登録情報 | データベース: PDB / ID: 5l84 |
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タイトル | Structure of the H959F variant of the PpsC dehydratase domain from Mycobacterium tuberculosis |
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要素 | Phthiocerol synthesis polyketide synthase type I PpsC |
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キーワード | TRANSFERASE / dehydratase / polyketide / complex / tuberculosis |
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機能・相同性 | 機能・相同性情報
(phenol)carboxyphthiodiolenone synthase / phthiocerol biosynthetic process / phenolic phthiocerol biosynthetic process / polyketide synthase complex / Actinobacterium-type cell wall biogenesis / DIM/DIP cell wall layer assembly / fatty acid synthase activity / secondary metabolite biosynthetic process / phosphopantetheine binding / 3-oxoacyl-[acyl-carrier-protein] synthase activity ...(phenol)carboxyphthiodiolenone synthase / phthiocerol biosynthetic process / phenolic phthiocerol biosynthetic process / polyketide synthase complex / Actinobacterium-type cell wall biogenesis / DIM/DIP cell wall layer assembly / fatty acid synthase activity / secondary metabolite biosynthetic process / phosphopantetheine binding / 3-oxoacyl-[acyl-carrier-protein] synthase activity / fatty acid biosynthetic process / oxidoreductase activity / plasma membrane / cytoplasm / cytosol類似検索 - 分子機能 Polyketide synthase dehydratase / Zinc-binding dehydrogenase / : / : / Polyketide synthase dehydratase domain / : / Polyketide and metazoan fatty acid synthase dehydratase (PKS/mFAS DH) domain profile. / Polyketide synthase dehydratase N-terminal domain / PKS_DH / Polyketide synthase, dehydratase domain ...Polyketide synthase dehydratase / Zinc-binding dehydrogenase / : / : / Polyketide synthase dehydratase domain / : / Polyketide and metazoan fatty acid synthase dehydratase (PKS/mFAS DH) domain profile. / Polyketide synthase dehydratase N-terminal domain / PKS_DH / Polyketide synthase, dehydratase domain / Polyketide synthase, dehydratase domain superfamily / Polyketide synthase, ketoreductase domain / KR domain / Thiol Ester Dehydrase; Chain A / Malonyl-CoA ACP transacylase, ACP-binding / PKS_KR / Acyl transferase domain superfamily / Acyl transferase / Acyl transferase domain / Acyl transferase domain in polyketide synthase (PKS) enzymes. / Acyl transferase/acyl hydrolase/lysophospholipase / Alcohol dehydrogenase, N-terminal / Alcohol dehydrogenase GroES-like domain / Polyketide synthase, enoylreductase domain / Enoylreductase / Ketosynthase family 3 (KS3) domain profile. / Polyketide synthase, phosphopantetheine-binding domain / Phosphopantetheine attachment site / Beta-ketoacyl synthase / Beta-ketoacyl synthase, active site / Ketosynthase family 3 (KS3) active site signature. / Polyketide synthase, beta-ketoacyl synthase domain / Beta-ketoacyl synthase, N-terminal / Beta-ketoacyl synthase, C-terminal / Beta-ketoacyl synthase, N-terminal domain / Beta-ketoacyl synthase, C-terminal domain / GroES-like superfamily / Thiolase-like / Phosphopantetheine attachment site / Phosphopantetheine attachment site. / Phosphopantetheine attachment site / ACP-like superfamily / Carrier protein (CP) domain profile. / Phosphopantetheine binding ACP domain / NAD(P)-binding domain superfamily / Roll / Alpha Beta類似検索 - ドメイン・相同性 Phenolphthiocerol/phthiocerol polyketide synthase subunit C類似検索 - 構成要素 |
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生物種 | ![](img/tx_bacteria.gif) Mycobacterium tuberculosis (結核菌) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.9 Å |
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データ登録者 | Faille, A. / Gavalda, S. / Mourey, L. / Pedelacq, J.D. |
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資金援助 | フランス, 1件 組織 | 認可番号 | 国 |
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French National Research Agency | 09-BLAN-0298-01 | フランス |
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引用 | ジャーナル: J. Mol. Biol. / 年: 2017 タイトル: Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases. 著者: Faille, A. / Gavalda, S. / Slama, N. / Lherbet, C. / Maveyraud, L. / Guillet, V. / Laval, F. / Quemard, A. / Mourey, L. / Pedelacq, J.D. |
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履歴 | 登録 | 2016年6月7日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2017年8月30日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2019年10月16日 | Group: Data collection / カテゴリ: reflns_shell |
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改定 1.2 | 2024年1月10日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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