As (III) S-adenosylmethyltransferase cysteine mutant C72A bound Phenylarsine oxide (PhAs(III) in the arsenic binding site
Components
Arsenic methyltransferase
Keywords
TRANSFERASE / Arsenic Methyltransferase
Function / homology
Function and homology information
arsenite methyltransferase activity / arsonoacetate metabolic process / : / toxin metabolic process / methylation / metal ion binding / cytosol Similarity search - Function
Resolution: 1.97→27.31 Å / Cor.coef. Fo:Fc: 0.941 / Cor.coef. Fo:Fc free: 0.907 / SU B: 4.822 / SU ML: 0.134 / Cross valid method: THROUGHOUT / ESU R: 0.201 / ESU R Free: 0.183 / Stereochemistry target values: MAXIMUM LIKELIHOOD / Details: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
Rfactor
Num. reflection
% reflection
Selection details
Rfree
0.25016
1192
5.1 %
RANDOM
Rwork
0.19548
-
-
-
obs
0.19826
22159
89.48 %
-
Solvent computation
Ion probe radii: 0.8 Å / Shrinkage radii: 0.8 Å / VDW probe radii: 1.2 Å / Solvent model: MASK