Entry Database : PDB / ID : 5br4 Structure visualization Downloads & linksTitle E. coli lactaldehyde reductase (FucO) M185C mutant ComponentsLactaldehyde reductase Details Keywords OXIDOREDUCTASE / NADH / FucO / MutantFunction / homology Function and homology informationFunction Domain/homology Component
lactaldehyde reductase activity / glycol catabolic process / propanediol metabolic process / lactaldehyde reductase / R-lactaldehyde reductase activity / S-lactaldehyde reductase activity / fucose catabolic process / L-fucose catabolic process / rhamnose catabolic process / alcohol dehydrogenase (NAD+) activity ... lactaldehyde reductase activity / glycol catabolic process / propanediol metabolic process / lactaldehyde reductase / R-lactaldehyde reductase activity / S-lactaldehyde reductase activity / fucose catabolic process / L-fucose catabolic process / rhamnose catabolic process / alcohol dehydrogenase (NAD+) activity / ferrous iron binding / nucleotide binding / protein homodimerization activity / metal ion binding / cytosol Similarity search - Function Lactaldehyde reductase / Iron-type alcohol dehydrogenase-like / Iron-containing alcohol dehydrogenases signature 2. / Iron-containing alcohol dehydrogenases signature 1. / Alcohol dehydrogenase, iron-type, conserved site / Dehydroquinate synthase-like, alpha domain / Dehydroquinate synthase-like - alpha domain / Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA / Iron-containing alcohol dehydrogenase / Rossmann fold - #1970 ... Lactaldehyde reductase / Iron-type alcohol dehydrogenase-like / Iron-containing alcohol dehydrogenases signature 2. / Iron-containing alcohol dehydrogenases signature 1. / Alcohol dehydrogenase, iron-type, conserved site / Dehydroquinate synthase-like, alpha domain / Dehydroquinate synthase-like - alpha domain / Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA / Iron-containing alcohol dehydrogenase / Rossmann fold - #1970 / Up-down Bundle / Rossmann fold / 3-Layer(aba) Sandwich / Mainly Alpha / Alpha Beta Similarity search - Domain/homologyBiological species Escherichia coli (E. coli)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution : 0.91 Å DetailsAuthors Cahn, J.K.B. / Brinkmann-Chen, S. / Arnold, F.H. CitationJournal : Protein Eng.Des.Sel. / Year : 2016Title : Mutations in adenine-binding pockets enhance catalytic properties of NAD(P)H-dependent enzymes.Authors : Cahn, J.K. / Baumschlager, A. / Brinkmann-Chen, S. / Arnold, F.H. History Deposition May 29, 2015 Deposition site : RCSB / Processing site : RCSBRevision 1.0 Dec 23, 2015 Provider : repository / Type : Initial releaseRevision 1.1 Sep 27, 2023 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_struct_oper_list Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_oper_list.symmetry_operation
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