positive regulation of chromatin binding / histone H3K9me2/H3K9me3 demethylase activity / [histone H3]-trimethyl-L-lysine9 demethylase / positive regulation of double-strand break repair via nonhomologous end joining / histone H3K9 demethylase activity / histone demethylase activity / pericentric heterochromatin / cellular response to ionizing radiation / regulation of protein phosphorylation / double-strand break repair via homologous recombination ...positive regulation of chromatin binding / histone H3K9me2/H3K9me3 demethylase activity / [histone H3]-trimethyl-L-lysine9 demethylase / positive regulation of double-strand break repair via nonhomologous end joining / histone H3K9 demethylase activity / histone demethylase activity / pericentric heterochromatin / cellular response to ionizing radiation / regulation of protein phosphorylation / double-strand break repair via homologous recombination / HDMs demethylate histones / chromatin DNA binding / site of double-strand break / regulation of gene expression / damaged DNA binding / blood microparticle / chromatin remodeling / inflammatory response / chromatin / nucleoplasm / nucleus / metal ion binding 類似検索 - 分子機能
JmjN domain / jmjN domain / JmjN domain profile. / Small domain found in the jumonji family of transcription factors / Cupin / JmjC domain, hydroxylase / A domain family that is part of the cupin metalloenzyme superfamily. / JmjC domain / JmjC domain profile. / Jelly Rolls ...JmjN domain / jmjN domain / JmjN domain profile. / Small domain found in the jumonji family of transcription factors / Cupin / JmjC domain, hydroxylase / A domain family that is part of the cupin metalloenzyme superfamily. / JmjC domain / JmjC domain profile. / Jelly Rolls / Sandwich / Mainly Beta 類似検索 - ドメイン・相同性
プロトコル: SINGLE WAVELENGTH / 単色(M)・ラウエ(L): M / 散乱光タイプ: x-ray
放射波長
波長: 1.54178 Å / 相対比: 1
反射
解像度: 2.03→40 Å / Num. obs: 25162 / % possible obs: 92.5 % / Observed criterion σ(I): 2 / 冗長度: 6 % / Rmerge(I) obs: 0.43 / Net I/σ(I): 16.1
反射 シェル
解像度: 2→2.03 Å / 冗長度: 5.7 % / Rmerge(I) obs: 0.43 / Mean I/σ(I) obs: 4.4 / % possible all: 94
-
解析
ソフトウェア
名称
バージョン
分類
REFMAC
5.8.0073
精密化
DENZO
データ削減
SCALEPACK
データスケーリング
精密化
構造決定の手法: 分子置換 開始モデル: NONE 解像度: 2→64.5 Å / Cor.coef. Fo:Fc: 0.958 / Cor.coef. Fo:Fc free: 0.928 / SU B: 6.506 / SU ML: 0.097 / 交差検証法: THROUGHOUT / ESU R: 0.182 / ESU R Free: 0.164 / 立体化学のターゲット値: MAXIMUM LIKELIHOOD / 詳細: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS.
Rfactor
反射数
%反射
Selection details
Rfree
0.21141
1028
4.1 %
RANDOM
Rwork
0.15673
-
-
-
obs
0.15897
24068
92.45 %
-
溶媒の処理
イオンプローブ半径: 0.8 Å / 減衰半径: 0.8 Å / VDWプローブ半径: 1.2 Å / 溶媒モデル: BABINET MODEL WITH MASK