登録情報 | データベース: PDB / ID: 4ihp |
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タイトル | Crystal structure of TgCDPK1 with inhibitor bound |
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要素 | Calmodulin-domain protein kinase 1 |
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キーワード | TRANSFERASE/TRANSFERASE INHIBITOR / Structural Genomics / Structural Genomics Consortium / SGC / Kinase / TRANSFERASE-TRANSFERASE INHIBITOR complex |
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機能・相同性 | 機能・相同性情報
calcium-dependent protein serine/threonine kinase activity / calcium/calmodulin-dependent protein kinase activity / calmodulin binding / intracellular signal transduction / calcium ion binding / ATP binding / membrane / nucleus / cytoplasm類似検索 - 分子機能 : / EF-hand domain pair / EF-hand, calcium binding motif / EF-Hand 1, calcium-binding site / EF-hand calcium-binding domain. / EF-hand calcium-binding domain profile. / EF-hand domain / EF-hand domain pair / Transferase(Phosphotransferase) domain 1 / Transferase(Phosphotransferase); domain 1 ...: / EF-hand domain pair / EF-hand, calcium binding motif / EF-Hand 1, calcium-binding site / EF-hand calcium-binding domain. / EF-hand calcium-binding domain profile. / EF-hand domain / EF-hand domain pair / Transferase(Phosphotransferase) domain 1 / Transferase(Phosphotransferase); domain 1 / Phosphorylase Kinase; domain 1 / Phosphorylase Kinase; domain 1 / Serine/threonine-protein kinase, active site / Serine/Threonine protein kinases active-site signature. / Protein kinase domain / Serine/Threonine protein kinases, catalytic domain / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily / 2-Layer Sandwich / Orthogonal Bundle / Mainly Alpha / Alpha Beta類似検索 - ドメイン・相同性 Chem-1FB / Calmodulin-domain protein kinase 1類似検索 - 構成要素 |
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生物種 | ![](img/tx_eukaryote.gif) Toxoplasma gondii (トキソプラズマ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.27 Å |
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データ登録者 | El Bakkouri, M. / Tempel, W. / Crandall, I.E. / Massad, T. / Loppnau, P. / Graslund, S. / Bountra, C. / Arrowsmith, C.H. / Edwards, A.M. / Kain, C.K. ...El Bakkouri, M. / Tempel, W. / Crandall, I.E. / Massad, T. / Loppnau, P. / Graslund, S. / Bountra, C. / Arrowsmith, C.H. / Edwards, A.M. / Kain, C.K. / Shokat, K.M. / Sibley, L.D. / Hui, R. / Structural Genomics Consortium (SGC) |
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引用 | ジャーナル: TO BE PUBLISHED タイトル: Crystal structure of TgCDPK1 with inhibitor bound 著者: El Bakkouri, M. / Tempel, W. / Crandall, I.E. / Massad, T. / Loppnau, P. / Graslund, S. / Bountra, C. / Arrowsmith, C.H. / Edwards, A.M. / Kain, C.K. / Shokat, K.M. / Sibley, L.D. / Hui, R. / ...著者: El Bakkouri, M. / Tempel, W. / Crandall, I.E. / Massad, T. / Loppnau, P. / Graslund, S. / Bountra, C. / Arrowsmith, C.H. / Edwards, A.M. / Kain, C.K. / Shokat, K.M. / Sibley, L.D. / Hui, R. / Structural Genomics Consortium (SGC) |
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履歴 | 登録 | 2012年12月19日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2014年1月15日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2017年11月15日 | Group: Refinement description / カテゴリ: software / Item: _software.name |
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改定 1.2 | 2024年2月28日 | Group: Data collection / Database references / Derived calculations カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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