- PDB-4mqv: Crystal complex of Rpa32c and Smarcal1 N-terminus -
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基本情報
登録情報
データベース: PDB / ID: 4mqv
タイトル
Crystal complex of Rpa32c and Smarcal1 N-terminus
要素
Replication protein A 32 kDa subunit
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1
キーワード
PROTEIN BINDING / Winged HTH Fold / Nucleus
機能・相同性
機能・相同性情報
protein localization to chromosome / DNA replication factor A complex / t-circle formation / regulation of DNA damage checkpoint / Removal of the Flap Intermediate / Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) / Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) / Removal of the Flap Intermediate from the C-strand / G-rich strand telomeric DNA binding / ATP-dependent DNA/DNA annealing activity ...protein localization to chromosome / DNA replication factor A complex / t-circle formation / regulation of DNA damage checkpoint / Removal of the Flap Intermediate / Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) / Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) / Removal of the Flap Intermediate from the C-strand / G-rich strand telomeric DNA binding / ATP-dependent DNA/DNA annealing activity / ATP-dependent chromatin remodeler activity / HDR through Single Strand Annealing (SSA) / Impaired BRCA2 binding to RAD51 / regulation of double-strand break repair via homologous recombination / telomeric DNA binding / replication fork processing / nuclear replication fork / Presynaptic phase of homologous DNA pairing and strand exchange / PCNA-Dependent Long Patch Base Excision Repair / HSF1 activation / Regulation of HSF1-mediated heat shock response / Activation of the pre-replicative complex / mismatch repair / Activation of ATR in response to replication stress / mitotic G1 DNA damage checkpoint signaling / telomere maintenance / Translesion synthesis by REV1 / Translesion synthesis by POLK / Translesion synthesis by POLI / Gap-filling DNA repair synthesis and ligation in GG-NER / helicase activity / nucleotide-excision repair / Fanconi Anemia Pathway / Recognition of DNA damage by PCNA-containing replication complex / Termination of translesion DNA synthesis / 加水分解酵素; 酸無水物に作用; 酸無水物に作用・細胞または細胞小器官の運動に関与 / double-strand break repair via homologous recombination / Translesion Synthesis by POLH / base-excision repair / G2/M DNA damage checkpoint / HDR through Homologous Recombination (HRR) / PML body / Dual Incision in GG-NER / Meiotic recombination / double-strand break repair via nonhomologous end joining / Formation of Incision Complex in GG-NER / Dual incision in TC-NER / Gap-filling DNA repair synthesis and ligation in TC-NER / single-stranded DNA binding / site of double-strand break / Processing of DNA double-strand break ends / protein phosphatase binding / Regulation of TP53 Activity through Phosphorylation / DNA replication / damaged DNA binding / chromosome, telomeric region / nuclear body / hydrolase activity / DNA repair / DNA damage response / ubiquitin protein ligase binding / chromatin / regulation of transcription by RNA polymerase II / enzyme binding / nucleoplasm / ATP binding / nucleus 類似検索 - 分子機能
HARP domain / HepA-related protein (HARP) / HARP domain profile. / Replication factor A protein 2 / Replication protein A, C-terminal / Replication protein A C terminal / Replication factor A protein-like / : / SNF2-like, N-terminal domain superfamily / SNF2, N-terminal ...HARP domain / HepA-related protein (HARP) / HARP domain profile. / Replication factor A protein 2 / Replication protein A, C-terminal / Replication protein A C terminal / Replication factor A protein-like / : / SNF2-like, N-terminal domain superfamily / SNF2, N-terminal / SNF2-related domain / Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain / Helicase conserved C-terminal domain / helicase superfamily c-terminal domain / Superfamilies 1 and 2 helicase C-terminal domain profile. / Superfamilies 1 and 2 helicase ATP-binding type-1 domain profile. / DEAD-like helicases superfamily / Helicase, C-terminal / Helicase superfamily 1/2, ATP-binding domain / Arc Repressor Mutant, subunit A / Winged helix DNA-binding domain superfamily / Winged helix-like DNA-binding domain superfamily / Nucleic acid-binding, OB-fold / P-loop containing nucleoside triphosphate hydrolase / Orthogonal Bundle / Mainly Alpha 類似検索 - ドメイン・相同性
Replication protein A 32 kDa subunit / SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 類似検索 - 構成要素
A: Replication protein A 32 kDa subunit B: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 C: Replication protein A 32 kDa subunit D: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1