解像度: 1.66→25.952 Å / SU ML: 0.1 / 交差検証法: FREE R-VALUE / σ(F): 1.33 / 位相誤差: 12.65 詳細: THE AUTHORS STATE THAT ELECTRON DENSITY ANALYSIS REVEALED THAT THE MAIN CHAIN HAD A DOUBLE CONFORMATION ( FROM RESIDUE 211 TO 226), DUE TO ITS EXPECTED FLEXIBILITY (AS A CATALYTIC LOOP). ...詳細: THE AUTHORS STATE THAT ELECTRON DENSITY ANALYSIS REVEALED THAT THE MAIN CHAIN HAD A DOUBLE CONFORMATION ( FROM RESIDUE 211 TO 226), DUE TO ITS EXPECTED FLEXIBILITY (AS A CATALYTIC LOOP). VAL213 SHOWED A VERY CLEAR ELECTRON DENSITY IN CONFORMATION B, BUT IN CONTRAST, CONFORMATION A WAS DOMINANT FOR RESIDUES FROM 214 TO 218. THE VAL213 CONFORMER AND THE SER214 A CONFORMER WERE CONFLICTING AS A CONSEQUENCE OF THE DIFFERENT LOOP ARRANGEMENTS (OPEN AND CLOSED CONFORMATIONS). TAKING ALL THESE INTO ACCOUNT, THE AUTHORS STATE THAT THE VAL213 DOUBLE CONFORMATION IS THE SOLUTION THAT BETTER FITS THE DATASET AND THEREFORE, VAL213 (B CONFORMER) AND SER214 (A CONFORMER) ARE NOT LINKED.