登録情報 データベース : PDB / ID : 4h10 構造の表示 ダウンロードとリンクタイトル Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic Helix-Loop-Helix domains with E-box DNA 要素Aryl hydrocarbon receptor nuclear translocator-like protein 1 Circadian locomoter output cycles protein kaput E-box DNA antisense strand E-box DNA sense strand 詳細キーワード TRANSCRIPTION/DNA / bHLH / circadian transcription / TRANSCRIPTION-DNA complex機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
photoperiodism / CLOCK-BMAL transcription complex / positive regulation of skeletal muscle cell differentiation / regulation of hair cycle / positive regulation of protein acetylation / negative regulation of glucocorticoid receptor signaling pathway / maternal process involved in parturition / regulation of type B pancreatic cell development / bHLH transcription factor binding / regulation of cellular senescence ... photoperiodism / CLOCK-BMAL transcription complex / positive regulation of skeletal muscle cell differentiation / regulation of hair cycle / positive regulation of protein acetylation / negative regulation of glucocorticoid receptor signaling pathway / maternal process involved in parturition / regulation of type B pancreatic cell development / bHLH transcription factor binding / regulation of cellular senescence / chromatoid body / chromatin => GO:0000785 / positive regulation of circadian rhythm / negative regulation of TOR signaling / oxidative stress-induced premature senescence / negative regulation of cold-induced thermogenesis / response to redox state / protein acetylation / negative regulation of fat cell differentiation / regulation of protein catabolic process / E-box binding / regulation of insulin secretion / aryl hydrocarbon receptor binding / regulation of neurogenesis / histone acetyltransferase activity / histone acetyltransferase / BMAL1:CLOCK,NPAS2 activates circadian gene expression / DNA damage checkpoint signaling / cellular response to ionizing radiation / circadian regulation of gene expression / Heme signaling / Hsp90 protein binding / regulation of circadian rhythm / PPARA activates gene expression / PML body / chromatin DNA binding / positive regulation of inflammatory response / circadian rhythm / protein import into nucleus / sequence-specific double-stranded DNA binding / positive regulation of canonical Wnt signaling pathway / Circadian Clock / chromosome / positive regulation of NF-kappaB transcription factor activity / HATs acetylate histones / spermatogenesis / DNA-binding transcription activator activity, RNA polymerase II-specific / proteasome-mediated ubiquitin-dependent protein catabolic process / DNA-binding transcription factor binding / transcription regulator complex / sequence-specific DNA binding / protein dimerization activity / regulation of cell cycle / transcription cis-regulatory region binding / DNA-binding transcription factor activity, RNA polymerase II-specific / protein heterodimerization activity / RNA polymerase II cis-regulatory region sequence-specific DNA binding / DNA-binding transcription factor activity / intracellular membrane-bounded organelle / negative regulation of DNA-templated transcription / regulation of DNA-templated transcription / chromatin / regulation of transcription by RNA polymerase II / positive regulation of DNA-templated transcription / signal transduction / positive regulation of transcription by RNA polymerase II / DNA binding / nucleoplasm / nucleus / cytosol 類似検索 - 分子機能 : / Helix-loop-helix DNA-binding domain / MYOD Basic-Helix-Loop-Helix Domain, subunit B / Nuclear translocator / Helix-loop-helix DNA-binding domain / PAC motif / Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) / PAS domain / Helix-loop-helix DNA-binding domain superfamily / helix loop helix domain ... : / Helix-loop-helix DNA-binding domain / MYOD Basic-Helix-Loop-Helix Domain, subunit B / Nuclear translocator / Helix-loop-helix DNA-binding domain / PAC motif / Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) / PAS domain / Helix-loop-helix DNA-binding domain superfamily / helix loop helix domain / Myc-type, basic helix-loop-helix (bHLH) domain / Myc-type, basic helix-loop-helix (bHLH) domain profile. / PAS fold / PAS fold / PAS domain / PAS repeat profile. / PAS domain / PAS domain superfamily / Few Secondary Structures / Irregular 類似検索 - ドメイン・相同性 DNA / DNA (> 10) / Aryl hydrocarbon receptor nuclear translocator-like protein 1 / Circadian locomoter output cycles protein kaput 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.402 Å 詳細データ登録者 Wang, Z. / Su, X.-D. 引用ジャーナル : Cell Res. / 年 : 2013タイトル : Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic helix-loop-helix domains with E-box DNA.著者 : Wang, Z. / Wu, Y. / Li, L. / Su, X.D. 履歴 登録 2012年9月10日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2012年12月26日 Provider : repository / タイプ : Initial release改定 1.1 2013年2月20日 Group : Database references改定 1.2 2024年2月28日 Group : Data collection / Database referencesカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / struct_ref_seq_dif Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details
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