Entry Database : PDB / ID : 5daj Structure visualization Downloads & linksTitle Crystal structure of NalD, the secondary repressor of MexAB-OprM multidrug efflux pump in Pseudomonas aeruginosa ComponentsNalD Details Keywords TRANSCRIPTION REGULATOR / Repressor / Transcriptional regulator / TetR familyFunction / homology Function and homology informationFunction Domain/homology Component
negative regulation of transport / negative regulation of transmembrane transport / negative regulation of transporter activity / transcription cis-regulatory region binding / DNA-binding transcription factor activity / negative regulation of DNA-templated transcription / regulation of DNA-templated transcription / DNA binding Similarity search - Function Transcription regulator MAATS, C-terminal / MAATS-type transcriptional repressor, C-terminal region / DNA-binding HTH domain, TetR-type, conserved site / TetR-type HTH domain signature. / Tetracycline Repressor, domain 2 / Tetracyclin repressor-like, C-terminal domain superfamily / Tetracycline Repressor; domain 2 / Bacterial regulatory proteins, tetR family / DNA-binding HTH domain, TetR-type / TetR-type HTH domain profile. ... Transcription regulator MAATS, C-terminal / MAATS-type transcriptional repressor, C-terminal region / DNA-binding HTH domain, TetR-type, conserved site / TetR-type HTH domain signature. / Tetracycline Repressor, domain 2 / Tetracyclin repressor-like, C-terminal domain superfamily / Tetracycline Repressor; domain 2 / Bacterial regulatory proteins, tetR family / DNA-binding HTH domain, TetR-type / TetR-type HTH domain profile. / Homeobox-like domain superfamily / Orthogonal Bundle / Mainly Alpha Similarity search - Domain/homologyBiological species Pseudomonas aeruginosa PAO1 (bacteria)Method X-RAY DIFFRACTION / SYNCHROTRON / SAD / Resolution : 2.65 Å DetailsAuthors Chen, W.Z. / Wang, D. / Huang, S.Q. / Hu, Q.Y. / Liu, X.C. / Gan, J.H. / Chen, H. Funding support China, 1items Details Hide detailsOrganization Grant number Country National Science Foundation (NSF, China) China
CitationJournal : Mol.Microbiol. / Year : 2016Title : Novobiocin binding to NalD induces the expression of the MexAB-OprM pump in Pseudomonas aeruginosaAuthors : Chen, W.Z. / Wang, D. / Zhou, W. / Sang, H. / Liu, X.C. / Ge, Z. / Zhang, J. / Lan, L. / Yang, C.G. / Chen, H. History Deposition Aug 20, 2015 Deposition site : RCSB / Processing site : PDBJRevision 1.0 Apr 20, 2016 Provider : repository / Type : Initial releaseRevision 1.1 Jun 8, 2016 Group : Database referencesRevision 1.2 Apr 12, 2023 Group : Author supporting evidence / Database references ... Author supporting evidence / Database references / Derived calculations / Refinement description Category : citation / database_2 ... citation / database_2 / pdbx_audit_support / pdbx_struct_oper_list / struct_ncs_dom_lim Item : _citation.journal_id_CSD / _database_2.pdbx_DOI ... _citation.journal_id_CSD / _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_audit_support.funding_organization / _pdbx_struct_oper_list.symmetry_operation / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id
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