Entry | Database: PDB / ID: 4wdc |
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Title | High-resolution crystal structure of water-soluble FraC (mutation F16P) |
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Components | Fragaceatoxin C |
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Keywords | TOXIN / Pore forming toxin / Protein-lipid interaction / actinoporin / lipid packing / cholesterol |
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Function / homology | Function and homology information
nematocyst / pore complex assembly / cytolysis in another organism / other organism cell membrane / channel activity / pore complex / monoatomic cation transport / toxin activity / lipid binding / extracellular region / identical protein bindingSimilarity search - Function Sea anemone actinoporin-like / Sea anemone cytotoxic protein / Cytolysin/lectin / Cytolysin/lectin / Mutm (Fpg) Protein; Chain: A, domain 2 / Sandwich / Mainly BetaSimilarity search - Domain/homology |
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Biological species | ![](img/tx_invertebrata.gif) Actinia fragacea (sea anemone) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 1.29 Å |
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Authors | Caaveiro, J.M.M. / Morante, K. / Tsumoto, K. |
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Citation | Journal: J.Biol.Chem. / Year: 2015 Title: A Pore-Forming Toxin Requires a Specific Residue for Its Activity in Membranes with Particular Physicochemical Properties Authors: Morante, K. / Caaveiro, J.M. / Tanaka, K. / Gonzalez-Manas, J.M. / Tsumoto, K. |
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History | Deposition | Sep 8, 2014 | Deposition site: RCSB / Processing site: PDBJ |
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Revision 1.0 | Mar 18, 2015 | Provider: repository / Type: Initial release |
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Revision 1.1 | Apr 8, 2015 | Group: Database references |
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Revision 1.2 | May 6, 2015 | Group: Database references |
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Revision 1.3 | Jan 29, 2020 | Group: Advisory / Data collection ...Advisory / Data collection / Database references / Derived calculations / Other / Source and taxonomy / Structure summary Category: citation / diffrn_source ...citation / diffrn_source / entity_src_gen / pdbx_database_status / pdbx_struct_oper_list / pdbx_validate_close_contact / pdbx_validate_symm_contact / struct_keywords Item: _citation.journal_id_CSD / _diffrn_source.pdbx_synchrotron_site ..._citation.journal_id_CSD / _diffrn_source.pdbx_synchrotron_site / _entity_src_gen.pdbx_alt_source_flag / _pdbx_database_status.pdb_format_compatible / _pdbx_struct_oper_list.symmetry_operation / _struct_keywords.text |
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Revision 1.4 | Mar 20, 2024 | Group: Data collection / Database references / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / refine_hist Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _refine_hist.number_atoms_solvent / _refine_hist.number_atoms_total / _refine_hist.pdbx_number_atoms_ligand / _refine_hist.pdbx_number_atoms_nucleic_acid / _refine_hist.pdbx_number_atoms_protein |
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