登録情報 データベース : PDB / ID : 5fzt 構造の表示 ダウンロードとリンクタイトル The crystal structure of R7R8 in complex with a DLC1 fragment. 要素RHO GTPASE-ACTIVATING PROTEIN 7 TALIN-1 詳細キーワード STRUCTURAL PROTEIN / TALIN / DLC1 / FOCAL ADHESION機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
hindbrain morphogenesis / GRB2:SOS provides linkage to MAPK signaling for Integrins / Integrin signaling / Smooth Muscle Contraction / p130Cas linkage to MAPK signaling for integrins / SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion / MAP2K and MAPK activation / LIM domain binding / Platelet degranulation / negative regulation of focal adhesion assembly ... hindbrain morphogenesis / GRB2:SOS provides linkage to MAPK signaling for Integrins / Integrin signaling / Smooth Muscle Contraction / p130Cas linkage to MAPK signaling for integrins / SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion / MAP2K and MAPK activation / LIM domain binding / Platelet degranulation / negative regulation of focal adhesion assembly / vinculin binding / integrin activation / regulation of Rho protein signal transduction / cell-substrate junction assembly / focal adhesion assembly / regulation of small GTPase mediated signal transduction / negative regulation of stress fiber assembly / negative regulation of Rho protein signal transduction / cortical actin cytoskeleton organization / RHOB GTPase cycle / cortical actin cytoskeleton / RHOC GTPase cycle / phosphatidylserine binding / positive regulation of execution phase of apoptosis / RHOQ GTPase cycle / CDC42 GTPase cycle / RHOA GTPase cycle / heart morphogenesis / : / forebrain development / ruffle / RAC1 GTPase cycle / GTPase activator activity / SH2 domain binding / phosphatidylinositol binding / negative regulation of cell migration / caveola / neural tube closure / integrin-mediated signaling pathway / regulation of actin cytoskeleton organization / adherens junction / structural constituent of cytoskeleton / cell-cell adhesion / ruffle membrane / activation of cysteine-type endopeptidase activity involved in apoptotic process / actin filament binding / integrin binding / regulation of cell shape / actin cytoskeleton organization / cytoskeleton / membrane raft / negative regulation of cell population proliferation / intracellular membrane-bounded organelle / focal adhesion / lipid binding / apoptotic process / cell surface / signal transduction / endoplasmic reticulum / nucleus / plasma membrane / cytosol / cytoplasm 類似検索 - 分子機能 Talin, central domain / A middle domain of Talin 1 / : / Talin, R4 domain / in StAR and phosphatidylcholine transfer protein / Alpha-catenin/vinculin-like / Vinculin-binding site-containing domain / Talin, central / Talin, N-terminal F0 domain / Talin, central domain superfamily ... Talin, central domain / A middle domain of Talin 1 / : / Talin, R4 domain / in StAR and phosphatidylcholine transfer protein / Alpha-catenin/vinculin-like / Vinculin-binding site-containing domain / Talin, central / Talin, N-terminal F0 domain / Talin, central domain superfamily / Talin-1/2, rod-segment / Vinculin Binding Site / Talin, middle domain / N-terminal or F0 domain of Talin-head FERM / START domain / START domain / START domain profile. / I/LWEQ domain / I/LWEQ domain superfamily / I/LWEQ domain / I/LWEQ domain profile. / I/LWEQ domain / Phosphotyrosine-binding domain / Alpha-catenin/vinculin-like superfamily / FERM domain signature 1. / FERM conserved site / Rho GTPase-activating protein domain / RhoGAP domain / Rho GTPase-activating proteins domain profile. / GTPase-activator protein for Rho-like GTPases / FERM domain signature 2. / Rho GTPase activation protein / START-like domain superfamily / FERM central domain / FERM/acyl-CoA-binding protein superfamily / SAM domain (Sterile alpha motif) / FERM central domain / FERM superfamily, second domain / FERM domain / FERM domain profile. / Band 4.1 domain / Band 4.1 homologues / Sterile alpha motif domain / Sterile alpha motif/pointed domain superfamily / Four Helix Bundle (Hemerythrin (Met), subunit A) / PH-like domain superfamily / Ubiquitin-like domain superfamily / Up-down Bundle / Mainly Alpha 類似検索 - ドメイン・相同性 MALONATE ION / Talin-1 / Rho GTPase-activating protein 7 類似検索 - 構成要素生物種 MUS MUSCULUS (ハツカネズミ)HOMO SAPIENS (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.1 Å 詳細データ登録者 Zacharchenko, T. / Qian, X. / Goult, B.T. / Jethwa, D. / Almeida, T. / Ballestrem, C. / Critchley, D.R. / Lowy, D.R. / Barsukov, I.L. 引用ジャーナル : Structure / 年 : 2016タイトル : Ld Motif Recognition by Talin: Structure of the Talin-Dlc1 Complex.著者 : Zacharchenko, T. / Qian, X. / Goult, B.T. / Jethwa, D. / Almeida, T.B. / Ballestrem, C. / Critchley, D.R. / Lowy, D.R. / Barsukov, I.L. 履歴 登録 2016年3月15日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2016年4月27日 Provider : repository / タイプ : Initial release改定 1.1 2016年6月22日 Group : Database references改定 1.2 2016年6月29日 Group : Refinement description改定 1.3 2016年7月20日 Group : Database references改定 1.4 2024年1月10日 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other / Refinement description カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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