Entry Database : PDB / ID : 5ff9 Structure visualization Downloads & linksTitle Noroxomaritidine/Norcraugsodine Reductase in Complex with NADP+ and tyramine ComponentsNoroxomaritidine/Norcraugsodine Reductase Details Keywords OXIDOREDUCTASE / short-chain dehydrogenase/reductase alkaloid biosynthesisFunction / homology Function and homology informationFunction Domain/homology Component
alkaloid metabolic process / Oxidoreductases; Acting on the CH-OH group of donors; With NAD+ or NADP+ as acceptor / oxidoreductase activity / nucleotide binding Similarity search - Function Tropinone reductase / Short-chain dehydrogenase/reductase, conserved site / Short-chain dehydrogenases/reductases family signature. / Enoyl-(Acyl carrier protein) reductase / Short-chain dehydrogenase/reductase SDR / NAD(P)-binding Rossmann-like Domain / NAD(P)-binding domain superfamily / Rossmann fold / 3-Layer(aba) Sandwich / Alpha Beta Similarity search - Domain/homology 4-(2-aminoethyl)phenol / NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE / Noroxomaritidine/norcraugsodine reductase Similarity search - ComponentBiological species Narcissus pseudonarcissus (daffodil)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution : 1.814 Å DetailsAuthors Jez, J.M. / Holland, C.K. Funding support United States, 1items Details Hide detailsOrganization Grant number Country National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) NIGMS-1RC2GM092561 United States
CitationJournal : J.Biol.Chem. / Year : 2016Title : Identification of a Noroxomaritidine Reductase with Amaryllidaceae Alkaloid Biosynthesis Related Activities.Authors : Kilgore, M.B. / Holland, C.K. / Jez, J.M. / Kutchan, T.M. History Deposition Dec 18, 2015 Deposition site : RCSB / Processing site : RCSBRevision 1.0 Jun 8, 2016 Provider : repository / Type : Initial releaseRevision 1.1 Jun 15, 2016 Group : Database referencesRevision 1.2 Aug 17, 2016 Group : Database referencesRevision 1.3 Sep 20, 2017 Group : Author supporting evidence / Database references / Derived calculationsCategory : citation / pdbx_audit_support / pdbx_struct_oper_listItem : _citation.journal_id_CSD / _pdbx_audit_support.funding_organization / _pdbx_struct_oper_list.symmetry_operationRevision 1.4 Dec 25, 2019 Group : Author supporting evidence / Category : pdbx_audit_support / Item : _pdbx_audit_support.funding_organizationRevision 1.5 Sep 27, 2023 Group : Data collection / Database references / Refinement descriptionCategory : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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