SIGNALING PROTEIN / MULTIPLE SIGNALLING PATHWAYS / PHOSPHORYLATION / BINDING TO KINASE
Function / homology
Function and homology information
negative regulation of monoatomic ion transmembrane transport / small GTPase-mediated signal transduction / Regulation of localization of FOXO transcription factors / Activation of BAD and translocation to mitochondria / protein targeting / SARS-CoV-2 targets host intracellular signalling and regulatory pathways / Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex / SARS-CoV-1 targets host intracellular signalling and regulatory pathways / RHO GTPases activate PKNs / 14-3-3 protein binding ...negative regulation of monoatomic ion transmembrane transport / small GTPase-mediated signal transduction / Regulation of localization of FOXO transcription factors / Activation of BAD and translocation to mitochondria / protein targeting / SARS-CoV-2 targets host intracellular signalling and regulatory pathways / Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex / SARS-CoV-1 targets host intracellular signalling and regulatory pathways / RHO GTPases activate PKNs / 14-3-3 protein binding / substantia nigra development / Translocation of SLC2A4 (GLUT4) to the plasma membrane / TP53 Regulates Metabolic Genes / protein localization / transmembrane transporter binding / protein domain specific binding / focal adhesion / negative regulation of DNA-templated transcription / synapse / signal transduction / protein-containing complex / extracellular exosome / identical protein binding / membrane / cytosol / cytoplasm Similarity search - Function
Mass: 18.015 Da / Num. of mol.: 169 / Source method: isolated from a natural source / Formula: H2O
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Experimental details
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Experiment
Experiment
Method: X-RAY DIFFRACTION / Number of used crystals: 1
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Sample preparation
Crystal
Density Matthews: 2.3 Å3/Da / Density % sol: 46.9 % / Description: needle-like
Crystal grow
Temperature: 291 K / Method: vapor diffusion, hanging drop / pH: 6.4 Details: 24% PEG4K, 140 mM LI2SO4, 4 % of SATURATED NACL IN 80 mM MES AT pH 6.4; PROTEIN 7 mg/ml
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