月30日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2024年3月6日 | Group: Advisory / Data collection / Database references カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_unobs_or_zero_occ_atoms Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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