登録情報 | データベース: PDB / ID: 5cmn |
---|
タイトル | FLRT3 LRR domain in complex with LPHN3 Olfactomedin domain |
---|
要素 | - Latrophilin-3
- Leucine-rich repeat transmembrane protein FLRT3
|
---|
キーワード | Cell Adhesion/Carbohydrate Binding / LRR repeats / Cell Adhesion-Carbohydrate Binding complex / ADGRL3 |
---|
機能・相同性 | 機能・相同性情報
proepicardium cell migration involved in pericardium morphogenesis / head development / growth cone membrane / synaptic membrane adhesion / cell-cell adhesion via plasma-membrane adhesion molecules / embryonic morphogenesis / Signaling by ROBO receptors / fibroblast growth factor receptor binding / Downstream signaling of activated FGFR1 / chemorepellent activity ...proepicardium cell migration involved in pericardium morphogenesis / head development / growth cone membrane / synaptic membrane adhesion / cell-cell adhesion via plasma-membrane adhesion molecules / embryonic morphogenesis / Signaling by ROBO receptors / fibroblast growth factor receptor binding / Downstream signaling of activated FGFR1 / chemorepellent activity / positive regulation of synapse assembly / neuron projection extension / response to axon injury / fibroblast growth factor receptor signaling pathway / axonal growth cone / axon terminus / synapse assembly / extracellular matrix / synaptic membrane / axon guidance / G protein-coupled receptor activity / neuron migration / adenylate cyclase-activating G protein-coupled receptor signaling pathway / cell junction / neuron projection development / cell-cell junction / heart development / protein-macromolecule adaptor activity / carbohydrate binding / postsynaptic membrane / cell surface receptor signaling pathway / postsynaptic density / G protein-coupled receptor signaling pathway / axon / focal adhesion / glutamatergic synapse / calcium ion binding / endoplasmic reticulum membrane / protein homodimerization activity / extracellular space / membrane / plasma membrane / cytosol類似検索 - 分子機能 : / GPCR, family 2, latrophilin, C-terminal / GPCR, family 2, latrophilin / Latrophilin Cytoplasmic C-terminal region / D-galactoside/L-rhamnose binding SUEL lectin domain superfamily / GAIN domain, N-terminal / GPCR-Autoproteolysis INducing (GAIN) domain / D-galactoside/L-rhamnose binding SUEL lectin domain / Galactose binding lectin domain / SUEL-type lectin domain profile. ...: / GPCR, family 2, latrophilin, C-terminal / GPCR, family 2, latrophilin / Latrophilin Cytoplasmic C-terminal region / D-galactoside/L-rhamnose binding SUEL lectin domain superfamily / GAIN domain, N-terminal / GPCR-Autoproteolysis INducing (GAIN) domain / D-galactoside/L-rhamnose binding SUEL lectin domain / Galactose binding lectin domain / SUEL-type lectin domain profile. / Olfactomedin-like domain / Olfactomedin-like domain / Olfactomedin-like domain profile. / Olfactomedin-like domains / GAIN domain superfamily / GPCR proteolysis site, GPS, motif / GPS motif / GAIN-B domain profile. / G-protein-coupled receptor proteolytic site domain / Leucine-rich repeat N-terminal domain / Leucine rich repeat N-terminal domain / Cysteine-rich flanking region, C-terminal / Leucine rich repeat C-terminal domain / Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) / Ribonuclease Inhibitor / Hormone receptor domain / GPCR, family 2, extracellular hormone receptor domain / G-protein coupled receptors family 2 profile 1. / Domain present in hormone receptors / GPCR family 2, extracellular hormone receptor domain superfamily / G-protein coupled receptors family 2 signature 2. / GPCR, family 2, secretin-like, conserved site / Alpha-Beta Horseshoe / GPCR, family 2, secretin-like / 7 transmembrane receptor (Secretin family) / GPCR, family 2-like / G-protein coupled receptors family 2 profile 2. / Leucine rich repeat / Leucine-rich repeat, typical subtype / Leucine-rich repeats, typical (most populated) subfamily / Leucine-rich repeat profile. / Leucine-rich repeat / Fibronectin type-III domain profile. / Leucine-rich repeat domain superfamily / Fibronectin type III / Fibronectin type III superfamily / Immunoglobulin-like fold / Alpha Beta類似検索 - ドメイン・相同性 Adhesion G protein-coupled receptor L3 / Leucine-rich repeat transmembrane protein FLRT3類似検索 - 構成要素 |
---|
生物種 | Homo sapiens (ヒト) |
---|
手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 3.605 Å |
---|
データ登録者 | Lu, Y. / Salzman, G. / Arac, D. |
---|
引用 | ジャーナル: Structure / 年: 2015 タイトル: Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion. 著者: Lu, Y.C. / Nazarko, O.V. / Sando, R. / Salzman, G.S. / Sudhof, T.C. / Arac, D. |
---|
履歴 | 登録 | 2015年7月17日 | 登録サイト: RCSB / 処理サイト: RCSB |
---|
改定 1.0 | 2015年8月12日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2015年9月16日 | Group: Database references |
---|
改定 1.2 | 2020年7月29日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Structure summary カテゴリ: chem_comp / citation ...chem_comp / citation / entity / pdbx_chem_comp_identifier / pdbx_entity_nonpoly / pdbx_struct_oper_list / struct_conn / struct_site / struct_site_gen Item: _chem_comp.name / _chem_comp.type ..._chem_comp.name / _chem_comp.type / _citation.journal_id_CSD / _entity.pdbx_description / _pdbx_entity_nonpoly.name / _pdbx_struct_oper_list.symmetry_operation / _struct_conn.pdbx_role 解説: Carbohydrate remediation / Provider: repository / タイプ: Remediation |
---|
改定 1.3 | 2023年9月27日 | Group: Data collection / Database references ...Data collection / Database references / Refinement description / Structure summary カテゴリ: chem_comp / chem_comp_atom ...chem_comp / chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _chem_comp.pdbx_synonyms / _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
---|
|
---|