Entry | Database: PDB / ID: 4rcw |
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Title | Crystal structure of human Slitrk1 |
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Components | SLIT and NTRK-like protein 1 |
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Keywords | SIGNALING PROTEIN / Leucine rich-repeat / synaptic adhesion |
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Function / homology | Function and homology information
Receptor-type tyrosine-protein phosphatases / synaptic membrane adhesion / positive regulation of synapse assembly / adult behavior / positive regulation of axonogenesis / homeostatic process / regulation of presynapse assembly / GABA-ergic synapse / synapse assembly / axonogenesis ...Receptor-type tyrosine-protein phosphatases / synaptic membrane adhesion / positive regulation of synapse assembly / adult behavior / positive regulation of axonogenesis / homeostatic process / regulation of presynapse assembly / GABA-ergic synapse / synapse assembly / axonogenesis / postsynaptic density membrane / multicellular organism growth / glutamatergic synapse / synapse / extracellular region / plasma membraneSimilarity search - Function Slitrk family / Cysteine-rich flanking region, C-terminal / Leucine rich repeat C-terminal domain / Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) / Ribonuclease Inhibitor / Alpha-Beta Horseshoe / Leucine rich repeat / Leucine-rich repeat, typical subtype / Leucine-rich repeats, typical (most populated) subfamily / Leucine-rich repeat profile. ...Slitrk family / Cysteine-rich flanking region, C-terminal / Leucine rich repeat C-terminal domain / Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) / Ribonuclease Inhibitor / Alpha-Beta Horseshoe / Leucine rich repeat / Leucine-rich repeat, typical subtype / Leucine-rich repeats, typical (most populated) subfamily / Leucine-rich repeat profile. / Leucine-rich repeat / Leucine-rich repeat domain superfamily / Alpha BetaSimilarity search - Domain/homology |
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Biological species | Homo sapiens (human) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3.1925 Å |
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Authors | Kim, H.M. / Park, B.S. / Kim, D. / Lee, S.G. |
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Citation | Journal: Nat Commun / Year: 2014 Title: Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion. Authors: Um, J.W. / Kim, K.H. / Park, B.S. / Choi, Y. / Kim, D. / Kim, C.Y. / Kim, S.J. / Kim, M. / Ko, J.S. / Lee, S.G. / Choii, G. / Nam, J. / Heo, W.D. / Kim, E. / Lee, J.O. / Ko, J. / Kim, H.M. |
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History | Deposition | Sep 17, 2014 | Deposition site: RCSB / Processing site: RCSB |
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Revision 1.0 | Nov 19, 2014 | Provider: repository / Type: Initial release |
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Revision 1.1 | Nov 26, 2014 | Group: Database references |
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Revision 1.2 | Sep 20, 2023 | Group: Data collection / Database references / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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