登録情報 データベース : PDB / ID : 3zfm 構造の表示 ダウンロードとリンクタイトル Crystal structure of EphB2 要素EPHRIN TYPE-B RECEPTOR 2 詳細 キーワード TRANSFERASE機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
regulation of T-helper 17 type immune response / hindbrain tangential cell migration / negative regulation of glutamate receptor signaling pathway / L1CAM interactions / vesicle-mediated intercellular transport / optic nerve morphogenesis / urogenital system development / postsynaptic membrane assembly / tight junction assembly / regulation of body fluid levels ... regulation of T-helper 17 type immune response / hindbrain tangential cell migration / negative regulation of glutamate receptor signaling pathway / L1CAM interactions / vesicle-mediated intercellular transport / optic nerve morphogenesis / urogenital system development / postsynaptic membrane assembly / tight junction assembly / regulation of body fluid levels / neuron projection retraction / axon guidance receptor activity / central nervous system projection neuron axonogenesis / negative regulation of axonogenesis / positive regulation of long-term neuronal synaptic plasticity / dendritic spine development / positive regulation of synaptic plasticity / camera-type eye morphogenesis / regulation of filopodium assembly / corpus callosum development / positive regulation of dendritic spine morphogenesis / regulation of behavioral fear response / positive regulation of glutamate receptor signaling pathway / regulation of autophagosome assembly / negative regulation of cell adhesion / commissural neuron axon guidance / dendritic spine morphogenesis / negative regulation of Ras protein signal transduction / positive regulation of protein localization to cell surface / axonal fasciculation / positive regulation of synapse assembly / regulation of receptor signaling pathway via JAK-STAT / EPH-Ephrin signaling / Ephrin signaling / inner ear morphogenesis / positive regulation of immunoglobulin production / retinal ganglion cell axon guidance / phosphorylation / regulation of blood coagulation / roof of mouth development / B cell activation / regulation of neuronal synaptic plasticity / EPH-ephrin mediated repulsion of cells / ephrin receptor signaling pathway / positive regulation of B cell proliferation / EPHB-mediated forward signaling / neuron projection maintenance / negative regulation of cytokine production involved in inflammatory response / axon guidance / hippocampal mossy fiber to CA3 synapse / learning / positive regulation of long-term synaptic potentiation / positive regulation of protein localization to plasma membrane / placental growth factor receptor activity / insulin receptor activity / vascular endothelial growth factor receptor activity / hepatocyte growth factor receptor activity / macrophage colony-stimulating factor receptor activity / platelet-derived growth factor alpha-receptor activity / platelet-derived growth factor beta-receptor activity / stem cell factor receptor activity / boss receptor activity / protein tyrosine kinase collagen receptor activity / brain-derived neurotrophic factor receptor activity / transmembrane-ephrin receptor activity / GPI-linked ephrin receptor activity / epidermal growth factor receptor activity / fibroblast growth factor receptor activity / insulin-like growth factor receptor activity / negative regulation of ERK1 and ERK2 cascade / receptor protein-tyrosine kinase / peptidyl-tyrosine phosphorylation / cellular response to amyloid-beta / positive regulation of tumor necrosis factor production / nervous system development / amyloid-beta binding / presynaptic membrane / cellular response to lipopolysaccharide / protein tyrosine kinase activity / angiogenesis / dendritic spine / postsynaptic membrane / learning or memory / postsynapse / positive regulation of cell migration / axon / signaling receptor binding / neuronal cell body / dendrite / positive regulation of gene expression / protein-containing complex binding / glutamatergic synapse / cell surface / extracellular region / nucleoplasm / ATP binding / identical protein binding / plasma membrane / cytosol 類似検索 - 分子機能 Ephrin type-B receptor 2, ligand binding domain / Tyrosine-protein kinase ephrin type A/B receptor-like / Tyrosine-protein kinase ephrin type A/B receptor-like / Ephrin receptor type-A /type-B / Ephrin receptor ligand binding domain / Tyrosine-protein kinase, receptor class V, conserved site / Ephrin receptor, transmembrane domain / : / Ephrin receptor ligand binding domain / Ephrin type-A receptor 2 transmembrane domain ... Ephrin type-B receptor 2, ligand binding domain / Tyrosine-protein kinase ephrin type A/B receptor-like / Tyrosine-protein kinase ephrin type A/B receptor-like / Ephrin receptor type-A /type-B / Ephrin receptor ligand binding domain / Tyrosine-protein kinase, receptor class V, conserved site / Ephrin receptor, transmembrane domain / : / Ephrin receptor ligand binding domain / Ephrin type-A receptor 2 transmembrane domain / Receptor tyrosine kinase class V signature 1. / Receptor tyrosine kinase class V signature 2. / Eph receptor ligand-binding domain profile. / Ephrin receptor ligand binding domain / Putative ephrin-receptor like / SAM domain (Sterile alpha motif) / SAM domain profile. / Sterile alpha motif. / Sterile alpha motif domain / Sterile alpha motif/pointed domain superfamily / Growth factor receptor cysteine-rich domain superfamily / Fibronectin type III domain / Fibronectin type 3 domain / Fibronectin type-III domain profile. / Galactose-binding-like domain superfamily / Fibronectin type III / Fibronectin type III superfamily / Tyrosine-protein kinase, catalytic domain / Tyrosine kinase, catalytic domain / Tyrosine protein kinases specific active-site signature. / Tyrosine-protein kinase, active site / Serine-threonine/tyrosine-protein kinase, catalytic domain / Protein tyrosine and serine/threonine kinase / Phosphorylase Kinase; domain 1 / Phosphorylase Kinase; domain 1 / Transferase(Phosphotransferase) domain 1 / Transferase(Phosphotransferase); domain 1 / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Immunoglobulin-like fold / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily / 2-Layer Sandwich / Orthogonal Bundle / Mainly Alpha / Alpha Beta 類似検索 - ドメイン・相同性生物種 HOMO SAPIENS (ヒト)手法 X線回折 / 分子置換 / 解像度 : 2.27 Å 詳細データ登録者 Debreczeni, J.E. / Overman, R. / Truman, C. / McAlister, M. / Attwood, T.K. 引用ジャーナル : Protein Sci. / 年 : 2014タイトル : Completing the Structural Family Portrait of the Human Ephb Tyrosine Kinase Domains著者 : Overman, R.C. / Debreczeni, J.E. / Truman, C.M. / Mcalister, M.S. / Attwood, T.K. 履歴 登録 2012年12月12日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2014年1月8日 Provider : repository / タイプ : Initial release改定 1.1 2014年3月5日 Group : Database references改定 1.2 2014年4月9日 Group : Database references改定 1.3 2014年5月7日 Group : Database references改定 1.4 2018年4月4日 Group : Data collection / カテゴリ : diffrn_source / Item : _diffrn_source.type改定 1.5 2024年5月8日 Group : Data collection / Database references / Otherカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf
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