Entry Database : PDB / ID : 5gnl Structure visualization Downloads & linksTitle Cytochrome P450 Vdh (CYP107BR1) F106V mutant ComponentsVitamin D(3) 25-hydroxylase Details Keywords OXIDOREDUCTASE / cytochrome P450Function / homology Function and homology informationFunction Domain/homology Component
cholestanetriol 26-monooxygenase / : / cholestanetetraol 26-dehydrogenase activity / : / cholest-4-en-3-one 26-monooxygenase activity / steroid hydroxylase activity / cholesterol catabolic process / iron ion binding / heme binding / cytoplasm Similarity search - Function Cytochrome P450, B-class / Cytochrome p450 / Cytochrome P450 / Cytochrome P450, conserved site / Cytochrome P450 cysteine heme-iron ligand signature. / Cytochrome P450 / Cytochrome P450 superfamily / Cytochrome P450 / Orthogonal Bundle / Mainly Alpha Similarity search - Domain/homologyBiological species Pseudonocardia autotrophica (bacteria)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 1.95 Å DetailsAuthors Yasutake, Y. / Tamura, T. Funding support Japan, 1items Details Hide detailsOrganization Grant number Country NEDO Japan
CitationJournal : Acta Crystallogr F Struct Biol Commun / Year : 2017Title : Structural insights into the mechanism of the drastic changes in enzymatic activity of the cytochrome P450 vitamin D3 hydroxylase (CYP107BR1) caused by a mutation distant from the active siteAuthors : Yasutake, Y. / Kameda, T. / Tamura, T. History Deposition Jul 22, 2016 Deposition site : PDBJ / Processing site : PDBJRevision 1.0 May 17, 2017 Provider : repository / Type : Initial releaseRevision 1.1 Nov 8, 2023 Group : Data collection / Database references / Refinement descriptionCategory : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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