Entry Database : PDB / ID : 50000000000000 Structure visualization Downloads & linksTitle Crystal structure of Eosinophil-derived neurotoxin in complex with the triazole double-headed ribonucleoside 11c ComponentsNon-secretory ribonuclease Details Keywords HYDROLASE / nucleaseFunction / homology Function and homology informationFunction Domain/homology Component
RNA catabolic process / pancreatic ribonuclease / ribonuclease A activity / RNA nuclease activity / innate immune response in mucosa / chemotaxis / azurophil granule lumen / defense response to virus / nucleic acid binding / lyase activity ... RNA catabolic process / pancreatic ribonuclease / ribonuclease A activity / RNA nuclease activity / innate immune response in mucosa / chemotaxis / azurophil granule lumen / defense response to virus / nucleic acid binding / lyase activity / Neutrophil degranulation / extracellular space / extracellular exosome / extracellular region Similarity search - Function P-30 Protein / Ribonuclease A-like domain / Pancreatic ribonuclease / Ribonuclease A, active site / Ribonuclease A-domain / Ribonuclease A-like domain superfamily / Pancreatic ribonuclease / Pancreatic ribonuclease family signature. / Pancreatic ribonuclease / Roll / Alpha Beta Similarity search - Domain/homologyBiological species Homo sapiens (human)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 1.34 Å DetailsAuthors Chatzileontiadou, D.S.M. / Stravodimos, G.A. / Kantsadi, A.L. / Leonidas, D.D. CitationJournal : Bioorg.Chem. / Year : 2015Title : Triazole double-headed ribonucleosides as inhibitors of eosinophil derived neurotoxin.Authors: Chatzileontiadou, D.S. / Parmenopoulou, V. / Manta, S. / Kantsadi, A.L. / Kylindri, P. / Griniezaki, M. / Kontopoulou, F. / Telopoulou, A. / Prokova, H. / Panagopoulos, D. / Boix, E. / ... Authors : Chatzileontiadou, D.S. / Parmenopoulou, V. / Manta, S. / Kantsadi, A.L. / Kylindri, P. / Griniezaki, M. / Kontopoulou, F. / Telopoulou, A. / Prokova, H. / Panagopoulos, D. / Boix, E. / Balatsos, N.A. / Komiotis, D. / Leonidas, D.D. History Deposition Sep 29, 2015 Deposition site : RCSB / Processing site : PDBERevision 1.0 Nov 18, 2015 Provider : repository / Type : Initial releaseRevision 1.1 Nov 25, 2015 Group : Experimental preparationRevision 1.2 Jan 17, 2018 Group : Data collection / Category : diffrn_source / Item : _diffrn_source.pdbx_synchrotron_siteRevision 1.3 Jan 10, 2024 Group : Data collection / Database references / Refinement descriptionCategory : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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