登録情報 データベース : PDB / ID : 5lnc 構造の表示 ダウンロードとリンクタイトル Structure of SPX domain of the yeast inorganic polyphophate polymerase Vtc4 crystallized by carrier-driven crystallization in fusion with the macro domain of human histone macroH2A1.1 要素Vacuolar transporter chaperone 4,Core histone macro-H2A.1 詳細 キーワード HYDROLASE / macro domain / spx domain / inositol polyphosphate binding / carrier-driven crystallization機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
vacuolar transporter chaperone complex / negative regulation of cell cycle G2/M phase transition / negative regulation of protein localization to chromosome, telomeric region / regulation of NAD metabolic process / ATP-polyphosphate phosphotransferase / positive regulation of response to oxidative stress / polyphosphate biosynthetic process / positive regulation of maintenance of mitotic sister chromatid cohesion / engulfment of target by autophagosome / regulation of response to oxidative stress ... vacuolar transporter chaperone complex / negative regulation of cell cycle G2/M phase transition / negative regulation of protein localization to chromosome, telomeric region / regulation of NAD metabolic process / ATP-polyphosphate phosphotransferase / positive regulation of response to oxidative stress / polyphosphate biosynthetic process / positive regulation of maintenance of mitotic sister chromatid cohesion / engulfment of target by autophagosome / regulation of response to oxidative stress / ADP-D-ribose binding / polyphosphate kinase activity / ADP-D-ribose modification-dependent protein binding / negative regulation of transcription of nucleolar large rRNA by RNA polymerase I / sex chromatin / microautophagy / vacuole fusion, non-autophagic / sex-chromosome dosage compensation / polyphosphate metabolic process / positive regulation of endodermal cell differentiation / establishment of protein localization to chromatin / double-stranded methylated DNA binding / Barr body / rDNA binding / inositol hexakisphosphate binding / vacuolar transport / negative regulation of protein serine/threonine kinase activity / regulation of oxidative phosphorylation / positive regulation of keratinocyte differentiation / poly-ADP-D-ribose modification-dependent protein binding / protein serine/threonine kinase inhibitor activity / negative regulation of response to oxidative stress / vacuolar membrane / nuclear chromosome / fungal-type vacuole membrane / negative regulation of gene expression, epigenetic / site of DNA damage / autophagosome membrane / regulation of lipid metabolic process / pericentric heterochromatin / condensed chromosome / nucleosomal DNA binding / epigenetic regulation of gene expression / transcription initiation-coupled chromatin remodeling / cell periphery / promoter-specific chromatin binding / RNA polymerase II transcription regulatory region sequence-specific DNA binding / heterochromatin formation / chromatin DNA binding / structural constituent of chromatin / nucleosome / nucleosome assembly / cell cortex / cytoplasmic vesicle / chromosome, telomeric region / calmodulin binding / transcription cis-regulatory region binding / protein heterodimerization activity / DNA repair / endoplasmic reticulum membrane / chromatin / nucleolus / protein kinase binding / negative regulation of transcription by RNA polymerase II / enzyme binding / endoplasmic reticulum / DNA binding / extracellular exosome / nucleoplasm / nucleus 類似検索 - 分子機能 VTC domain superfamily / : / Domain of unknown function DUF202 / VTC domain / Domain of unknown function (DUF202) / VTC domain / Core histone macro-H2A / Core histone macro-H2A, macro domain / SPX domain / SPX domain profile. ... VTC domain superfamily / : / Domain of unknown function DUF202 / VTC domain / Domain of unknown function (DUF202) / VTC domain / Core histone macro-H2A / Core histone macro-H2A, macro domain / SPX domain / SPX domain profile. / Histone H2A, C-terminal domain / C-terminus of histone H2A / Histone H2A / Histone 2A / Histone H2A/H2B/H3 / Core histone H2A/H2B/H3/H4 / Histone-fold / Macro domain / Appr-1"-p processing enzyme / Macro domain / Macro domain profile. / Macro domain-like 類似検索 - ドメイン・相同性 Core histone macro-H2A.1 / Vacuolar transporter chaperone complex subunit 4 類似検索 - 構成要素生物種 Saccharomyces cerevisiae (パン酵母)Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 3.29 Å 詳細データ登録者 Wild, R. / Hothorn, M. 資金援助 スイス, 1件 詳細 詳細を隠す組織 認可番号 国 European Research Council 310856 スイス
引用ジャーナル : Protein Sci. / 年 : 2017タイトル : The macro domain as fusion tag for carrier-driven crystallization.著者 : Wild, R. / Hothorn, M. 履歴 登録 2016年8月3日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2016年11月9日 Provider : repository / タイプ : Initial release改定 1.1 2017年2月8日 Group : Database references改定 1.2 2024年1月10日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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