Entry | Database: PDB / ID: 5fii |
---|
Title | Structure of a human aspartate kinase, chorismate mutase and TyrA domain. |
---|
Components | PHENYLALANINE-4-HYDROXYLASE |
---|
Keywords | OXIDOREDUCTASE / TRANSFERASE |
---|
Function / homology | Function and homology information
Phenylketonuria / Phenylalanine metabolism / phenylalanine 4-monooxygenase / phenylalanine 4-monooxygenase activity / tyrosine biosynthetic process / catecholamine biosynthetic process / L-phenylalanine catabolic process / amino acid biosynthetic process / iron ion binding / cytosolSimilarity search - Function Phenylalanine-4-hydroxylase, tetrameric form / Eukaryotic phenylalanine-4-hydroxylase, catalytic domain / Tyrosine 3-monooxygenase-like / ACT domain / Aromatic amino acid hydroxylase, iron/copper binding site / Biopterin-dependent aromatic amino acid hydroxylases signature. / Aromatic amino acid hydroxylase / Aromatic amino acid hydroxylase, C-terminal / Aromatic amino acid monoxygenase, C-terminal domain superfamily / Aromatic amino acid hydroxylase superfamily ...Phenylalanine-4-hydroxylase, tetrameric form / Eukaryotic phenylalanine-4-hydroxylase, catalytic domain / Tyrosine 3-monooxygenase-like / ACT domain / Aromatic amino acid hydroxylase, iron/copper binding site / Biopterin-dependent aromatic amino acid hydroxylases signature. / Aromatic amino acid hydroxylase / Aromatic amino acid hydroxylase, C-terminal / Aromatic amino acid monoxygenase, C-terminal domain superfamily / Aromatic amino acid hydroxylase superfamily / Biopterin-dependent aromatic amino acid hydroxylase / Biopterin-dependent aromatic amino acid hydroxylase family profile. / ACT domain / ACT domain profile. / ACT domain / ACT-like domain / Alpha-Beta Plaits / 2-Layer Sandwich / Alpha BetaSimilarity search - Domain/homology |
---|
Biological species | HOMO SAPIENS (human) |
---|
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 1.8 Å |
---|
Authors | Patel, D. / Kopec, J. / Shrestha, L. / Fitzpatrick, F. / Pinkas, D. / Chaikuad, A. / Dixon-Clarke, S. / McCorvie, T.J. / Burgess-Brown, N. / von Delft, F. ...Patel, D. / Kopec, J. / Shrestha, L. / Fitzpatrick, F. / Pinkas, D. / Chaikuad, A. / Dixon-Clarke, S. / McCorvie, T.J. / Burgess-Brown, N. / von Delft, F. / Arrowsmith, C. / Edwards, A. / Bountra, C. / Yue, W.W. |
---|
Citation | Journal: Sci.Rep. / Year: 2016 Title: Structural Basis for Ligand-Dependent Dimerization of Phenylalanine Hydroxylase Regulatory Domain. Authors: Patel, D. / Kopec, J. / Fitzpatrick, F. / Mccorvie, T.J. / Yue, W.W. |
---|
History | Deposition | Sep 25, 2015 | Deposition site: PDBE / Processing site: PDBE |
---|
Revision 1.0 | Mar 30, 2016 | Provider: repository / Type: Initial release |
---|
Revision 1.1 | Oct 5, 2016 | Group: Database references |
---|
Revision 1.2 | May 8, 2024 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Other Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
---|
|
---|